The specialized roles of immature and mature dendritic cells in antigen cross-presentation

Human Plasmacytoid Dendritic Cells Interact with gp96 via CD91 and Regulate Inflammatory Responses

(2014) A. De Filippo et al.   JOURNAL OF IMMUNOLOGY

Targeting DC-SIGN via its neck region leads to prolonged antigen residence in early endosomes, delayed lysosomal degradation, and cross-presentation

(2011) P. J. Tacken et al.   BLOOD

Antigen stored in dendritic cells after macropinocytosis is released unprocessed from late endosomes to target B cells

(2011) D. Le Roux et al.   BLOOD

CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4

(2011) Ivan Zanoni et al.   CELL

PROVENGE (Sipuleucel-T) in Prostate Cancer: The First FDA-Approved Therapeutic Cancer Vaccine

(2011) M. A. Cheever et al.   CLINICAL CANCER RESEARCH

Rab GTPases as regulators of endocytosis, targets of disease and therapeutic opportunities

(2011) JO Agola et al.   CLINICAL GENETICS

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

Design of neo-glycoconjugates that target the mannose receptor and enhance TLR-independent cross-presentation and Th1 polarization

(2011) Satwinder Kaur Singh et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Host type I IFN signals are required for antitumor CD8+T cell responses through CD8α+dendritic cells

(2011) Mercedes B. Fuertes et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Type I interferon is selectively required by dendritic cells for immune rejection of tumors

(2011) Mark S. Diamond et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TLR3-Specific Double-Stranded RNA Oligonucleotide Adjuvants Induce Dendritic Cell Cross-Presentation, CTL Responses, and Antiviral Protection

(2011) I. Jelinek et al.   JOURNAL OF IMMUNOLOGY

Plasma membrane proteomes of differentially matured dendritic cells identified by LC–MS/MS combined with iTRAQ labelling

(2011) Stéphanie Ferret-Bernard et al.   Journal of Proteomics

Efficient mucosal vaccination mediated by the neonatal Fc receptor

(2011) Lilin Ye et al.   NATURE BIOTECHNOLOGY

Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells

(2011) K. Baker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mannose receptor polyubiquitination regulates endosomal recruitment of p97 and cytosolic antigen translocation for cross-presentation

(2011) M. Zehner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The endosomal proteome of macrophage and dendritic cells

(2011) Sophie Duclos et al.   PROTEOMICS

Cross-priming CD8+ T cells by targeting antigens to human dendritic cells through DCIR

(2010) E. Klechevsky et al.   BLOOD

TLR signalling regulated antigen presentation in dendritic cells

(2010) Colin Watts et al.   CURRENT OPINION IN IMMUNOLOGY

Intracellular Toll-like Receptors

(2010) Amanda L. Blasius et al.   IMMUNITY

The Rab11a GTPase Controls Toll-like Receptor 4-Induced Activation of Interferon Regulatory Factor-3 on Phagosomes

(2010) Harald Husebye et al.   IMMUNITY

The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8α+dendritic cells

(2010) Karine Crozat et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mouse CD8α+DCs and human BDCA3+DCs are major producers of IFN-λ in response to poly IC

(2010) Henning Lauterbach et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Characterization of human DNGR-1+BDCA3+leukocytes as putative equivalents of mouse CD8α+dendritic cells

(2010) Lionel Franz Poulin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Concomitant Activation and Antigen Uptake via Human Dectin-1 Results in Potent Antigen-Specific CD8+ T Cell Responses

(2010) L. Ni et al.   JOURNAL OF IMMUNOLOGY

Antibody-Targeted NY-ESO-1 to Mannose Receptor or DEC-205 In Vitro Elicits Dual Human CD8+ and CD4+ T Cell Responses with Broad Antigen Specificity

(2010) T. Tsuji et al.   JOURNAL OF IMMUNOLOGY

TLR engagement prior to virus infection influences MHC-I antigen presentation in an epitope-dependent manner as a result of nitric oxide release

(2010) Sarah Siddiqui et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Monocyte-Derived Dendritic Cells Exhibit Increased Levels of Lysosomal Proteolysis as Compared to Other Human Dendritic Cell Populations

(2010) Nathanael McCurley et al.   PLoS One

HIV gag protein is efficiently cross-presented when targeted with an antibody towards the DEC-205 receptor in Flt3 ligand-mobilized murine DC

(2009) Leonia Bozzacco et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

C-type lectins and phagocytosis

(2009) Ann M. Kerrigan et al.   IMMUNOBIOLOGY

Co-ordinated regulation of plasmacytoid dendritic cell surface receptors upon stimulation with herpes simplex virus type 1

(2009) Philipp Schuster et al.   IMMUNOLOGY

Targeting a Mimotope Vaccine to Activating Fc  Receptors Empowers Dendritic Cells to Prime Specific CD8+ T Cell Responses in Tumor-Bearing Mice

(2009) M. Gil et al.   JOURNAL OF IMMUNOLOGY

TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88–independent TLR4 pathway

(2009) Eva M Palsson-McDermott et al.   NATURE IMMUNOLOGY

The GTPase Rab3b/3c-positive recycling vesicles are involved in cross-presentation in dendritic cells

(2009) L. Zou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antigen storage compartments in mature dendritic cells facilitate prolonged cytotoxic T lymphocyte cross-priming capacity

(2009) N. van Montfoort et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting proteins to distinct subcellular compartments reveals unique requirements for MHC class I and II presentation

(2009) R. Belizaire et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles for LPS-dependent interaction and relocation of TLR4 and TRAM in TRIF-signaling

(2008) Natsuko Tanimura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The C-type lectin surface receptor DCIR acts as a new attachment factor for HIV-1 in dendritic cells and contributes to trans- and cis-infection pathways

(2008) A. A. Lambert et al.   BLOOD

Targeting DCIR on human plasmacytoid dendritic cells results in antigen presentation and inhibits IFN-  production

(2008) F. Meyer-Wentrup et al.   BLOOD

RNA recognition and signal transduction by RIG-I-like receptors

(2008) Mitsutoshi Yoneyama et al.   IMMUNOLOGICAL REVIEWS

TLR ligand–induced podosome disassembly in dendritic cells is ADAM17 dependent

(2008) Michele A. West et al.   JOURNAL OF CELL BIOLOGY

Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling; role of CD14 and CD36

(2008) Nadra J. Nilsen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

DCIR is endocytosed into human dendritic cells and inhibits TLR8-mediated cytokine production

(2008) Friederike Meyer-Wentrup et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor

(2008) Sarah E. Ewald et al.   NATURE

Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I

(2008) Tiziana Di Pucchio et al.   NATURE IMMUNOLOGY

The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors

(2008) Yelena L Pobezinskaya et al.   NATURE IMMUNOLOGY

Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses

(2008) Maria A Ermolaeva et al.   NATURE IMMUNOLOGY

Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation

(2008) Sven Burgdorf et al.   NATURE IMMUNOLOGY

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

(2008) Jonathan C Kagan et al.   NATURE IMMUNOLOGY

Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

(2008) Boyoun Park et al.   NATURE IMMUNOLOGY

MHC Class I Endosomal and Lysosomal Trafficking Coincides with Exogenous Antigen Loading in Dendritic Cells

(2008) Genc Basha et al.   PLoS One

Regulation of Dendritic Cell Migration by CD74, the MHC Class II-Associated Invariant Chain

(2008) G. Faure-Andre et al.   SCIENCE

Cathepsin K-Dependent Toll-Like Receptor 9 Signaling Revealed in Experimental Arthritis

(2008) M. Asagiri et al.   SCIENCE

Enhanced immune stimulation by a therapeutic lymphoma tumor antigen vaccine produced in insect cells involves mannose receptor targeting to antigen presenting cells

(2008) David J. Betting et al.   VACCINE

hDectin-1 is involved in uptake and cross-presentation of cellular antigens

(2007) M. M. Weck et al.   BLOOD

Heat shock protein derivatives for delivery of antigens to antigen presenting cells

(2007) Makiya Nishikawa et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS