New paradigms in basophil development, regulation and function

Uncoupling of Induced Protein Processing from Maturation in Dendritic Cells Exposed to a Highly Antigenic Preparation from a Helminth Parasite

(2014) F. A. Marshall et al.   JOURNAL OF IMMUNOLOGY

IL-33, a Potent Inducer of Adaptive Immunity to Intestinal Nematodes

(2014) N. E. Humphreys et al.   JOURNAL OF IMMUNOLOGY

Approaching the Asymptote: 20 Years Later

(2009) Ruslan Medzhitov   IMMUNITY

Kallikrein 5 induces atopic dermatitis–like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome

(2009) Anaïs Briot et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1)

(2009) Svenja Steinfelder et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Basophils Can Directly Present or Cross-Present Antigen to CD8 Lymphocytes and Alter CD8 T Cell Differentiation into IL-10-Producing Phenotypes

(2009) S. Kim et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Limiting MHC Class II Expression to Dendritic Cells Alters the Ability to Develop Th2- Dependent Allergic Airway Inflammation

(2009) N. Niu et al.   JOURNAL OF IMMUNOLOGY

IL-3 Induces Basophil Expansion In Vivo by Directing Granulocyte-Monocyte Progenitors to Differentiate into Basophil Lineage-Restricted Progenitors in the Bone Marrow and by Increasing the Number of Basophil/Mast Cell Progenitors in the Spleen

(2009) K. Ohmori et al.   JOURNAL OF IMMUNOLOGY

Proteases Induce Production of Thymic Stromal Lymphopoietin by Airway Epithelial Cells through Protease-Activated Receptor-2

(2009) H. Kouzaki et al.   JOURNAL OF IMMUNOLOGY

IL-18 and IL-33 elicit Th2 cytokines from basophils via a MyD88- and p38α-dependent pathway

(2009) Kelly M. Kroeger et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Basophils trump dendritic cells as APCs for TH2 responses

(2009) Thomas A Wynn   NATURE IMMUNOLOGY

Basophils contribute to TH2-IgE responses in vivo via IL-4 production and presentation of peptide–MHC class II complexes to CD4+ T cells

(2009) Tomohiro Yoshimoto et al.   NATURE IMMUNOLOGY

MHC class II–dependent basophil–CD4+ T cell interactions promote TH2 cytokine–dependent immunity

(2009) Jacqueline G Perrigoue et al.   NATURE IMMUNOLOGY

Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell–stimulating programs in basophils

(2009) Kang Chen et al.   NATURE IMMUNOLOGY

Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response

(2009) Caroline L Sokol et al.   NATURE IMMUNOLOGY

Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell function

(2009) J. C. Massacand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human basophils activated by mast cell-derived IL-3 express retinaldehyde dehydrogenase-II and produce the immunoregulatory mediator retinoic acid

(2008) N. Spiegl et al.   BLOOD

Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33

(2008) T. Pecaric-Petkovic et al.   BLOOD

Basophil effector function and homeostasis during helminth infection

(2008) C. Ohnmacht et al.   BLOOD

Basophils Are Back!

(2008) Stephen J. Galli et al.   IMMUNITY

Basophils Play a Pivotal Role in Immunoglobulin-G-Mediated but Not Immunoglobulin-E-Mediated Systemic Anaphylaxis

(2008) Yusuke Tsujimura et al.   IMMUNITY

T cell-derived IL-3 plays key role in parasite infection-induced basophil production but is dispensable for in vivo basophil survival

(2008) T. Shen et al.   INTERNATIONAL IMMUNOLOGY

IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK Cells

(2008) M. D. Smithgall et al.   INTERNATIONAL IMMUNOLOGY

Alarming dendritic cells for Th2 induction

(2008) Andrew S. MacDonald et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Role of protease-activated receptors in inflammatory responses, innate and adaptive immunity

(2008) V. Shpacovitch et al.   JOURNAL OF LEUKOCYTE BIOLOGY

IL-3 is required for increases in blood basophils in nematode infection in mice and can enhance IgE-dependent IL-4 production by basophils in vitro

(2008) Chris S Lantz et al.   LABORATORY INVESTIGATION

CD103+ GALT DCs promote Foxp3+ regulatory T cells

(2008) K R R Siddiqui et al.   Mucosal Immunology

Basophils enhance immunological memory responses

(2008) Andrea Denzel et al.   NATURE IMMUNOLOGY