Regulation of CD4+ T-cell polarization by suppressor of cytokine signalling proteins

Loss of Suppressor of Cytokine Signaling 1 in Helper T Cells Leads to Defective Th17 Differentiation by Enhancing Antagonistic Effects of IFN-  on STAT3 and Smads

(2014) K. Tanaka et al.   JOURNAL OF IMMUNOLOGY

Aberrant IL-4 production by SOCS3-over-expressing T cells during infection with Leishmania major exacerbates disease manifestations

(2011) M. Nakaya et al.   INTERNATIONAL IMMUNOLOGY

SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responses

(2011) Camille A. Knosp et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages

(2011) Wei Liao et al.   NATURE IMMUNOLOGY

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

(2011) Xiang-Ping Yang et al.   NATURE IMMUNOLOGY

Differentiation of Effector CD4 T Cell Populations

(2010) Jinfang Zhu et al.   Annual Review of Immunology

Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses

(2010) Li-Fan Lu et al.   CELL

Interleukin-2 inhibits polarization to T helper type 1 cells and prevents mouse acute graft-versus-host disease through up-regulating suppressors of cytokine signalling-3 expression of naive CD4+ T cells

(2010) J. Zhao et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Signal transduction pathways and transcriptional regulation in Th17 cell differentiation

(2010) Kiyoshi Hirahara et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Genetic variation in the IL7RA/IL7 pathway increases multiple sclerosis susceptibility

(2010) Rebecca L. Zuvich et al.   HUMAN GENETICS

Discrete Roles of STAT4 and STAT6 Transcription Factors in Tuning Epigenetic Modifications and Transcription during T Helper Cell Differentiation

(2010) Lai Wei et al.   IMMUNITY

Interleukin-2 Receptor Signaling: At the Interface between Tolerance and Immunity

(2010) Thomas R. Malek et al.   IMMUNITY

Diverse Targets of the Transcription Factor STAT3 Contribute to T Cell Pathogenicity and Homeostasis

(2010) Lydia Durant et al.   IMMUNITY

Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors

(2010) Jinfang Zhu et al.   IMMUNOLOGICAL REVIEWS

Increased Expression of Suppressor of Cytokine Signaling 1 mRNA in Patients With Rheumatoid Arthritis

(2010) Hua-Chen Chan et al.   KAOHSIUNG JOURNAL OF MEDICAL SCIENCES

Suppressor of cytokine signaling 1 gene expression and polymorphisms in systemic lupus erythematosus

(2010) HC Chan et al.   LUPUS

Multiple common variants for celiac disease influencing immune gene expression

(2010) Patrick C A Dubois et al.   NATURE GENETICS

Effector T cell plasticity: flexibility in the face of changing circumstances

(2010) Kenneth M Murphy et al.   NATURE IMMUNOLOGY

The enhancer HS2 critically regulates GATA-3-mediated Il4 transcription in TH2 cells

(2010) Shinya Tanaka et al.   NATURE IMMUNOLOGY

Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein

(2009) Li-Fan Lu et al.   IMMUNITY

SOCS1 negatively regulates the production of Foxp3+ CD4+ T cells in the thymus

(2009) Yifan Zhan et al.   IMMUNOLOGY AND CELL BIOLOGY

Loss of SOCS3 expression in T cells reveals a regulatory role for interleukin-17 in atherosclerosis

(2009) Soraya Taleb et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Central Role for Induced Regulatory T Cells in Tolerance Induction in Experimental Colitis

(2009) D. Haribhai et al.   JOURNAL OF IMMUNOLOGY

TGF-  Promotes Th17 Cell Development through Inhibition of SOCS3

(2009) H. Qin et al.   JOURNAL OF IMMUNOLOGY

The SOCS Box Encodes a Hierarchy of Affinities for Cullin5: Implications for Ubiquitin Ligase Formation and Cytokine Signalling Suppression

(2009) Jeffrey J. Babon et al.   JOURNAL OF MOLECULAR BIOLOGY

Suppressors of cytokine signaling (SOCS) in T cell differentiation, maturation, and function

(2009) Douglas C. Palmer et al.   TRENDS IN IMMUNOLOGY

Association between suppressors of cytokine signalling, T-helper type 1/T-helper type 2 balance and allergic sensitization in children

(2008) C. Daegelmann et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Permission to Proceed: Jak3 and STAT5 Signaling Molecules Give the Green Light for T Helper 1 Cell Differentiation

(2008) Kenneth M. Murphy   IMMUNITY

Signal Transducer and Activator of Transcription 4 Is Required for the Transcription Factor T-bet to Promote T Helper 1 Cell-Fate Determination

(2008) Vivian T. Thieu et al.   IMMUNITY

Janus-Kinase-3-Dependent Signals Induce Chromatin Remodeling at the Ifng Locus during T Helper 1 Cell Differentiation

(2008) Min Shi et al.   IMMUNITY

Interleukin-17 Promotes Autoimmunity by Triggering a Positive-Feedback Loop via Interleukin-6 Induction

(2008) Hideki Ogura et al.   IMMUNITY

Molecular Antagonism and Plasticity of Regulatory and Inflammatory T Cell Programs

(2008) Xuexian O. Yang et al.   IMMUNITY

Signal transducer and activator of transcription 4 limits the development of adaptive regulatory T cells

(2008) John T. O’Malley et al.   IMMUNOLOGY

STAT6 Inhibits TGF-β1-mediated Foxp3 Induction through Direct Binding to theFoxp3Promoter, Which Is Reverted by Retinoic Acid Receptor

(2008) Hiromi Takaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tpl2 kinase regulates T cell interferon-γ production and host resistance toToxoplasma gondii

(2008) Wendy T. Watford et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Induction and effector functions of TH17 cells

(2008) Estelle Bettelli et al.   NATURE

Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis

(2008) Andre Franke et al.   NATURE GENETICS

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS

Priming for T helper type 2 differentiation by interleukin 2–mediated induction of interleukin 4 receptor α-chain expression

(2008) Wei Liao et al.   NATURE IMMUNOLOGY

In vivo studies fail to reveal a role for IL-4 or STAT6 signaling in Th2 lymphocyte differentiation

(2008) N. van Panhuys et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA