Journal
IMMUNITY
Volume 37, Issue 5, Pages 766-768Publisher
CELL PRESS
DOI: 10.1016/j.immuni.2012.10.013
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Funding
- Austrian Science Fund (FWF) [P 21487] Funding Source: researchfish
- Austrian Science Fund FWF [P 21487] Funding Source: Medline
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It is unclear how the Langerhans cell (LC) network is maintained in adult epidermis. In this issue of Immunity, Sere et al. (2012) show that LCs are replenished in two waves. Monocyte-derived, short-lived LCs come first. A second wave follows, and these LCs of nonmonocytic origin are long-lived.
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