Current best estimates for the average lifespans of mouse and human leukocytes: reviewing two decades of deuterium-labeling experiments

Human T Cell Development, Localization, and Function throughout Life

(2018) Brahma V. Kumar et al.   IMMUNITY

The fate and lifespan of human monocyte subsets in steady state and systemic inflammation

(2017) Amit A. Patel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Origin and differentiation of human memory CD8 T cells after vaccination

(2017) Rama S. Akondy et al.   NATURE

Effector CD8 T cells dedifferentiate into long-lived memory cells

(2017) Ben Youngblood et al.   NATURE

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

(2017) Alexandra-Chloé Villani et al.   SCIENCE

Plasma cell survival in the absence of B cell memory

(2017) Erika Hammarlund et al.   Nature Communications

Memory CD4 T cell subsets are kinetically heterogeneous and replenished from naive T cells at high levels

(2017) Graeme Gossel et al.   eLife

Physiologically Based Simulations of Deuterated Glucose for Quantifying Cell Turnover in Humans

(2017) Julio Lahoz-Beneytez et al.   Frontiers in Immunology

Human neutrophil kinetics: modeling of stable isotope labeling data supports short blood neutrophil half-lives

(2016) Julio Lahoz-Beneytez et al.   BLOOD

Normalizing the environment recapitulates adult human immune traits in laboratory mice

(2016) Lalit K. Beura et al.   NATURE

Human Stem Cell-like Memory T Cells Are Maintained in a State of Dynamic Flux

(2016) Raya Ahmed et al.   Cell Reports

Lymphocyte maintenance during healthy aging requires no substantial alterations in cellular turnover

(2015) Liset Westera et al.   AGING CELL

Quantification of naive and memory T-cell turnover during HIV-1 infection

(2015) Nienke Vrisekoop et al.   AIDS

Quantifying Memory CD8 T Cells Reveals Regionalization of Immunosurveillance

(2015) Elizabeth M. Steinert et al.   CELL

Differentiation Kinetics of Blood Monocytes and Dendritic Cells in Macaques: Insights to Understanding Human Myeloid Cell Development

(2015) Chie Sugimoto et al.   JOURNAL OF IMMUNOLOGY

Temporal fate mapping reveals age-linked heterogeneity in naive T lymphocytes in mice

(2015) Thea Hogan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconciling Estimates of Cell Proliferation from Stable Isotope Labeling Experiments

(2015) Raya Ahmed et al.   PLoS Computational Biology

Central Memory CD8+ T Cells Appear to Have a Shorter Lifespan and Reduced Abundance as a Function of HIV Disease Progression

(2014) K. Ladell et al.   JOURNAL OF IMMUNOLOGY

Aging and Cytomegalovirus Infection Differentially and Jointly Affect Distinct Circulating T Cell Subsets in Humans

(2014) A. M. Wertheimer et al.   JOURNAL OF IMMUNOLOGY

Human memory T cells from the bone marrow are resting and maintain long-lasting systemic memory

(2014) A. Okhrimenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diversity and clonal selection in the human T-cell repertoire

(2014) Q. Qi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Closing the gap between T-cell life span estimates from stable isotope-labeling studies in mice and humans

(2013) L. Westera et al.   BLOOD

Lineage relationship of effector and memory T cells

(2013) Nicholas P Restifo et al.   CURRENT OPINION IN IMMUNOLOGY

Virus-Specific CD4+ Memory-Phenotype T Cells Are Abundant in Unexposed Adults

(2013) Laura F. Su et al.   IMMUNITY

Whatˈs your age again? Determination of human neutrophil half-lives revisited

(2013) Tamar Tak et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Quantifying T lymphocyte turnover

(2013) Rob J. De Boer et al.   JOURNAL OF THEORETICAL BIOLOGY

Maintenance of Peripheral Naive T Cells Is Sustained by Thymus Output in Mice but Not Humans

(2012) Ineke den Braber et al.   IMMUNITY

Modelling deuterium labelling of lymphocytes with temporal and/or kinetic heterogeneity

(2012) R. J. De Boer et al.   Journal of the Royal Society Interface

Response: The in vivo half-life of human neutrophils

(2011) J. Pillay et al.   BLOOD

Deuterium and neutrophil kinetics

(2011) K. W. Li et al.   BLOOD

Doubts concerning the recently reported human neutrophil lifespan of 5.4 days

(2011) P. S. Tofts et al.   BLOOD

A human memory T cell subset with stem cell–like properties

(2011) Luca Gattinoni et al.   NATURE MEDICINE

Memory Phenotype CD4 T Cells Undergoing Rapid, Nonburst-Like, Cytokine-Driven Proliferation Can Be Distinguished from Antigen-Experienced Memory Cells

(2011) Souheil-Antoine Younes et al.   PLOS BIOLOGY

In vivo labeling with 2H2O reveals a human neutrophil lifespan of 5.4 days

(2010) J. Pillay et al.   BLOOD

Mechanisms that determine plasma cell lifespan and the duration of humoral immunity

(2010) Ian J. Amanna et al.   IMMUNOLOGICAL REVIEWS

Human cytomegalovirus-specific CD8+ T-cell expansions contain long-lived cells that retain functional capacity in both young and elderly subjects

(2010) Diana L. Wallace et al.   IMMUNOLOGY

Homeostatic Turnover of Virus-Specific Memory CD8 T Cells Occurs Stochastically and Is Independent of CD4 T Cell Help

(2010) D. K. Choo et al.   JOURNAL OF IMMUNOLOGY

Explicit Kinetic Heterogeneity: Mathematical Models for Interpretation of Deuterium Labeling of Heterogeneous Cell Populations

(2010) Vitaly V. Ganusov et al.   PLoS Computational Biology

Attrition of memory CD8 T cells

(2009) Raymond M. Welsh et al.   NATURE

Measurement of proliferation and disappearance of rapid turnover cell populations in human studies using deuterium-labeled glucose

(2009) Derek C Macallan et al.   Nature Protocols

Lymphocyte kinetics in health and disease

(2009) Becca Asquith et al.   TRENDS IN IMMUNOLOGY

Reduction of B cell turnover in chronic lymphocytic leukaemia

(2008) Julien Defoiche et al.   BRITISH JOURNAL OF HAEMATOLOGY

Memory CD8 T-cell compartment grows in size with immunological experience

(2008) Vaiva Vezys et al.   NATURE

Sparse production but preferential incorporation of recently produced naive T cells in the human peripheral pool

(2008) N. Vrisekoop et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA