Regulation of B-cell responses by Toll-like receptors

CpG Drives Human Transitional B Cells to Terminal Differentiation and Production of Natural Antibodies

(2014) F. Capolunghi et al.   JOURNAL OF IMMUNOLOGY

Viral Double-Stranded RNA Triggers Ig Class Switching by Activating Upper Respiratory Mucosa B Cells through an Innate TLR3 Pathway Involving BAFF

(2014) W. Xu et al.   JOURNAL OF IMMUNOLOGY

TLR-Activated B Cells Suppress T Cell-Mediated Autoimmunity

(2014) V. Lampropoulou et al.   JOURNAL OF IMMUNOLOGY

Antiviral memory CD8 T-cell differentiation, maintenance, and secondary expansion occur independently of MyD88

(2011) A. H. Rahman et al.   BLOOD

Systematic Discovery of TLR Signaling Components Delineates Viral-Sensing Circuits

(2011) Nicolas Chevrier et al.   CELL

Differential impact of Toll-like receptor signaling on distinct B cell subpopulations

(2011) Almut Meyer-Bahlburg   Frontiers in Bioscience-Landmark

Innate Immune Sensing of Retroviral Infection via Toll-like Receptor 7 Occurs upon Viral Entry

(2011) Melissa Kane et al.   IMMUNITY

Unc93B1 Restricts Systemic Lethal Inflammation by Orchestrating Toll-like Receptor 7 and 9 Trafficking

(2011) Ryutaro Fukui et al.   IMMUNITY

Selective Utilization of Toll-like Receptor and MyD88 Signaling in B Cells for Enhancement of the Antiviral Germinal Center Response

(2011) Baidong Hou et al.   IMMUNITY

Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity

(2011) Yiqi Guo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MyD88 Plays an Essential Role in Inducing B Cells Capable of Differentiating into Antibody-Secreting Cells after Vaccination

(2011) S.-M. Kang et al.   JOURNAL OF VIROLOGY

Programming the magnitude and persistence of antibody responses with innate immunity

(2011) Sudhir Pai Kasturi et al.   NATURE

Broad neutralization coverage of HIV by multiple highly potent antibodies

(2011) Laura M. Walker et al.   NATURE

CD40 Signaling Synergizes with TLR-2 in the BCR Independent Activation of Resting B Cells

(2011) Shweta Jain et al.   PLoS One

Decreased Dengue Replication and an Increased Anti-viral Humoral Response with the use of Combined Toll-Like Receptor 3 and 7/8 Agonists in Macaques

(2011) Carlos A. Sariol et al.   PLoS One

Toll-Like Receptor Agonists Synergize with CD40L to Induce Either Proliferation or Plasma Cell Differentiation of Mouse B Cells

(2011) Emmanuelle Boeglin et al.   PLoS One

Successful Transmission of a Retrovirus Depends on the Commensal Microbiota

(2011) M. Kane et al.   SCIENCE

Toll-like receptor driven B cell activation in the induction of systemic autoimmunity

(2011) Nathaniel M. Green et al.   SEMINARS IN IMMUNOLOGY

Toll-like Receptor 7 Controls the Anti-Retroviral Germinal Center Response

(2011) Edward P. Browne   PLoS Pathogens

Toll-like Receptor 4 Signaling by Follicular Dendritic Cells Is Pivotal for Germinal Center Onset and Affinity Maturation

(2010) Alexandre Garin et al.   IMMUNITY

The germinal center reaction

(2010) Dominique Gatto et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

TLR1/2, TLR7, and TLR9 Signals Directly Activate Human Peripheral Blood Naive and Memory B Cell Subsets to Produce Cytokines, Chemokines, and Hematopoietic Growth Factors

(2010) Sudhanshu Agrawal et al.   JOURNAL OF CLINICAL IMMUNOLOGY

TLR Ligation Triggers Somatic Hypermutation in Transitional B Cells Inducing the Generation of IgM Memory B Cells

(2010) A. Aranburu et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: IL-21 and TLR Signaling Regulate Germinal Center Responses in a B Cell-Intrinsic Manner

(2010) J. Bessa et al.   JOURNAL OF IMMUNOLOGY

MyD88 Signaling Is Indispensable for Primary Influenza A Virus Infection but Dispensable for Secondary Infection

(2010) S.-U. Seo et al.   JOURNAL OF VIROLOGY

The Innate Immune Adaptor Molecule MyD88 Restricts West Nile Virus Replication and Spread in Neurons of the Central Nervous System

(2010) K. J. Szretter et al.   JOURNAL OF VIROLOGY

Interleukin-10 Mediated Autoregulation of Murine B-1 B-Cells and Its Role in Borrelia hermsii Infection

(2010) Vishal Sindhava et al.   PLoS One

Regulation of Adaptive Immunity by the Innate Immune System

(2010) A. Iwasaki et al.   SCIENCE

HIV vaccines: lessons learned and the way forward

(2010) Jerome H Kim et al.   Current Opinion in HIV and AIDS

Plasma cell toll-like receptor (TLR) expression differs from that of B cells, and plasma cell TLR triggering enhances immunoglobulin production

(2009) Marcus Dorner et al.   IMMUNOLOGY

Toll-like receptor 7-induced immune response to cutaneous West Nile virus infection

(2009) T. Welte et al.   JOURNAL OF GENERAL VIROLOGY

Reduced c-myc Expression Levels Limit Follicular Mature B Cell Cycling in Response to TLR Signals

(2009) A. Meyer-Bahlburg et al.   JOURNAL OF IMMUNOLOGY

Murine B Cell Response to TLR7 Ligands Depends on an IFN-  Feedback Loop

(2009) N. M. Green et al.   JOURNAL OF IMMUNOLOGY

Superantigen- and TLR-Dependent Activation of Tonsillar B Cells after Receptor-Mediated Endocytosis

(2009) J. Jendholm et al.   JOURNAL OF IMMUNOLOGY

TLR Cross-Talk Specifically Regulates Cytokine Production by B Cells from Chronic Inflammatory Disease Patients

(2009) M. Jagannathan et al.   JOURNAL OF IMMUNOLOGY

Vesicular Stomatitis Virus M Protein Mutant Stimulates Maturation of Toll-Like Receptor 7 (TLR7)-Positive Dendritic Cells through TLR-Dependent and -Independent Mechanisms

(2009) M. Ahmed et al.   JOURNAL OF VIROLOGY

Unbiased Reconstruction of a Mammalian Transcriptional Network Mediating Pathogen Responses

(2009) I. Amit et al.   SCIENCE

Myd88 Is Required for an Antibody Response to Retroviral Infection

(2009) Edward P. Browne et al.   PLoS Pathogens

Mechanism and Regulation of Class Switch Recombination

(2008) Janet Stavnezer et al.   Annual Review of Immunology

B cell autonomous TLR signaling and autoimmunity

(2008) Almut Meyer-Bahlburg et al.   AUTOIMMUNITY REVIEWS

Comparison of human B cell activation by TLR7 and TLR9 agonists

(2008) John A Hanten et al.   BMC IMMUNOLOGY

Viruses induce high expression of BAFF by salivary gland epithelial cells through TLR- and type-I IFN-dependent and -independent pathways

(2008) Marc Ittah et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IRAK-4- and MyD88-Dependent Pathways Are Essential for the Removal of Developing Autoreactive B Cells in Humans

(2008) Isabelle Isnardi et al.   IMMUNITY

Toll-like Receptors Activate Innate and Adaptive Immunity by using Dendritic Cell-Intrinsic and -Extrinsic Mechanisms

(2008) Baidong Hou et al.   IMMUNITY

Identification of two subpopulations of purified human blood B cells, CD27− CD23+and CD27high CD80+, that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6

(2008) Fabrice Cognasse et al.   IMMUNOLOGY

Role for MyD88 Signaling in Murine Gammaherpesvirus 68 Latency

(2008) L. M. Gargano et al.   JOURNAL OF VIROLOGY

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

(2008) You-Me Kim et al.   NATURE

Lack of antibody affinity maturation due to poor Toll-like receptor stimulation leads to enhanced respiratory syncytial virus disease

(2008) Maria Florencia Delgado et al.   NATURE MEDICINE

MAVS and MyD88 are essential for innate immunity but not cytotoxic T lymphocyte response against respiratory syncytial virus

(2008) V. G. Bhoj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pyogenic Bacterial Infections in Humans with MyD88 Deficiency

(2008) H. von Bernuth et al.   SCIENCE