Journal
IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA
Volume 31, Issue 1, Pages 133-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.iac.2010.09.013
Keywords
Stress; Immunoregulation; Single nucleotide polymorphisms; Inflammation
Categories
Funding
- National Institutes of Health [1 CPI MP061018-02, 5 R21 AT002938-02, 1 R21 HL96086-01]
- Health Resources and Services Administration, Department of Health and Human Services
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Psychological stress has known effects on the immune system, including impacting effector and regulatory components. This can result in increased susceptibility to various infections, latent virus reactivation, and impact on immunoregulatory circuits. One of the great challenges in translational research is defining the risks associated with stress in specific patient populations and individuals. Future studies must include identification and validation of biomarkers that can categorize patient risk for adverse immune effects from various forms and degrees of psychological stress and how this impacts the course of their inflammatory disease.
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