The oral mucosa immune environment and oral transmission of HIV/SIV

Early Resolution of Acute Immune Activation and Induction of PD-1 in SIV-Infected Sooty Mangabeys Distinguishes Nonpathogenic from Pathogenic Infection in Rhesus Macaques

(2014) J. D. Estes et al.   JOURNAL OF IMMUNOLOGY

Reducing infectivity of HIV upon exposure to surfaces coated withN,N-dodecyl, methyl-polyethylenimine

(2013) Stephen E. Gerrard et al.   BIOTECHNOLOGY AND BIOENGINEERING

Breast milk cellular HIV-specific interferon γ responses are associated with protection from peripartum HIV transmission

(2012) Barbara Lohman-Payne et al.   AIDS

Short Communication: HIV Type 1 Subtype C Variants Transmitted Through the Bottleneck of Breastfeeding Are Sensitive to New Generation Broadly Neutralizing Antibodies Directed Against Quaternary and CD4-Binding Site Epitopes

(2012) Elizabeth S. Russell et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Coagulation biomarkers predict disease progression in SIV-infected nonhuman primates

(2012) I. Pandrea et al.   BLOOD

Reduction of HIV-1 Load in Semen During Follow-up Study of RV144 Vaccine Trial Boosts Interest for Novel Correlates of Immune Protection in Genital Mucosa

(2012) Anna-Lena Spetz et al.   JOURNAL OF INFECTIOUS DISEASES

Determinants of Per-Coital-Act HIV-1 Infectivity Among African HIV-1–Serodiscordant Couples

(2012) James P. Hughes et al.   JOURNAL OF INFECTIOUS DISEASES

Impact of Mucosal Inflammation on Oral Simian Immunodeficiency Virus Transmission

(2012) Luis D. Giavedoni et al.   JOURNAL OF VIROLOGY

A distinct cytokine and chemokine profile at the genital mucosa is associated with HIV-1 protection among HIV-exposed seronegative commercial sex workers

(2012) J Lajoie et al.   Mucosal Immunology

Milk Matters: Soluble Toll-Like Receptor 2 (sTLR2) in Breast Milk Significantly Inhibits HIV-1 Infection and Inflammation

(2012) Bethany M. Henrick et al.   PLoS One

HIV-Specific Antibodies Capable of ADCC Are Common in Breastmilk and Are Associated with Reduced Risk of Transmission in Women with High Viral Loads

(2012) Jennifer Mabuka et al.   PLoS Pathogens

SIVmac251 Is Inefficiently Transmitted to Rhesus Macaques by Penile Inoculation with a Single SIVenv Variant Found in Ramp-up Phase Plasma

(2011) Zhong-Min Ma et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Salivary levels of antimicrobial peptides Hnp 1-3, Ll-37 and S100 in Behcet's disease

(2011) Gonca Mumcu et al.   ARCHIVES OF ORAL BIOLOGY

Cumulative Exposure to Cell-Free HIV in Breast Milk, Rather Than Feeding Pattern per se, Identifies Postnatally Infected Infants

(2011) Dorine Neveu et al.   CLINICAL INFECTIOUS DISEASES

Differential Innate Immune Responses to Low or High Dose Oral SIV Challenge in Rhesus Macaques

(2011) Andre Durudas et al.   CURRENT HIV RESEARCH

Standing Guard at the Mucosa

(2011) M. Juliana McElrath   IMMUNITY

Premastication as a Route of Pediatric HIV Transmission

(2011) Wade Ivy et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Effects of HIV-1 and Herpes Simplex Virus Type 2 Infection on Lymphocyte and Dendritic Cell Density in Adult Foreskins from Rakai, Uganda

(2011) Kristine E. Johnson et al.   JOURNAL OF INFECTIOUS DISEASES

Vaginal Langerhans Cells Nonproductively Transporting HIV-1 Mediate Infection of T Cells

