The TRPM2 ion channel, an oxidative stress and metabolic sensor regulating innate immunity and inflammation

TRPM2 Ca2+ channel regulates energy balance and glucose metabolism

(2012) Zhiyou Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The juvenile myoclonic epilepsy-related protein EFHC1 interacts with the redox-sensitive TRPM2 channel linked to cell death

(2012) Masahiro Katano et al.   CELL CALCIUM

TRPM2 Contributes to Inflammatory and Neuropathic Pain through the Aggravation of Pronociceptive Inflammatory Responses in Mice

(2012) K. Haraguchi et al.   JOURNAL OF NEUROSCIENCE

The ion channel transient receptor potential melastatin-2 does not play a role in inflammatory mouse models of chronic obstructive pulmonary diseases

(2012) Liz Hardaker et al.   RESPIRATORY RESEARCH

Loss of glutathione homeostasis associated with neuronal senescence facilitates TRPM2 channel activation in cultured hippocampal pyramidal neurons

(2012) Jillian C Belrose et al.   Molecular Brain

Roles of TRPM2 in oxidative stress

(2011) Nobuaki Takahashi et al.   CELL CALCIUM

Dendritic cell maturation and chemotaxis is regulated by TRPM2-mediated lysosomal Ca2+ release

(2011) Adriana Sumoza-Toledo et al.   FASEB JOURNAL

Regulation of the Antimicrobial Response by NLR Proteins

(2011) Eran Elinav et al.   IMMUNITY

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Sex Differences in Neuroprotection Provided by Inhibition of TRPM2 Channels following Experimental Stroke

(2011) Jia Jia et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Expression and functional properties of TRPM2 channels in dopaminergic neurons of the substantia nigra of the rat

(2011) Kenny K. H. Chung et al.   JOURNAL OF NEUROPHYSIOLOGY

Calcium-activated non-selective cation currents are involved in generation of tonic and bursting activity in dopamine neurons of the substantia nigra pars compacta

(2011) Ana Mrejeru et al.   JOURNAL OF PHYSIOLOGY-LONDON

The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation

(2011) Anke Di et al.   NATURE IMMUNOLOGY

Transient Receptor Potential Melastatin 2 (TRPM2) ion channel is required for innate immunity against Listeria monocytogenes

(2011) H. Knowles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calcium, ischemia and excitotoxicity

(2010) Kinga Szydlowska et al.   CELL CALCIUM

Poly(ADP-ribose)glycohydrolase is an upstream regulator of Ca2+ fluxes in oxidative cell death

(2010) C. Blenn et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Identification of Direct and Indirect Effectors of the Transient Receptor Potential Melastatin 2 (TRPM2) Cation Channel

(2010) Balázs Tóth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transient Receptor Potential Melastatin 2 Is Required for Lipopolysaccharide-Induced Cytokine Production in Human Monocytes

(2010) Janine Wehrhahn et al.   JOURNAL OF IMMUNOLOGY

Transient Receptor Potential Melastatin 2 Expression is Increased Following Experimental Traumatic Brain Injury in Rats

(2010) Naomi L. Cook et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

The calcium-permeable non-selective cation channel TRPM2 is modulated by cellular acidification

(2010) John G. Starkus et al.   JOURNAL OF PHYSIOLOGY-LONDON

TRPV2 has a pivotal role in macrophage particle binding and phagocytosis

(2010) Tiffany M Link et al.   NATURE IMMUNOLOGY

TRPM2variants and bipolar disorder risk: confirmation in a family-based association study

(2009) Chun Xu et al.   BIPOLAR DISORDERS

Four Ca2+Ions Activate TRPM2 Channels by Binding in Deep Crevices near the Pore but Intracellularly of the Gate

(2009) László Csanády et al.   JOURNAL OF GENERAL PHYSIOLOGY

Modulation of TRPM2 by acidic pH and the underlying mechanisms for pH sensitivity

(2009) Jianyang Du et al.   JOURNAL OF GENERAL PHYSIOLOGY

Ca2+-dependent induction of TRPM2 currents in hippocampal neurons

(2009) Michelle E. Olah et al.   JOURNAL OF PHYSIOLOGY-LONDON

TRPM2 Functions as a Lysosomal Ca2+-Release Channel in   Cells

(2009) I. Lange et al.   Science Signaling

Emerging Roles of NAD+ and Its Metabolites in Cell Signaling

(2009) F. Koch-Nolte et al.   Science Signaling

CD38 Plays a Dual Role in Allergen-Induced Airway Hyperresponsiveness

(2008) Fabienne Gally et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Synergistic regulation of endogenous TRPM2 channels by adenine dinucleotides in primary human neutrophils

(2008) Ingo Lange et al.   CELL CALCIUM

The Poly(ADP-ribose) Polymerase PARP-1 Is Required for Oxidative Stress-induced TRPM2 Activation in Lymphocytes

(2008) Ben Buelow et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration

(2008) Shinichiro Yamamoto et al.   NATURE MEDICINE

Evolution and Function of the ADP Ribosyl Cyclase/CD38 Gene Family in Physiology and Pathology

(2008) Fabio Malavasi et al.   PHYSIOLOGICAL REVIEWS

Altered functional properties of a TRPM2 variant in Guamanian ALS and PD

(2008) M. C. Hermosura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolutionary determinants of divergent calcium selectivity of TRPM channels

(2007) Michael Mederos y Schnitzler et al.   FASEB JOURNAL