The DC-HIL ligand syndecan-4 is a negative regulator of T-cell allo-reactivity responsible for graft-versus-host disease

Inhibition of T-cell activation by syndecan-4 is mediated by CD148 through protein tyrosine phosphatase activity

(2011) Jin-Sung Chung et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Depleting Syndecan-4+ T Lymphocytes Using Toxin-Bearing Dendritic Cell-Associated Heparan Sulfate Proteoglycan-Dependent Integrin Ligand: A New Opportunity for Treating Activated T Cell-Driven Disease

(2010) H. Akiyoshi et al.   JOURNAL OF IMMUNOLOGY

The DC-HIL/syndecan-4 pathway inhibits human allogeneic T-cell responses

(2009) Jin-Sung Chung et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

(2009) Loise M. Francisco et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Binding of DC-HIL to Dermatophytic Fungi Induces Tyrosine Phosphorylation and Potentiates Antigen Presenting Cell Function

(2009) J.-S. Chung et al.   JOURNAL OF IMMUNOLOGY

Graft-versus-host disease

(2009) James LM Ferrara et al.   LANCET

Adoptive transfer of allogeneic tumor-specific T cells mediates effective regression of large tumors across major histocompatibility barriers

(2008) A. Boni et al.   BLOOD