(2011) L. Ballweber et al.   JOURNAL OF VIROLOGY

Mother-to-Infant Transmission of Simian Immunodeficiency Virus Is Rare in Sooty Mangabeys and Is Associated with Low Viremia

(2011) A. Chahroudi et al.   JOURNAL OF VIROLOGY

High Cell-Free Virus Load and Robust Autologous Humoral Immune Responses in Breast Milk of Simian Immunodeficiency Virus-Infected African Green Monkeys

(2011) A. B. Wilks et al.   JOURNAL OF VIROLOGY

Differential Transmission of HIV Traversing Fetal Oral/Intestinal Epithelia and Adult Oral Epithelia

(2011) S. M. Tugizov et al.   JOURNAL OF VIROLOGY

Molecular Evolution Analysis of the Human Immunodeficiency Virus Type 1 Envelope in Simian/Human Immunodeficiency Virus-Infected Macaques: Implications for Challenge Dose Selection

(2011) M. Varela et al.   JOURNAL OF VIROLOGY

Triple antiretroviral compared with zidovudine and single-dose nevirapine prophylaxis during pregnancy and breastfeeding for prevention of mother-to-child transmission of HIV-1 (Kesho Bora study): a randomised controlled trial

(2011)   LANCET INFECTIOUS DISEASES

Low levels of SIV infection in sooty mangabey central memory CD4+ T cells are associated with limited CCR5 expression

(2011) Mirko Paiardini et al.   NATURE MEDICINE

CD4+ T cells spontaneously producing human immunodeficiency virus type I in breast milk from women with or without antiretroviral drugs

(2011) Diane Valea et al.   Retrovirology

Partial efficacy of a VSV-SIV/MVA-SIV vaccine regimen against oral SIV challenge in infant macaques

(2011) Marta L. Marthas et al.   VACCINE

HIV-1 Drug Resistance Emergence among Breastfeeding Infants Born to HIV-Infected Mothers during a Single-Arm Trial of Triple-Antiretroviral Prophylaxis for Prevention of Mother-To-Child Transmission: A Secondary Analysis

(2011) Clement Zeh et al.   PLOS MEDICINE

HIV-1 exposed uninfected men who have sex with men have increased levels of salivary CC-chemokines associated with sexual behavior

(2010) Klara Hasselrot et al.   AIDS

The association between cervical human papillomavirus infection and HIV acquisition among women in Zimbabwe

(2010) Sarah H Averbach et al.   AIDS

Multiple independent lineages of HIV-1 persist in breast milk and plasma

(2010) Rebecca R Gray et al.   AIDS

Antiretroviral drugs to prevent breastfeeding HIV transmission

(2010) Lynne M Mofenson   ANTIVIRAL THERAPY

Inhibition of Human Immunodeficiency Virus Type 1 by Lactic Acid Bacteria from Human Breastmilk

(2010) Virginia Martín et al.   Breastfeeding Medicine

HIV transmission risk through anal intercourse: systematic review, meta-analysis and implications for HIV prevention

(2010) Rebecca F Baggaley et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Inactivation of Cell-Associated and Cell-Free HIV-1 by Flash-Heat Treatment of Breast Milk

(2010) Mylene L Volk et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Association between Breast Milk Erythropoietin and Reduced Risk of Mother‐to‐Child Transmission of HIV

(2010) Joanne E. Arsenault et al.   JOURNAL OF INFECTIOUS DISEASES

Relative Transmissibility of an R5 Clade C Simian‐Human Immunodeficiency Virus Across Different Mucosae in Macaques Parallels the Relative Risks of Sexual HIV‐1 Transmission in Humans via Different Routes

(2010) Agnès L. Chenine et al.   JOURNAL OF INFECTIOUS DISEASES

HIV‐Exposed Seronegative Commercial Sex Workers Show a Quiescent Phenotype in the CD4+T Cell Compartment and Reduced Expression of HIV‐Dependent Host Factors

(2010) Paul J. McLaren et al.   JOURNAL OF INFECTIOUS DISEASES

Determination of salivary levels of mucin and amylase in chronic periodontitis patients

