The Yin and Yang of microRNAs: leukemia and immunity

Rapid Changes in MicroRNA-146a Expression Negatively Regulate the IL-1 -Induced Inflammatory Response in Human Lung Alveolar Epithelial Cells

(2014) M. M. Perry et al.   JOURNAL OF IMMUNOLOGY

microRNA Regulation of Inflammatory Responses

(2012) Ryan M. O'Connell et al.   Annual Review of Immunology

Genetic association of miRNA-146a with systemic lupus erythematosus in Europeans through decreased expression of the gene

(2012) S E Löfgren et al.   GENES AND IMMUNITY

MicroRNAs, new effectors and regulators of NF-κB

(2012) Mark P. Boldin et al.   IMMUNOLOGICAL REVIEWS

miR-146acontrols the resolution of T cell responses in mice

(2012) Lili Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

B-cell regulator of immunoglobulin heavy-chain transcription (Bright)/ARID3a is a direct target of the oncomir microRNA-125b in progenitor B-cells

(2012) M P Puissegur et al.   LEUKEMIA

Oncomir miR-125b regulates hematopoiesis by targeting the gene Lin28A

(2012) A. A. Chaudhuri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Monocyte Functional Heterogeneity by miR-146a and Relb

(2012) Martin Etzrodt et al.   Cell Reports

Molecular Pathophysiology of Myelodysplastic Syndromes

(2011) R. Coleman Lindsley et al.   Annual Review of Pathology-Mechanisms of Disease

Macrophage development from HSCs requires PU.1-coordinated microRNA expression

(2011) S. Ghani et al.   BLOOD

MicroRNA function in myeloid biology

(2011) R. M. O'Connell et al.   BLOOD

Genetic screen identifies microRNA cluster 99b/let-7e/125a as a regulator of primitive hematopoietic cells

(2011) A. Gerrits et al.   BLOOD

MicroRNA-146a Downregulates NF B Activity via Targeting TRAF6 and Functions as a Tumor Suppressor Having Strong Prognostic Implications in NK/T Cell Lymphoma

(2011) J. H. Paik et al.   CLINICAL CANCER RESEARCH

MicroRNA-146a regulates the maturation process and pro-inflammatory cytokine secretion by targeting CD40L in oxLDL-stimulated dendritic cells

(2011) Ting Chen et al.   FEBS LETTERS

MiR-146a inhibits oxidized low-density lipoprotein-induced lipid accumulation and inflammatory response via targeting toll-like receptor 4

(2011) Ke Yang et al.   FEBS LETTERS

MicroRNA 146a Expression in Rheumatoid Arthritis: Association with Tumor Necrosis Factor–Alpha and Disease Activity

(2011) Abla Abou-Zeid et al.   Genetic Testing and Molecular Biomarkers

Unraveling the Molecular Pathophysiology of Myelodysplastic Syndromes

(2011) Rafael Bejar et al.   JOURNAL OF CLINICAL ONCOLOGY

miR-146ais a significant brake on autoimmunity, myeloproliferation, and cancer in mice

(2011) Mark P. Boldin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Differential Expression of MicroRNAs in CD34+ Cells of 5q- Syndrome

(2011) Hana Votavova et al.   Journal of Hematology & Oncology

MicroRNA-125b Potentiates Macrophage Activation

(2011) Aadel A. Chaudhuri et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-146a regulates both transcription silencing and translation disruption of TNF-α during TLR4-induced gene reprogramming

(2011) Mohamed El Gazzar et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Eμ/miR-125b transgenic mice develop lethal B-cell malignancies

(2011) Y Enomoto et al.   LEUKEMIA

Deregulation of microRNAs in myelodysplastic syndrome

(2011) G W Rhyasen et al.   LEUKEMIA

NF-κB is 25

(2011) David Baltimore   NATURE IMMUNOLOGY

Distinct microRNA signatures in human lymphocyte subsets and enforcement of the naive state in CD4+ T cells by the microRNA miR-125b

(2011) Riccardo L Rossi et al.   NATURE IMMUNOLOGY

Inflammation meets cancer, with NF-κB as the matchmaker

(2011) Yinon Ben-Neriah et al.   NATURE IMMUNOLOGY

MicroRNA miR-146b-5p regulates signal transduction of TGF-β by repressing SMAD4 in thyroid cancer

(2011) M V Geraldo et al.   ONCOGENE

NF- B dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies

(2011) J. L. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Functional Variant in MicroRNA-146a Promoter Modulates Its Expression and Confers Disease Risk for Systemic Lupus Erythematosus

(2011) Xiaobing Luo et al.   PLoS Genetics

MicroRNA expression in maturing murine megakaryocytes

(2010) J. B. Opalinska et al.   BLOOD

MicroRNAs expression signatures are associated with lineage and survival in acute leukemias

(2010) Yungui Wang et al.   BLOOD CELLS MOLECULES AND DISEASES

MiR-146b-5p Suppresses EGFR Expression and ReducesIn VitroMigration and Invasion of Glioma

