Differential requirements of CD4+T-cell signals for effector cytotoxic T-lymphocyte (CTL) priming and functional memory CTL development at higher CD8+T-cell precursor frequency

CD8+ T Cells Targeting a Single Immunodominant Epitope are Sufficient for Elimination of Established SV40 T Antigen-Induced Brain Tumors

(2014) A. M. Tatum et al.   JOURNAL OF IMMUNOLOGY

CD4+ Th-APC with Acquired Peptide/MHC Class I and II Complexes Stimulate Type 1 Helper CD4+ and Central Memory CD8+ T Cell Responses

(2014) C. S. Umeshappa et al.   JOURNAL OF IMMUNOLOGY

CD4 Help Regulates Expression of Crucial Genes Involved in CD8 T Cell Memory and Sensitivity to Regulatory Elements

(2014) L. Rapetti et al.   JOURNAL OF IMMUNOLOGY

A Critical Precursor Frequency of Donor-Reactive CD4+ T Cell Help Is Required for CD8+ T Cell-Mediated CD28/CD154-Independent Rejection

(2014) M. L. Ford et al.   JOURNAL OF IMMUNOLOGY

CD40 on APCs Is Needed for Optimal Programming, Maintenance, and Recall of CD8+ T Cell Memory Even in the Absence of CD4+ T Cell Help

(2014) M. G. H. Hernandez et al.   JOURNAL OF IMMUNOLOGY

Naive Precursor Frequencies and MHC Binding Rather Than the Degree of Epitope Diversity Shape CD8+ T Cell Immunodominance

(2014) M. F. Kotturi et al.   JOURNAL OF IMMUNOLOGY

Regulators of T-cell memory generation: TCR signals versus CD4+ help?

(2011) Channakeshava Sokke Umeshappa et al.   IMMUNOLOGY AND CELL BIOLOGY

Intrinsic IL-21 Signaling Is Critical for CD8 T Cell Survival and Memory Formation in Response to Vaccinia Viral Infection

(2011) P. Novy et al.   JOURNAL OF IMMUNOLOGY

Immunodominance of HLA-A2-Restricted Hepatitis C Virus-Specific CD8+ T Cell Responses Is Linked to Naive-Precursor Frequency

(2011) J. Schmidt et al.   JOURNAL OF VIROLOGY

Adoptive immunotherapy of cancer using ex vivo expanded human γδ T cells: A new approach

(2010) Pouneh Dokouhaki et al.   CANCER LETTERS

Tumor-derived HLA-G1 acquisition by monocytes through trogocytosis: possible functional consequences

(2010) Channakeshava Sokke Umeshappa et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Dendritic Cell-Based Immunotherapy for Prostate Cancer

(2010) Hanka Jähnisch et al.   Clinical & Developmental Immunology

Therapeutic cancer vaccines: are we there yet?

(2010) Christopher A. Klebanoff et al.   IMMUNOLOGICAL REVIEWS

Naturally occurring tumor-specific CD8+ T-cell precursors in individuals with and without cancer

(2010) Vaios Karanikas et al.   IMMUNOLOGY AND CELL BIOLOGY

Synergistic Antitumor Effects of Regulatory T Cell Blockade Combined with Pemetrexed in Murine Malignant Mesothelioma

(2010) M. Anraku et al.   JOURNAL OF IMMUNOLOGY

Th Cells Act Via Two Synergistic Pathways To Promote Antiviral CD8+ T Cell Responses

(2010) M. Wiesel et al.   JOURNAL OF IMMUNOLOGY

High-Frequency Alloreactive T Cells Augment Effector Function of Low-Frequency CD8+ T-Cell Responses Under CD28/CD154 Blockade

(2010) Tamara L. Floyd et al.   TRANSPLANTATION

Imprinted DC mediate the immune-educating effect of early-life microbial exposure

(2009) Lei Jiao et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Selected Toll-like Receptor Ligands and Viruses Promote Helper-Independent Cytotoxic T Cell Priming by Upregulating CD40L on Dendritic Cells

(2009) Susan Johnson et al.   IMMUNITY

Different mechanisms regulate CD4+ T cell independent induction of oral and nasal tolerance of CD8+ T cells

(2009) Hendrik van den Berg et al.   IMMUNOBIOLOGY

Self-antigen–specific CD8+T cell precursor frequency determines the quality of the antitumor immune response

(2009) Gabrielle A. Rizzuto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T cell precursor frequency differentially affects CTL responses under different immune conditions

(2008) Zhenmin Ye et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endogenous Naive CD8+ T Cell Precursor Frequency Regulates Primary and Memory Responses to Infection

(2008) Joshua J. Obar et al.   IMMUNITY

Treatment of Metastatic Melanoma with Autologous CD4+ T Cells against NY-ESO-1

(2008) Naomi N. Hunder et al.   NEW ENGLAND JOURNAL OF MEDICINE

Advances in Specific Immunotherapy for Prostate Cancer

(2007) Andrea Kiessling et al.   EUROPEAN UROLOGY