Modulation of antigen-presenting cells by HDAC inhibitors: implications in autoimmunity and cancer

T-Bet Dependent Removal of Sin3A-Histone Deacetylase Complexes at the Ifng Locus Drives Th1 Differentiation

(2014) S. Chang et al.   JOURNAL OF IMMUNOLOGY

Histone Acetylation and Flagellin Are Essential for Legionella pneumophila-Induced Cytokine Expression

(2014) B. Schmeck et al.   JOURNAL OF IMMUNOLOGY

Signals and Combinatorial Functions of Histone Modifications

(2011) Tamaki Suganuma et al.   Annual Review of Biochemistry

HDAC11 plays an essential role in regulating OX40 ligand expression in Hodgkin lymphoma

(2011) D. Buglio et al.   BLOOD

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Variable HIV peptide stability in human cytosol is critical to epitope presentation and immune escape

(2011) Estibaliz Lazaro et al.   JOURNAL OF CLINICAL INVESTIGATION

Histone Deacetylase Inhibitor LAQ824 Augments Inflammatory Responses in Macrophages through Transcriptional Regulation of IL-10

(2011) Hongwei Wang et al.   JOURNAL OF IMMUNOLOGY

Cancer Immunoediting of the NK Group 2D Ligand H60a

(2011) T. O'Sullivan et al.   JOURNAL OF IMMUNOLOGY

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(2011) Silvia Consalvi et al.   MOLECULAR MEDICINE

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(2011) Christopher Reilly et al.   MOLECULAR MEDICINE

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(2011) Rainer Glauben et al.   MOLECULAR MEDICINE

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(2011) Jelena Vojinovic et al.   MOLECULAR MEDICINE

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(2011) Giuseppe Faraco et al.   MOLECULAR MEDICINE

Eradication of solid tumors using histone deacetylase inhibitors combined with immune-stimulating antibodies

(2011) A. J. Christiansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone deacetylases as regulators of inflammation and immunity

(2011) Melanie R. Shakespear et al.   TRENDS IN IMMUNOLOGY

Interferon-β exacerbates Th17-mediated inflammatory disease

(2011) Robert C. Axtell et al.   TRENDS IN IMMUNOLOGY

Exploration of the HDAC2 foot pocket: Synthesis and SAR of substituted N-(2-aminophenyl)benzamides

(2010) Jerome C. Bressi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Interferon   limits the effectiveness of melanoma peptide vaccines

(2010) H.-I. Cho et al.   BLOOD

Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection

(2010) T. Roger et al.   BLOOD

The novel inhibitor of histone deacetylase resminostat (RAS2410) inhibits proliferation and induces apoptosis in multiple myeloma (MM) cells

(2010) Sonja Mandl-Weber et al.   BRITISH JOURNAL OF HAEMATOLOGY

Defining and analyzing geoepidemiology and human autoimmunity

(2010) Yinon Shapira et al.   JOURNAL OF AUTOIMMUNITY

Mammalian target of rapamycin regulates miRNA-1 and follistatin in skeletal myogenesis

(2010) Yuting Sun et al.   JOURNAL OF CELL BIOLOGY

Histone Deacetylase Inhibitors Suppress Inflammatory Activation of Rheumatoid Arthritis Patient Synovial Macrophages and Tissue

(2010) Aleksander M. Grabiec et al.   JOURNAL OF IMMUNOLOGY

HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells

(2010) W Song et al.   LEUKEMIA

Histone deacetylases in RA: epigenetics and epiphenomena

(2010) Aleksander M Grabiec et al.   ARTHRITIS RESEARCH & THERAPY

Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritis

(2010) Tomoko Kawabata et al.   ARTHRITIS RESEARCH & THERAPY

A phase II multiple dose clinical trial of histone deacetylase inhibitor ITF2357 in patients with relapsed or progressive multiple myeloma

(2009) Monica Galli et al.   ANNALS OF HEMATOLOGY

HDAC3 influences phosphorylation of STAT3 at serine 727 by interacting with PP2A

(2009) Sumihito Togi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Enhanced Antitumor Activity Induced by Adoptive T-Cell Transfer and Adjunctive Use of the Histone Deacetylase Inhibitor LAQ824

(2009) D. D. Vo et al.   CANCER RESEARCH

Epigenetic Therapeutics in Autoimmune Disease

(2009) Moshe Szyf   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

A phosphorylation-acetylation switch regulates STAT1 signaling

(2009) O. H. Kramer et al.   GENES & DEVELOPMENT

Epigenetic control of skull morphogenesis by histone deacetylase 8

(2009) M. Haberland et al.   GENES & DEVELOPMENT

Recent insights into the genetic basis of systemic lupus erythematosus

(2009) K L Moser et al.   GENES AND IMMUNITY

The transcription repressor, ZEB1, cooperates with CtBP2 and HDAC1 to suppress IL-2 gene activation in T cells

(2009) J. Wang et al.   INTERNATIONAL IMMUNOLOGY

Phase II Multi-Institutional Trial of the Histone Deacetylase Inhibitor Romidepsin As Monotherapy for Patients With Cutaneous T-Cell Lymphoma

(2009) Richard L. Piekarz et al.   JOURNAL OF CLINICAL ONCOLOGY

Innate immunity, epigenetics and autoimmunity in rheumatoid arthritis

(2009) Hanna Maciejewska Rodrigues et al.   MOLECULAR IMMUNOLOGY

Introducing the acetylome

(2009) Karen T Smith et al.   NATURE BIOTECHNOLOGY

Histone deacetylases and the immunological network: implications in cancer and inflammation

(2009) A Villagra et al.   ONCOGENE

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

Decreased levels of autoantibody against histone deacetylase 3 in patients with systemic sclerosis

(2008) Yutaka Kuwatsuka et al.   AUTOIMMUNITY

Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells

(2008) H. J. P. M. Koenen et al.   BLOOD

Presentation of Telomerase Reverse Transcriptase, a Self-Tumor Antigen, is Down-regulated by Histone Deacetylase Inhibition

(2008) I. Pellicciotta et al.   CANCER RESEARCH

Epigenetic Enhancement of Antigen Processing and Presentation Promotes Immune Recognition of Tumors

(2008) A. F. Setiadi et al.   CANCER RESEARCH

Human HDAC7 Harbors a Class IIa Histone Deacetylase-specific Zinc Binding Motif and Cryptic Deacetylase Activity

(2008) Anja Schuetz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional Modulation Using HDACi Depsipeptide Promotes Immune Cell-Mediated Tumor Destruction of Murine B16 Melanoma

(2008) Takashi Murakami et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

HDAC2 deacetylates class II transactivator and suppresses its activity in macrophages and smooth muscle cells

(2008) Xiaocen Kong et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Predictors of the scleroderma phenotype in fibroblasts from systemic sclerosis patients

(2008) Q Qi et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Mice Lacking Histone Deacetylase 6 Have Hyperacetylated Tubulin but Are Viable and Develop Normally

(2008) Y. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Deletion of Histone Deacetylase 3 Reveals Critical Roles in S Phase Progression and DNA Damage Control

(2008) Srividya Bhaskara et al.   MOLECULAR CELL

The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance

(2008) Alejandro Villagra et al.   NATURE IMMUNOLOGY

Systemic Lupus Erythematosus

(2008) Anisur Rahman et al.   NEW ENGLAND JOURNAL OF MEDICINE