Super-resolution characterization of TCR-dependent signaling clusters

Live-Cell Super-Resolution Imaging with Synthetic Fluorophores

(2012) Sebastian van de Linde et al.   Annual Review of Physical Chemistry

Functional Nanoscale Organization of Signaling Molecules Downstream of the T Cell Antigen Receptor

(2011) Eilon Sherman et al.   IMMUNITY

Dynein-Driven Transport of T Cell Receptor Microclusters Regulates Immune Synapse Formation and T Cell Activation

(2011) Akiko Hashimoto-Tane et al.   IMMUNITY

Increased Sensitivity of Antigen-Experienced T Cells through the Enrichment of Oligomeric T Cell Receptor Complexes

(2011) Rashmi Kumar et al.   IMMUNITY

The T Cell Receptor Triggering Apparatus Is Composed of Monovalent or Monomeric Proteins

(2011) John R. James et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic cortical actin remodeling by ERM proteins controls BCR microcluster organization and integrity

(2011) Bebhinn Treanor et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pre-existing clusters of the adaptor Lat do not participate in early T cell signaling events

(2011) David J Williamson et al.   NATURE IMMUNOLOGY

Probing protein heterogeneity in the plasma membrane using PALM and pair correlation analysis

(2011) Prabuddha Sengupta et al.   NATURE METHODS

Spatial Association of Signaling Proteins and F-Actin Effects on Cluster Assembly Analyzed via Photoactivation Localization Microscopy in T Cells

(2011) Chih-Jung Hsu et al.   PLoS One

Early Events in B Cell Activation

(2010) Naomi E. Harwood et al.   Annual Review of Immunology

Cooperative interactions at the SLP-76 complex are critical for actin polymerization

(2010) Mira Barda-Saad et al.   EMBO JOURNAL

The Membrane Skeleton Controls Diffusion Dynamics and Signaling through the B Cell Receptor

(2010) Bebhinn Treanor et al.   IMMUNITY

Visualizing a role for the actin cytoskeleton in the regulation of B-cell activation

(2010) Facundo D. Batista et al.   IMMUNOLOGICAL REVIEWS

PALM imaging and cluster analysis of protein heterogeneity at the cell surface

(2010) Dylan M. Owen et al.   Journal of Biophotonics

Oligomeric organization of the B-cell antigen receptor on resting cells

(2010) Jianying Yang et al.   NATURE

Dynamics of Subsynaptic Vesicles and Surface Microclusters at the Immunological Synapse

(2010) M. A. Purbhoo et al.   Science Signaling

The LAT Story: A Tale of Cooperativity, Coordination, and Choreography

(2010) L. Balagopalan et al.   Cold Spring Harbor Perspectives in Biology

ZAP-70: An Essential Kinase in T-cell Signaling

(2010) H. Wang et al.   Cold Spring Harbor Perspectives in Biology

Super-Resolution Fluorescence Microscopy

(2009) Bo Huang et al.   Annual Review of Biochemistry

The Constant Region of the Membrane Immunoglobulin Mediates B Cell-Receptor Clustering and Signaling in Response to Membrane Antigens

(2009) Pavel Tolar et al.   IMMUNITY

Hematopoietic Lineage Cell-Specific Protein 1 Is Recruited to the Immunological Synapse by IL-2-Inducible T Cell Kinase and Regulates Phospholipase C 1 Microcluster Dynamics during T Cell Spreading

(2009) E. Carrizosa et al.   JOURNAL OF IMMUNOLOGY

Ras acylation, compartmentalization and signaling nanoclusters (Review)

(2009) Yoav I. Henis et al.   MOLECULAR MEMBRANE BIOLOGY

TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation

(2009) Björn F Lillemeier et al.   NATURE IMMUNOLOGY

Taking T cells beyond the diffraction limit

(2009) P Anton van der Merwe et al.   NATURE IMMUNOLOGY

Direct observation of the nanoscale dynamics of membrane lipids in a living cell

(2008) Christian Eggeling et al.   NATURE

Actin restricts FcɛRI diffusion and facilitates antigen-induced receptor immobilization

(2008) Nicholas L. Andrews et al.   NATURE CELL BIOLOGY