Re-defining ERM function in lymphocyte activation and migration

Ezrin and Moesin Function Together to Promote T Cell Activation

(2014) M. H. Shaffer et al.   JOURNAL OF IMMUNOLOGY

Spatial Coupling of JNK Activation to the B Cell Antigen Receptor by Tyrosine-Phosphorylated Ezrin

(2013) N. Parameswaran et al.   JOURNAL OF IMMUNOLOGY

Ezrin and Moesin Are Required for Efficient T Cell Adhesion and Homing to Lymphoid Organs

(2013) Emily J. H. Chen et al.   PLoS One

Loss of TCR-beta F1 and/or EZRIN expression is associated with unfavorable prognosis in nodal peripheral T-cell lymphomas

(2013) S M Rodríguez-Pinilla et al.   Blood Cancer Journal

Ezrin dephosphorylation/downregulation contributes to ursolic acid-mediated cell death in human leukemia cells

(2013) G Li et al.   Blood Cancer Journal

Ezrin/Radixin/Moesin Proteins and Flotillins Cooperate to Promote Uropod Formation in T Cells

(2013) Sibylla Martinelli et al.   Frontiers in Immunology

Moesin-deficient mice reveal a non-redundant role for moesin in lymphocyte homeostasis

(2012) T. Hirata et al.   INTERNATIONAL IMMUNOLOGY

Ezrin Ubiquitylation by the E3 Ubiquitin Ligase, WWP1, and Consequent Regulation of Hepatocyte Growth Factor Receptor Activity

(2012) Rania F. Zaarour et al.   PLoS One

Constitutively active ezrin increases membrane tension, slows migration, and impedes endothelial transmigration of lymphocytes in vivo in mice

(2011) Y. Liu et al.   BLOOD

Knockdown ofezrinvia RNA interference suppressesHelicobacter pylori-enhanced invasion of gastric cancer cells

(2011) Li-Lin Fan et al.   CANCER BIOLOGY & THERAPY

The ERM protein, Ezrin, regulates neutrophil transmigration by modulating the apical localization of MRP2 in response to the SipA effector protein during Salmonella Typhimurium infection

(2011) Terence A. Agbor et al.   CELLULAR MICROBIOLOGY

Dynamic cortical actin remodeling by ERM proteins controls BCR microcluster organization and integrity

(2011) Bebhinn Treanor et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mice with Disrupted Type I Protein Kinase A Anchoring in T Cells Resist Retrovirus-Induced Immunodeficiency

(2011) R. Mosenden et al.   JOURNAL OF IMMUNOLOGY

Conformational Switching in Ezrin Regulates Morphological and Cytoskeletal Changes Required for B Cell Chemotaxis

(2011) Neetha Parameswaran et al.   JOURNAL OF IMMUNOLOGY

Proteomics Analysis of the Ezrin Interactome in B Cells Reveals a Novel Association with Myo18aα

(2011) Ken Matsui et al.   JOURNAL OF PROTEOME RESEARCH

PDZD8 is a novel moesin-interacting cytoskeletal regulatory protein that suppresses infection by herpes simplex virus type 1

(2011) Matthew S. Henning et al.   VIROLOGY

Ezrin tunes T-cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse

(2010) Rémi Lasserre et al.   EMBO JOURNAL

Spatiotemporal control of cyclic AMP immunomodulation through the PKA-Csk inhibitory pathway is achieved by anchoring to an Ezrin-EBP50-PAG scaffold in effector T cells

(2010) Isabelle Cornez et al.   FEBS LETTERS

The Membrane Skeleton Controls Diffusion Dynamics and Signaling through the B Cell Receptor

(2010) Bebhinn Treanor et al.   IMMUNITY

Organizing the cell cortex: the role of ERM proteins

(2010) Richard G. Fehon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ezrin Is Highly Expressed in Early Thymocytes, but Dispensable for T Cell Development in Mice

(2010) Meredith H. Shaffer et al.   PLoS One

The molecular assembly and organization of signaling active B-cell receptor oligomers

(2009) Pavel Tolar et al.   IMMUNOLOGICAL REVIEWS

Phospholipase C–mediated hydrolysis of PIP2 releases ERM proteins from lymphocyte membrane

(2009) Jian-Jiang Hao et al.   JOURNAL OF CELL BIOLOGY

Engagement of CD81 induces ezrin tyrosine phosphorylation and its cellular redistribution with filamentous actin

(2009) G. P. Coffey et al.   JOURNAL OF CELL SCIENCE

Phosphorylation of Ezrin/Radixin/Moesin Proteins by LRRK2 Promotes the Rearrangement of Actin Cytoskeleton in Neuronal Morphogenesis

(2009) L. Parisiadou et al.   JOURNAL OF NEUROSCIENCE

Ezrin is a key molecule in the metastasis of MOLT4 cells induced by CCL25/CCR9

(2009) Beibei Zhou et al.   LEUKEMIA RESEARCH

Ezrin mediates c-Myc actions in prostate cancer cell invasion

(2009) Y-C Chuan et al.   ONCOGENE

LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation

(2009) N. V. Belkina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early Events of B Cell Activation by Antigen

(2009) D. Depoil et al.   Science Signaling

Dysregulation of lung injury and repair in moesin-deficient mice treated with intratracheal bleomycin

(2008) Soshi Hashimoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Attenuated response to liver injury in moesin-deficient mice: Impaired stellate cell migration and decreased fibrosis

(2008) Tokunari Okayama et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

New Insights into the Early Molecular Events Underlying B Cell Activation

(2008) Naomi E. Harwood et al.   IMMUNITY

Characterization of the Ca2+-regulated Ezrin-S100P Interaction and Its Role in Tumor Cell Migration

(2008) Judith Austermann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Moesin is required for HIV-1-induced CD4-CXCR4 interaction, F-actin redistribution, membrane fusion and viral infection in lymphocytes

(2008) M. Barrero-Villar et al.   JOURNAL OF CELL SCIENCE

Enrichment of Distinct Microfilament-Associated and GTP-Binding-Proteins in Membrane/Microvilli Fractions from Lymphoid Cells

(2008) Jian-Jiang Hao et al.   JOURNAL OF PROTEOME RESEARCH