Journal
IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA
Volume 34, Issue 3, Pages 597-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.iac.2014.04.004
Keywords
Vaccine allergy; Vaccine components; Toxoids; Hypersensitivity; Egg; Gelatin; Children
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Overdiagnosis of vaccine allergy is considered a major public health problem. This article discusses the different types of allergic reactions after immunization based on the timing (immediate vs nonimmediate) and the extent of the reaction (local vs systemic). The vaccine components potentially responsible for an allergic reaction are discussed, as well as the management of patients with a history of reaction to a specific vaccine and those with a history of allergy to one of the vaccine components.
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