(2010) G. A. Sánchez et al.   JOURNAL OF PERIODONTAL RESEARCH

Genetic Analyses of HIV-1envSequences Demonstrate Limited Compartmentalization in Breast Milk and Suggest Viral Replication within the Breast That Increases with Mastitis

(2010) Soren Gantt et al.   JOURNAL OF VIROLOGY

A Limited Number of Simian Immunodeficiency Virus (SIV) env Variants Are Transmitted to Rhesus Macaques Vaginally Inoculated with SIVmac251

(2010) M. Stone et al.   JOURNAL OF VIROLOGY

Low-Dose Mucosal Simian Immunodeficiency Virus Infection Restricts Early Replication Kinetics and Transmitted Virus Variants in Rhesus Monkeys

(2010) J. Liu et al.   JOURNAL OF VIROLOGY

Origin and Evolution of HIV-1 in Breast Milk Determined by Single-Genome Amplification and Sequencing

(2010) J. F. Salazar-Gonzalez et al.   JOURNAL OF VIROLOGY

Mother-to-child transmission of HIV-1 in sub-Saharan Africa: Past, present and future challenges

(2010) Taha E. Taha   LIFE SCIENCES

Restriction of HIV-1 Genotypes in Breast Milk Does Not Account for the Population Transmission Genetic Bottleneck That Occurs following Transmission

(2010) Laura Heath et al.   PLoS One

Local replication of simian immunodeficiency virus in the breast milk compartment of chronically-infected, lactating rhesus monkeys

(2010) Sallie R Permar et al.   Retrovirology

HIV is inactivated after transepithelial migration via adult oral epithelial cells but not fetal epithelial cells

(2010) Sharof M. Tugizov et al.   VIROLOGY

HIV-1 persists in breast milk cells despite antiretroviral treatment to prevent mother-to-child transmission

(2009) Dara A Lehman et al.   AIDS

Immune activation and AIDS pathogenesis

(2009) Donald L Sodora et al.   AIDS

Foreskin inflammation is associated with HIV and herpes simplex virus type-2 infections in Rakai, Uganda

(2009) Kristine E Johnson et al.   AIDS

Oral HIV-exposure elicits mucosal HIV-neutralizing antibodies in uninfected men who have sex with men

(2009) Klara Hasselrot et al.   AIDS

Comparison of HIV Type 1 Sequences from Plasma, Cell-Free Breast Milk, and Cell-Associated Breast Milk Viral Populations in Treated and Untreated Women in Mozambique

(2009) Mauro Andreotti et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Infants with late breast milk acquisition of HIV-1 generate interferon-gamma responses more rapidly than infants with early peripartum acquisition

(2009) B. Lohman-Payne et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Effect of Flash-Heat Treatment on Immunoglobulins in Breast Milk

(2009) Caroline J Chantry et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Prevention of Mother-to-Child Transmission of HIV-1 Through Breastfeeding by Treating Mothers With Triple Antiretroviral Therapy in Dar es Salaam, Tanzania: The Mitra Plus Study

(2009) Charles Kilewo et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Frequency of Gastroenteritis and Gastroenteritis-Associated Mortality With Early Weaning in HIV-1-Uninfected Children Born to HIV-Infected Women in Malawi

(2009) George Kafulafula et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1

(2009) Brandon F. Keele et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Decreased Immune Activation in Resistance to HIV‐1 Infection Is Associated with an Elevated Frequency of CD4+CD25+FOXP3+Regulatory T Cells

(2009) Catherine M. Card et al.   JOURNAL OF INFECTIOUS DISEASES

HIV‐1–Specific Cytotoxic T Lymphocytes and Breast Milk HIV‐1 Transmission

(2009) Grace C. John‐Stewart et al.   JOURNAL OF INFECTIOUS DISEASES

High Concentrations of Interleukin 15 in Breast Milk Are Associated with Protection against Postnatal HIV Transmission

