Regulatory T cells in the central nervous system

Natural Naive CD4 + CD25 + CD127 low Regulatory T Cell (Treg) Development and Function Are Disturbed in Multiple Sclerosis Patients: Recovery of Memory Treg Homeostasis during Disease Progression

(2014) Koen Venken et al.   JOURNAL OF IMMUNOLOGY

CD2 Costimulation Reveals Defective Activity by Human CD4+CD25hi Regulatory Cells in Patients with Multiple Sclerosis

(2011) C. M. Baecher-Allan et al.   JOURNAL OF IMMUNOLOGY

The CD6 Multiple Sclerosis Susceptibility Allele Is Associated with Alterations in CD4+ T Cell Proliferation

(2011) D. M. Kofler et al.   JOURNAL OF IMMUNOLOGY

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Identification of T helper type 1–like, Foxp3+ regulatory T cells in human autoimmune disease

(2011) Margarita Dominguez-Villar et al.   NATURE MEDICINE

Intracerebral Human Regulatory T Cells: Analysis of CD4+CD25+FOXP3+ T Cells in Brain Lesions and Cerebrospinal Fluid of Multiple Sclerosis Patients

(2011) Benedikt Fritzsching et al.   PLoS One

Reduced Efficacy of Circulating Costimulatory Cells After Focal Cerebral Ischemia

(2011) Andreas Hug et al.   STROKE

Unraveling the Genetics of Autoimmunity

(2010) Lauren A. Zenewicz et al.   CELL

Haplotype 4 of the multiple sclerosis-associated interleukin-7 receptor alpha gene influences the frequency of recent thymic emigrants

(2010) B Broux et al.   GENES AND IMMUNITY

A critical role for regulatory T cell–mediated control of inflammation in the absence of commensal microbiota

(2010) Takatoshi Chinen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Prognostic significance and mechanism of Treg infiltration in human brain tumors

(2010) Joannes F.M. Jacobs et al.   JOURNAL OF NEUROIMMUNOLOGY

CD4+FoxP3+ regulatory T-cells in cerebral ischemic stroke

(2010) Xuefang Ren et al.   METABOLIC BRAIN DISEASE

Disturbed regulatory T cell homeostasis in multiple sclerosis

(2010) Koen Venken et al.   TRENDS IN MOLECULAR MEDICINE

IL-17-producing human peripheral regulatory T cells retain suppressive function

(2009) G. Beriou et al.   BLOOD

The genetics of autoimmune diseases: a networked perspective

(2009) Sergio E Baranzini   CURRENT OPINION IN IMMUNOLOGY

Loss of FOXP3 expression in natural human CD4+CD25+regulatory T cells upon repetitivein vitrostimulation

(2009) Petra Hoffmann et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Site-specific anti-tumor immunity: Differences in DC function, TGF-β production and numbers of intratumoral Foxp3+ Treg

(2009) Gregoire Biollaz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

(2009) Makoto Miyara et al.   IMMUNITY

CD4+CD25+regulatory T cells in autoimmune arthritis

(2009) Soyoung Oh et al.   IMMUNOLOGICAL REVIEWS

Cutting Edge: Responder T Cells Regulate Human DR+ Effector Regulatory T Cell Activity via Granzyme B

(2009) C. W. Ashley et al.   JOURNAL OF IMMUNOLOGY

Dynamic Development of Homing Receptor Expression and Memory Cell Differentiation of Infant CD4+CD25high Regulatory T Cells

(2009) H. Grindebacke et al.   JOURNAL OF IMMUNOLOGY

Foxp3+ regulatory T cells participate in repair of ischemic acute kidney injury

(2009) Maria Teresa Gandolfo et al.   KIDNEY INTERNATIONAL

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

(2009) Philip L De Jager et al.   NATURE GENETICS

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

(2009) Xuyu Zhou et al.   NATURE IMMUNOLOGY

Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke

(2009) Arthur Liesz et al.   NATURE MEDICINE

The role of the CD58 locus in multiple sclerosis

(2009) P. L. De Jager et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human memory FOXP3+ Tregs secrete IL-17 ex vivo and constitutively express the TH17 lineage-specific transcription factor ROR t

(2009) M. Ayyoub et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of IL-17-producing FOXP3+ regulatory T cells in humans

(2009) K. S. Voo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Infarct Volume is a Major Determiner of Post-Stroke Immune Cell Function and Susceptibility to Infection

(2009) Andreas Hug et al.   STROKE

The Spectrum of Systemic Immune Alterations After Murine Focal Ischemia

(2009) Arthur Liesz et al.   STROKE

CD4+CD25+ regulatory T cells in human lupus erythematosus

(2008) Annegret Kuhn et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Interferon Beta–Induced Restoration of Regulatory T-Cell Function in Multiple Sclerosis Is Prompted by an Increase in Newly Generated Naive Regulatory T Cells

(2008) Mirjam Korporal et al.   ARCHIVES OF NEUROLOGY

Incidence and Prognostic Impact of FoxP3+ Regulatory T Cells in Human Gliomas

(2008) A. B. Heimberger et al.   CLINICAL CANCER RESEARCH

Expansion of Human Regulatory T-Cells From Patients With Type 1 Diabetes

(2008) A. L. Putnam et al.   DIABETES

Inducible reprogramming of human T cells into Treg cells by a conditionally active form of FOXP3

(2008) Sarah E. Allan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-10 suppressor activity andex vivo Tr1 cell function are impaired in multiple sclerosis

(2008) Ivan Martinez-Forero et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human regulatory T cells and autoimmunity

(2008) Cristina M. Costantino et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Two Functional Subsets of FOXP3+ Regulatory T Cells in Human Thymus and Periphery

(2008) Tomoki Ito et al.   IMMUNITY

Regulatory T cells fail to suppress CD4+ T-bet+T cells in relapsing multiple sclerosis patients

(2008) Giovanni Frisullo et al.   IMMUNOLOGY

Multiple Sclerosis and Regulatory T Cells

(2008) Cristina Maria Costantino et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Immune activation in the peripheral blood of patients with acute ischemic stroke

(2008) Jun Yan et al.   JOURNAL OF NEUROIMMUNOLOGY

Stroke

(2008) Geoffrey A Donnan et al.   LANCET

Cancer Immunology

(2008) Olivera J. Finn   NEW ENGLAND JOURNAL OF MEDICINE

Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients

(2008) F. S. Hodi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Compromised CD4+ CD25highregulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3-positive cells and reduced FOXP3 expression at the single-cell level

(2007) Koen Venken et al.   IMMUNOLOGY

The immunology of sepsis

(2007) S Sriskandan et al.   JOURNAL OF PATHOLOGY

Generation of Potent and Stable Human CD4+ T Regulatory Cells by Activation-independent Expression of FOXP3

(2007) Sarah E Allan et al.   MOLECULAR THERAPY

Immunological responses in a patient with glioblastoma multiforme treated with sequential courses of temozolomide and immunotherapy: Case study

(2007) Amy B. Heimberger et al.   NEURO-ONCOLOGY