Phosphorothioate-modified CpG oligodeoxynucleotides mimic autoantigens and reveal a potential role for Toll-like receptor 9 in receptor revision

TLR9-Activating DNA Up-Regulates ZAP70 via Sustained PKB Induction in IgM+ B Cells

(2014) I. Bekeredjian-Ding et al.   JOURNAL OF IMMUNOLOGY

CpG Drives Human Transitional B Cells to Terminal Differentiation and Production of Natural Antibodies

(2014) F. Capolunghi et al.   JOURNAL OF IMMUNOLOGY

Syk inhibition with fostamatinib leads to transitional B lymphocyte depletion

(2012) Paul M. Barr et al.   CLINICAL IMMUNOLOGY

A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemia

(2010) Prabodhika R. Mallikaratchy et al.   NUCLEIC ACIDS RESEARCH

Human Marginal Zone B Cells

(2009) Jean-Claude Weill et al.   Annual Review of Immunology

BCR-mediated uptake of antigen linked to TLR9 ligand stimulates B-cell proliferation and antigen-specific plasma cell formation

(2009) J. Eckl-Dorna et al.   BLOOD

NF-κB activity marks cells engaged in receptor editing

(2009) Emily J. Cadera et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Reduced c-myc Expression Levels Limit Follicular Mature B Cell Cycling in Response to TLR Signals

(2009) A. Meyer-Bahlburg et al.   JOURNAL OF IMMUNOLOGY

Altered B cell receptor signaling in human systemic lupus erythematosus

(2008) Scott A. Jenks et al.   AUTOIMMUNITY REVIEWS

The B Cell Receptor Governs the Subcellular Location of Toll-like Receptor 9 Leading to Hyperresponses to DNA-Containing Antigens

(2008) Akanksha Chaturvedi et al.   IMMUNITY

IRAK-4- and MyD88-Dependent Pathways Are Essential for the Removal of Developing Autoreactive B Cells in Humans

(2008) Isabelle Isnardi et al.   IMMUNITY

B cell receptor revision diminishes the autoreactive B cell response after antigen activation in mice

(2008) Ying-Hua Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Dynavax trial halted

(2008) Laura DeFrancesco   NATURE BIOTECHNOLOGY

SLP-65 regulates immunoglobulin light chain gene recombination through the PI(3)K-PKB-Foxo pathway

(2008) Sebastian Herzog et al.   NATURE IMMUNOLOGY