Epigenetic aspects of lymphocyte antigen receptor gene rearrangement or ‘when stochasticity completes randomness’

Genome Regulation by Long Noncoding RNAs

(2012) John L. Rinn et al.   Annual Review of Biochemistry

5-Methylcytosine DNA Demethylation: More Than Losing a Methyl Group

(2012) Don-Marc Franchini et al.   Annual Review of Genetics

DNA-binding factor CTCF and long-range gene interactions in V(D)J recombination and oncogene activation

(2012) C. Ribeiro de Almeida et al.   BLOOD

Chromosome organization in the nucleus – charting new territory across the Hi-Cs

(2012) Josée Dostie et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Higher-order chromatin structure: bridging physics and biology

(2012) Geoffrey Fudenberg et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The role of CTCF in regulating V(D)J recombination

(2012) Julie Chaumeil et al.   CURRENT OPINION IN IMMUNOLOGY

Highly diverse TCRα chain repertoire of pre-immune CD8+T cells reveals new insights in gene recombination

(2012) Raphael Genolet et al.   EMBO JOURNAL

V(D)J Recombinase-Mediated TCR   Locus Gene Usage and Coding Joint Processing in Peripheral T Cells during Perinatal and Pediatric Development

(2012) J. M. Murray et al.   JOURNAL OF IMMUNOLOGY

Clonal allelic predetermination of immunoglobulin-κ rearrangement

(2012) Marganit Farago et al.   NATURE

Localized epigenetic changes induced by DH recombination restricts recombinase to DJH junctions

(2012) Ramesh Subrahmanyam et al.   NATURE IMMUNOLOGY

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

Functional characterization of an active Rag-like transposase

(2012) Cary G Hencken et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Real-time monitoring of RAG-catalyzed DNA cleavage unveils dynamic changes in coding end association with the coding end complex

(2012) Guannan Wang et al.   NUCLEIC ACIDS RESEARCH

Chromatin conformation governs T-cell receptor J  gene segment usage

(2012) W. Ndifon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tcra gene recombination is supported by a Tcra enhancer- and CTCF-dependent chromatin hub

(2012) H.-Y. Shih et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Statistical inference of the generation probability of T-cell receptors from sequence repertoires

(2012) A. Murugan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRIM28 mediates chromatin modifications at the TCR  enhancer and regulates the development of T and natural killer T cells

(2012) X.-F. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Noncoding transcription within the Igh distal VH region at PAIR elements affects the 3D structure of the Igh locus in pro-B cells

(2012) J. Verma-Gaur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The adjustable nucleosome: an epigenetic signaling module

(2012) Bryan M. Turner   TRENDS IN GENETICS

Cohesin, CTCF and lymphocyte antigen receptor locus rearrangement

(2012) Vlad C. Seitan et al.   TRENDS IN IMMUNOLOGY

V(D)J Recombination: Mechanisms of Initiation

(2011) David G. Schatz et al.   Annual Review of Genetics

Cellular Decision Making and Biological Noise: From Microbes to Mammals

(2011) Gábor Balázsi et al.   CELL

No-Nonsense Functions for Long Noncoding RNAs

(2011) Takashi Nagano et al.   CELL

The DNA-Binding Protein CTCF Limits Proximal Vκ Recombination and Restricts κ Enhancer Interactions to the Immunoglobulin κ Light Chain Locus

(2011) Claudia Ribeiro de Almeida et al.   IMMUNITY

The Distal VH Gene Cluster of the Igh Locus Contains Distinct Regulatory Elements with Pax5 Transcription Factor-Dependent Activity in Pro-B Cells

(2011) Anja Ebert et al.   IMMUNITY

CTCF-binding elements mediate control of V(D)J recombination

(2011) Chunguang Guo et al.   NATURE

The RAG2 C terminus suppresses genomic instability and lymphomagenesis

(2011) Ludovic Deriano et al.   NATURE

A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation

(2011) Vlad C. Seitan et al.   NATURE

CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells

(2011) S. C. Degner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pro-B cells sense productive immunoglobulin heavy chain rearrangement irrespective of polypeptide production

(2011) J. Lutz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

The In Vivo Pattern of Binding of RAG1 and RAG2 to Antigen Receptor Loci

(2010) Yanhong Ji et al.   CELL

Transcription and recombination factories: common features?

(2010) Joseph S Lucas et al.   CURRENT OPINION IN CELL BIOLOGY

Distinct contracted conformations of theTcra/Tcrdlocus duringTcraandTcrdrecombination

(2010) Han-Yu Shih et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination

(2010) Yanhong Ji et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TCR  Allelic Exclusion in Dynamical Models of V(D)J Recombination Based on Allele Independence

(2010) E. Farcot et al.   JOURNAL OF IMMUNOLOGY

Antigen Receptor Allelic Exclusion: An Update and Reappraisal

(2010) B. L. Brady et al.   JOURNAL OF IMMUNOLOGY

Functional roles for noise in genetic circuits

(2010) Avigdor Eldar et al.   NATURE

An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells

(2010) Louise M D'Cruz et al.   NATURE IMMUNOLOGY

Chromatin structure and the inheritance of epigenetic information

(2010) Raphaël Margueron et al.   NATURE REVIEWS GENETICS

Autoinhibition of DNA cleavage mediated by RAG1 and RAG2 is overcome by an epigenetic signal in V(D)J recombination

(2010) G. J. Grundy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Numerical Modelling Of The V-J Combinations Of The T Cell Receptor TRA/TRD Locus

(2010) Florence Thuderoz et al.   PLoS Computational Biology

Chromatin Architecture and the Generation of Antigen Receptor Diversity

(2009) Suchit Jhunjhunwala et al.   CELL

A 220-nucleotide deletion of the intronic enhancer reveals an epigenetic hierarchy in immunoglobulin heavy chain locus activation

(2009) Tirtha Chakraborty et al.   JOURNAL OF EXPERIMENTAL MEDICINE

H3K4me3 Stimulates the V(D)J RAG Complex for Both Nicking and Hairpinning in trans in Addition to Tethering in cis: Implications for Translocations

(2009) Noriko Shimazaki et al.   MOLECULAR CELL

RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

(2009) Susannah L Hewitt et al.   NATURE IMMUNOLOGY

The origins of the Rag genes—From transposition to V(D)J recombination

(2009) Sebastian D. Fugmann   SEMINARS IN IMMUNOLOGY

Genetics and epigenetics: stability and plasticity during cellular differentiation

(2009) Fabio Mohn et al.   TRENDS IN GENETICS

The 3D Structure of the Immunoglobulin Heavy-Chain Locus: Implications for Long-Range Genomic Interactions

(2008) Suchit Jhunjhunwala et al.   CELL

Choreography of Ig allelic exclusion

(2008) Howard Cedar et al.   CURRENT OPINION IN IMMUNOLOGY

Regulation of Immunoglobulin Light-Chain Recombination by the Transcription Factor IRF-4 and the Attenuation of Interleukin-7 Signaling

(2008) Kristen Johnson et al.   IMMUNITY

Initiation of allelic exclusion by stochastic interaction of Tcrb alleles with repressive nuclear compartments

(2008) Ryan J Schlimgen et al.   NATURE IMMUNOLOGY

Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros

(2008) Damien Reynaud et al.   NATURE IMMUNOLOGY