(2009) Jan Walter et al.   JOURNAL OF INFECTIOUS DISEASES

Mutz-3-derived Langerhans cells are a model to study HIV-1 transmission and potential inhibitors

(2009) Marein A. W. P. de Jong et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Elevated Levels of Innate Immune Modulators in Lymph Nodes and Blood Are Associated with More-Rapid Disease Progression in Simian Immunodeficiency Virus-Infected Monkeys

(2009) A. Durudas et al.   JOURNAL OF VIROLOGY

Heterosexual risk of HIV-1 infection per sexual act: systematic review and meta-analysis of observational studies

(2009) Marie-Claude Boily et al.   LANCET INFECTIOUS DISEASES

MUC1 in human milk blocks transmission of human immunodeficiency virus from dendritic cells to T cells

(2009) Eirikur Saeland et al.   MOLECULAR IMMUNOLOGY

Glycerol monolaurate prevents mucosal SIV transmission

(2009) Qingsheng Li et al.   NATURE

Practice of Feeding Premasticated Food to Infants: A Potential Risk Factor for HIV Transmission

(2009) A. H. Gaur et al.   PEDIATRICS

Nevirapine Resistance and Breast-Milk HIV Transmission: Effects of Single and Extended-Dose Nevirapine Prophylaxis in Subtype C HIV-Infected Infants

(2009) Anitha Moorthy et al.   PLoS One

Disentangling Contributions of Reproductive Tract Infections to HIV Acquisition in African Women

(2009) Janneke H. H. M. van de Wijgert et al.   SEXUALLY TRANSMITTED DISEASES

Immunogenicity of viral vector, prime-boost SIV vaccine regimens in infant rhesus macaques: Attenuated vesicular stomatitis virus (VSV) and modified vaccinia Ankara (MVA) recombinant SIV vaccines compared to live-attenuated SIV

(2009) Koen K.A. Van Rompay et al.   VACCINE

Inflammatory Genital Infections Mitigate a Severe Genetic Bottleneck in Heterosexual Transmission of Subtype A and C HIV-1

(2009) Richard E. Haaland et al.   PLoS Pathogens

Salivary human immunodeficiency virus (HIV)-1-specific immunoglobulin A in HIV-1-exposed infants in Kenya

(2008) C. Farquhar et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Gamma/Delta T Cell mRNA Levels Decrease at Mucosal Sites and Increase at Lymphoid Sites Following an Oral SIV Infection of Macaques

(2008) David Kosub et al.   CURRENT HIV RESEARCH

Lack of viral selection in human immunodeficiency virus type 1 mother-to-child transmission with primary infection during late pregnancy and/or breastfeeding

(2008) A. Ceballos et al.   JOURNAL OF GENERAL VIROLOGY

Maternal HLA Homozygosity and Mother‐Child HLA Concordance Increase the Risk of Vertical Transmission of HIV‐1

(2008) Romel D. Mackelprang et al.   JOURNAL OF INFECTIOUS DISEASES

Trichomonas vaginalisInfection and Human Immunodeficiency Virus Acquisition in African Women

(2008) Barbara Van Der Pol et al.   JOURNAL OF INFECTIOUS DISEASES

Paucity of CD4+ CCR5+ T Cells May Prevent Transmission of Simian Immunodeficiency Virus in Natural Nonhuman Primate Hosts by Breast-Feeding

(2008) I. Pandrea et al.   JOURNAL OF VIROLOGY

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

(2008) Susan P Buchbinder et al.   LANCET

Extended-dose nevirapine to 6 weeks of age for infants to prevent HIV transmission via breastfeeding in Ethiopia, India, and Uganda: an analysis of three randomised controlled trials

(2008)   LANCET

Extended Antiretroviral Prophylaxis to Reduce Breast-Milk HIV-1 Transmission

(2008) Newton I. Kumwenda et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neutralizing monoclonal antibodies to human immunodeficiency virus type 1 do not inhibit viral transcytosis through mucosal epithelial cells

(2007) Nicolas Chomont et al.   VIROLOGY