Through a glass less darkly: apoptosis and the germinal center response to antigen

Systematic Comparison of Gene Expression between Murine Memory and Naive B Cells Demonstrates That Memory B Cells Have Unique Signaling Capabilities

(2014) M. M. Tomayko et al.   JOURNAL OF IMMUNOLOGY

Resting Human Memory B Cells Are Intrinsically Programmed for Enhanced Survival and Responsiveness to Diverse Stimuli Compared to Naive B Cells

(2014) K. L. Good et al.   JOURNAL OF IMMUNOLOGY

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

ABT-737 is highly effective against molecular subgroups of multiple myeloma

(2011) L. Bodet et al.   BLOOD

Regulation of memory B-cell survival by the BH3-only protein Puma

(2011) C. Clybouw et al.   BLOOD

BH3-only protein Noxa regulates apoptosis in activated B cells and controls high-affinity antibody formation

(2011) F. M. Wensveen et al.   BLOOD

Identification of Molecular Vulnerabilities in Human Multiple Myeloma Cells by RNA Interference Lethality Screening of the Druggable Genome

(2011) R. E. Tiedemann et al.   CANCER RESEARCH

BCL2A1: the underdog in the BCL2 family

(2011) M Vogler   CELL DEATH AND DIFFERENTIATION

Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases

(2011) Andreas Strasser et al.   EMBO JOURNAL

SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

(2011) Hiroyuki Inuzuka et al.   NATURE

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7

(2011) Ingrid E. Wertz et al.   NATURE

Different B Cell Populations Mediate Early and Late Memory During an Endogenous Immune Response

(2011) K. A. Pape et al.   SCIENCE

Acquired resistance to ABT-737 in lymphoma cells that up-regulate MCL-1 and BFL-1

(2010) D. Yecies et al.   BLOOD

Germinal Center Dynamics Revealed by Multiphoton Microscopy with a Photoactivatable Fluorescent Reporter

(2010) Gabriel D. Victora et al.   CELL

Phase I Dose Finding Studies of Obatoclax (GX15-070), a Small Molecule Pan-BCL-2 Family Antagonist, in Patients with Advanced Solid Tumors or Lymphoma

(2010) J. J. Hwang et al.   CLINICAL CANCER RESEARCH

Mcl-1; the molecular regulation of protein function

(2010) Luke W. Thomas et al.   FEBS LETTERS

BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs

(2010) E. M. Carrington et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mcl-1 Is Essential for Germinal Center Formation and B Cell Memory

(2010) I. Vikstrom et al.   SCIENCE

An Open-Label, Multicenter, Phase I/II Study of Single-Agent AT-101 in Men with Castrate-Resistant Prostate Cancer

(2009) G. Liu et al.   CLINICAL CANCER RESEARCH

MCL-1ES, a novel variant of MCL-1, associates with MCL-1L and induces mitochondrial cell death

(2009) Jae-Hong Kim et al.   FEBS LETTERS

PLC-γ2 is essential for formation and maintenance of memory B cells

(2009) Masaki Hikida et al.   JOURNAL OF EXPERIMENTAL MEDICINE

New targets for the treatment of follicular lymphoma

(2009) Nishant Tageja et al.   Journal of Hematology & Oncology

Mcl-1 Integrates the Opposing Actions of Signaling Pathways That Mediate Survival and Apoptosis

(2009) C. Morel et al.   MOLECULAR AND CELLULAR BIOLOGY

Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival

(2009) Martin Schwickart et al.   NATURE

Multiple layers of B cell memory with different effector functions

(2009) Ismail Dogan et al.   NATURE IMMUNOLOGY

Targeting Bcl-2 family members with the BH3 mimetic AT-101 markedly enhances the therapeutic effects of chemotherapeutic agents in in vitro and in vivo models of B-cell lymphoma

(2008) L. Paoluzzi et al.   BLOOD

Down-regulation of Myeloid Cell Leukemia-1 through Inhibiting Erk/Pin 1 Pathway by Sorafenib Facilitates Chemosensitization in Breast Cancer

(2008) Q. Ding et al.   CANCER RESEARCH

R-(-)−gossypol (AT-101) activates programmed cell death in multiple myeloma cells

(2008) Michael P. Kline et al.   EXPERIMENTAL HEMATOLOGY

Fas Receptor Expression in Germinal-Center B Cells Is Essential for T and B Lymphocyte Homeostasis

(2008) Zhenyue Hao et al.   IMMUNITY

Evolution in miniature: selection, survival and distribution of antigen reactive cells in the germinal centre

(2008) David M Tarlinton   IMMUNOLOGY AND CELL BIOLOGY

ABT-263 and rapamycin act cooperatively to kill lymphoma cells in vitro and in vivo

(2008) Scott Ackler et al.   MOLECULAR CANCER THERAPEUTICS

mTORC1 promotes survival through translational control of Mcl-1

(2008) J. R. Mills et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways

(2008) G. Lenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA