Molecular interactions within the IL-6/IL-12 cytokine/receptor superfamily

Crystal Structure of the Entire Ectodomain of gp130

(2010) Yibin Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for the Dual Recognition of IL-12 and IL-23 by Ustekinumab

(2010) Jinquan Luo et al.   JOURNAL OF MOLECULAR BIOLOGY

A role for IL-27p28 as an antagonist of gp130-mediated signaling

(2010) Jason S Stumhofer et al.   NATURE IMMUNOLOGY

IL-35-mediated induction of a potent regulatory T cell population

(2010) Lauren W Collison et al.   NATURE IMMUNOLOGY

IL-27 structural analysis demonstrates similarities with ciliary neurotrophic factor (CNTF) and leads to the identification of antagonistic variants

(2010) F. Rousseau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-35: odd one out or part of the family?

(2009) Lauren W. Collison et al.   IMMUNOLOGICAL REVIEWS

The IL-27 p28 Subunit Binds Cytokine-Like Factor 1 to Form a Cytokine Regulating NK and T Cell Activities Requiring IL-6R for Signaling

(2009) S. Crabe et al.   JOURNAL OF IMMUNOLOGY

IL-27 Blocks RORc Expression to Inhibit Lineage Commitment of Th17 Cells

(2009) C. Diveu et al.   JOURNAL OF IMMUNOLOGY

Advances in understanding the anti-inflammatory properties of IL-27

(2008) J.S. Stumhofer et al.   IMMUNOLOGY LETTERS

Ciliary Neurotrophic Factor, Cardiotrophin-like Cytokine, and Neuropoietin Share a Conserved Binding Site on the Ciliary Neurotrophic Factor Receptor α Chain

(2008) François Rousseau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Structure of Interleukin-23 Reveals the Molecular Basis of p40 Subunit Sharing with Interleukin-12

(2008) Patrick J. Lupardus et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal Structures of the Pro-Inflammatory Cytokine Interleukin-23 and Its Complex with a High-Affinity Neutralizing Antibody

(2008) Brian M. Beyer et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Organization of a Full-Length gp130/LIF-R Cytokine Receptor Transmembrane Complex

(2008) Georgios Skiniotis et al.   MOLECULAR CELL