CHI3L1 plays a role in cancer through enhanced production of pro-inflammatory/pro-tumorigenic and angiogenic factors

YKL-40 Is Elevated in Patients with Chronic Obstructive Pulmonary Disease and Activates Alveolar Macrophages

(2014) S. Letuve et al.   JOURNAL OF IMMUNOLOGY

YKL-40 expression could be a poor prognostic marker in the breast cancer tissue

(2013) Eun Joo Kang et al.   TUMOR BIOLOGY

Chitinase 3-like 1 Regulates Cellular and Tissue Responses via IL-13 Receptor α2

(2013) Chuan Hua He et al.   Cell Reports

Chitin microparticles for the control of intestinal inflammation

(2012) Katsuya Nagatani et al.   INFLAMMATORY BOWEL DISEASES

YKL-40 Induces IL-8 Expression from Bronchial Epithelium via MAPK (JNK and ERK) and NF- B Pathways, Causing Bronchial Smooth Muscle Proliferation and Migration

(2012) H. Tang et al.   JOURNAL OF IMMUNOLOGY

YKL-40 and MMP-9 as serum markers for patients with primary central nervous system lymphoma

(2011) Andreas F. Hottinger et al.   ANNALS OF NEUROLOGY

Breast cancer expression of YKL-40 correlates with tumour grade, poor differentiation and other cancer markers

(2011) R Shao et al.   BRITISH JOURNAL OF CANCER

Expression of the inflammatory chemokines CCL2, CCL5 and CXCL2 and the receptors CCR1–3 and CXCR2 in T lymphocytes from mammary tumor-bearing mice

(2011) Jennifer L. Owen et al.   CELLULAR IMMUNOLOGY

Induction of proinflammatory mediators by CHI3L1 is reduced by chitin treatment: Decreased tumor metastasis in a breast cancer model

(2011) Stephania Libreros et al.   INTERNATIONAL JOURNAL OF CANCER

Role of YKL-40 in the Angiogenesis, Radioresistance, and Progression of Glioblastoma

(2011) Ralph A. Francescone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conditional deletion of Stat3 in mammary epithelium impairs the acute phase response and modulates immune cell numbers during post-lactational regression

(2011) Katherine Hughes et al.   JOURNAL OF PATHOLOGY

A YKL-40-Neutralizing Antibody Blocks Tumor Angiogenesis and Progression: A Potential Therapeutic Agent in Cancers

(2011) M. Faibish et al.   MOLECULAR CANCER THERAPEUTICS

Chitinase 3-like 1 promotes macrophage recruitment and angiogenesis in colorectal cancer

(2011) M Kawada et al.   ONCOGENE

Overexpression of Chitinase 3-Like 1/YKL-40 in Lung-Specific IL-18-Transgenic Mice, Smokers and COPD

(2011) Yuki Sakazaki et al.   PLoS One

Inhibitory Activity of YKL-40 in Mammary Epithelial Cell Differentiation and Polarization Induced by Lactogenic Hormones: A Role in Mammary Tissue Involution

(2011) Steve Scully et al.   PLoS One

Chemokines and chemokine receptors: new insights into cancer-related inflammation

(2010) Gwendal Lazennec et al.   TRENDS IN MOLECULAR MEDICINE

Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13–induced tissue responses and apoptosis

(2009) Chun Geun Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

YKL-40, a secreted glycoprotein, promotes tumor angiogenesis

(2009) R Shao et al.   ONCOGENE

Potential role of chitinase 3-like-1 in inflammationassociated carcinogenic changes of epithelial cells

(2009) Katrin Eurich et al.   WORLD JOURNAL OF GASTROENTEROLOGY

YKL-40, a Marker of Simian Immunodeficiency Virus Encephalitis, Modulates the Biological Activity of Basic Fibroblast Growth Factor

(2008) Dafna Bonneh-Barkay et al.   AMERICAN JOURNAL OF PATHOLOGY

Serum YKL-40 as a marker for cervical adenocarcinoma

(2008) A. Mitsuhashi et al.   ANNALS OF ONCOLOGY

Serum YKL-40 and Interleukin 6 Levels in Hodgkin Lymphoma

(2008) R. J. Biggar et al.   CLINICAL CANCER RESEARCH

Chitinase 3-Like-1 (CHI3L1): A Putative Disease Marker at the Interface of Proteomics and Glycomics

(2008) Frederick D. Coffman   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Inflammatory bowel disease, past, present and future: lessons from animal models

(2008) Atsushi Mizoguchi et al.   JOURNAL OF GASTROENTEROLOGY

Chitinase 3-like-1 enhances bacterial adhesion to colonic epithelial cells through the interaction with bacterial chitin-binding protein

(2008) Mayumi Kawada et al.   LABORATORY INVESTIGATION

Effect of Variation inCHI3L1on Serum YKL-40 Level, Risk of Asthma, and Lung Function

(2008) Carole Ober et al.   NEW ENGLAND JOURNAL OF MEDICINE