Decision by committee: new light on the CD4/CD8-lineage choice

The Zinc Finger Transcription Factor Zbtb7b Represses CD8-Lineage Gene Expression in Peripheral CD4+ T Cells

(2008) Lie Wang et al.   IMMUNITY

CD4-CD8 Lineage Commitment Is Regulated by a Silencer Element at the ThPOK Transcription-Factor Locus

(2008) Xi He et al.   IMMUNITY

Development of all CD4 T lineages requires nuclear factor TOX

(2008) Parinaz Aliahmad et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Putting ThPOK in place

(2008) J Jeremiah Bell et al.   NATURE IMMUNOLOGY

Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate

(2008) Sawako Muroi et al.   NATURE IMMUNOLOGY

ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage

(2008) Takeshi Egawa et al.   NATURE IMMUNOLOGY

Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4+ T cells

(2008) Lie Wang et al.   NATURE IMMUNOLOGY

Repression of the Transcription Factor Th-POK by Runx Complexes in Cytotoxic T Cell Development

(2008) R. Setoguchi et al.   SCIENCE