(2010) Mark Katakowski et al.   CANCER INVESTIGATION

Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses

(2010) Li-Fan Lu et al.   CELL

miR-146a Mediates Protective Innate Immune Tolerance in the Neonate Intestine

(2010) Cécilia Chassin et al.   Cell Host & Microbe

MicroRNA-146a disrupts hematopoietic differentiation and survival

(2010) Daniel T. Starczynowski et al.   EXPERIMENTAL HEMATOLOGY

miR-125b-2 is a potential oncomiR on human chromosome 21 in megakaryoblastic leukemia

(2010) J.-H. Klusmann et al.   GENES & DEVELOPMENT

MicroRNA-125b-1 and BLID upregulation resulting from a novel IGH translocation in childhood B-Cell precursor acute lymphoblastic leukemia

(2010) Elisa Tassano et al.   GENES CHROMOSOMES & CANCER

MicroRNA-155 Promotes Autoimmune Inflammation by Enhancing Inflammatory T Cell Development

(2010) Ryan M. O'Connell et al.   IMMUNITY

MicroRNA 125b inhibition of B cell differentiation in germinal centers

(2010) Murali Gururajan et al.   INTERNATIONAL IMMUNOLOGY

Mechanistic Role of MicroRNA-146a in Endotoxin-Induced Differential Cross-Regulation of TLR Signaling

(2010) M. A. Nahid et al.   JOURNAL OF IMMUNOLOGY

miR-146a Is Differentially Expressed by Myeloid Dendritic Cell Subsets and Desensitizes Cells to TLR2-Dependent Activation

(2010) J. Jurkin et al.   JOURNAL OF IMMUNOLOGY

A new recurrent translocation t(11;14)(q24;q32) involving IGH@ and miR-125b-1 in B-cell progenitor acute lymphoblastic leukemia

(2010) E Chapiro et al.   LEUKEMIA

Aberrant microRNA expression pattern in myelodysplastic bone marrow cells

(2010) Kais Hussein et al.   LEUKEMIA RESEARCH

Regulation of miRNA Transcription in Macrophages in Response to Candida albicans

(2010) Claire E. Monk et al.   PLoS One

MicroRNA miR-125b causes leukemia

(2010) M. Bousquet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-125b expands hematopoietic stem cells and enriches for the lymphoid-balanced and lymphoid-biased subsets

(2010) A. G. L. Ooi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output

(2010) R. M. O'Connell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA miR-125a controls hematopoietic stem cell number

(2010) S. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-146b is Highly Expressed in Adult Papillary Thyroid Carcinomas with High Risk Features Including Extrathyroidal Invasion and the BRAFV600E Mutation

(2010) Chen-Kai Chou et al.   THYROID

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

Contrast in aberrant microRNA expression in systemic lupus erythematosus and rheumatoid arthritis: Is microRNA-146 all we need?

(2009) Edward K. L. Chan et al.   ARTHRITIS AND RHEUMATISM

Expression of MicroRNA-146a in osteoarthritis cartilage

(2009) Keiichiro Yamasaki et al.   ARTHRITIS AND RHEUMATISM

MicroRNA-146a contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins

(2009) Yuanjia Tang et al.   ARTHRITIS AND RHEUMATISM

An emerging player in the adaptive immune response: microRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes

(2009) G. Curtale et al.   BLOOD

microRNA-146b inhibits glioma cell migration and invasion by targeting MMPs

(2009) Hongping Xia et al.   BRAIN RESEARCH

Divergent intracellular pathways regulate interleukin-1β-induced miR-146a and miR-146b expression and chemokine release in human alveolar epithelial cells

(2009) Mark M. Perry et al.   FEBS LETTERS

The Kinase Akt1 Controls Macrophage Response to Lipopolysaccharide by Regulating MicroRNAs

(2009) Ariadne Androulidaki et al.   IMMUNITY

miR-146a Is Critical for Endotoxin-induced Tolerance

(2009) Md A. Nahid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-146a Feedback Inhibits RIG-I-Dependent Type I IFN Production in Macrophages by Targeting TRAF6, IRAK1, and IRAK2

(2009) J. Hou et al.   JOURNAL OF IMMUNOLOGY

Identification of miR-145 and miR-146a as mediators of the 5q– syndrome phenotype

(2009) Daniel T Starczynowski et al.   NATURE MEDICINE

MicroRNA Patterns Associated with Clinical Prognostic Parameters and CNS Relapse Prediction in Pediatric Acute Leukemia

(2009) Hua Zhang et al.   PLoS One

Inositol phosphatase SHIP1 is a primary target of miR-155

(2009) R. M. O'Connell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression of microRNA-146 in rheumatoid arthritis synovial tissue

(2008) Tomoyuki Nakasa et al.   ARTHRITIS AND RHEUMATISM

Suppression of LPS-induced Interferon-  and nitric oxide in splenic lymphocytes by select estrogen-regulated microRNAs: a novel mechanism of immune modulation

(2008) R. Dai et al.   BLOOD

MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia

(2008) R. Garzon et al.   BLOOD

Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder

(2008) Ryan M. O'Connell et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Myeloid cell differentiation arrest by miR-125b-1 in myelodysplasic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation

(2008) Marina Bousquet et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis

(2008) Catherine Labbaye et al.   NATURE CELL BIOLOGY