Natural variation at position 45 in the D1 domain of lineage III killer cell immunoglobulin-like receptors (KIR) has major effects on the avidity and specificity for MHC class I

Humans Differ from Other Hominids in Lacking an Activating NK Cell Receptor That Recognizes the C1 Epitope of MHC Class I

(2010) A. K. Moesta et al.   JOURNAL OF IMMUNOLOGY

Coevolution of Killer Cell Ig-Like Receptors with HLA-C To Become the Major Variable Regulators of Human NK Cells

(2010) A. M. Older Aguilar et al.   JOURNAL OF IMMUNOLOGY

Human-Specific Evolution and Adaptation Led to Major Qualitative Differences in the Variable Receptors of Human and Chimpanzee Natural Killer Cells

(2010) Laurent Abi-Rached et al.   PLoS Genetics

KIR acquisition probabilities are independent of self-HLA class I ligands and increase with cellular KIR expression

(2009) S. Andersson et al.   BLOOD

KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C

(2009) Thorsten Graef et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chimpanzees Use More Varied Receptors and Ligands Than Humans for Inhibitory Killer Cell Ig-Like Receptor Recognition of the MHC-C1 and MHC-C2 Epitopes

(2009) A. K. Moesta et al.   JOURNAL OF IMMUNOLOGY

A Small, Variable, and Irregular Killer Cell Ig-Like Receptor Locus Accompanies the Absence of MHC-C and MHC-G in Gibbons

(2009) L. Abi-Rached et al.   JOURNAL OF IMMUNOLOGY

MHC class I-specific inhibitory receptors and their ligands structure diverse human NK-cell repertoires toward a balance of missing self-response

(2008) M. Yawata et al.   BLOOD

Natural killer cell recognition of missing self

(2008) Klas Kärre   NATURE IMMUNOLOGY