Nonhuman Primate Models in the Genomic Era: A Paradigm Shift

Electroclinical phenotypes in a pedigreed baboon colony

(2013) C. Ákos Szabó et al.   EPILEPSY RESEARCH

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple Instances of Ancient Balancing Selection Shared Between Humans and Chimpanzees

(2013) E. M. Leffler et al.   SCIENCE

Baboon phylogeny as inferred from complete mitochondrial genomes

(2012) Dietmar Zinner et al.   AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY

Single-Nucleotide Polymorphisms Reveal Patterns of Allele Sharing Across the Species Boundary Between Rhesus (Macaca mulatta) and Cynomolgus (M. fascicularis) Macaques

(2012) JESSICA A. SATKOSKI TRASK et al.   AMERICAN JOURNAL OF PRIMATOLOGY

Now that We’ve Got the Map, Where Are We Going Moving from Gene Candidate Lists to Function in Studies of Brain Evolution

(2012) Chet C. Sherwood et al.   BRAIN BEHAVIOR AND EVOLUTION

Solving the lost in translation problem: Improving the effectiveness of translational research

(2012) Ceren Ergorul et al.   CURRENT OPINION IN PHARMACOLOGY

Animal Models for the Study of Hepatitis C Virus Infection and Related Liver Disease

(2012) Jens Bukh   GASTROENTEROLOGY

High-Resolution Genetic Mapping Using the Mouse Diversity Outbred Population

(2012) Karen L. Svenson et al.   GENETICS

Ten Years of the Collaborative Cross

(2012) David W. Threadgill et al.   GENETICS

A non-human primate system for large-scale genetic studies of complex traits

(2012) Anna J. Jasinska et al.   HUMAN MOLECULAR GENETICS

The Signature of Maternal Rearing in the Methylome in Rhesus Macaque Prefrontal Cortex and T Cells

(2012) N. Provencal et al.   JOURNAL OF NEUROSCIENCE

Metabolomic Phenotyping Validates the Infant Rhesus Monkey as a Model of Human Infant Metabolism

(2012) Aifric OʼSullivan et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

The diversity outbred mouse population

(2012) Gary A. Churchill et al.   MAMMALIAN GENOME

A Trans-Specific Polymorphism in ZC3HAV1 Is Maintained by Long-Standing Balancing Selection and May Confer Susceptibility to Multiple Sclerosis

(2012) R. Cagliani et al.   MOLECULAR BIOLOGY AND EVOLUTION

Phenotypic Heterogeneity of Genomic Disorders and Rare Copy-Number Variants

(2012) Santhosh Girirajan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pharmacogenomics of drug-metabolizing enzymes: a recent update on clinical implications and endogenous effects

(2012) S C Sim et al.   PHARMACOGENOMICS JOURNAL

Barriers of hepatitis C virus interspecies transmission

(2012) Lisa Sandmann et al.   VIROLOGY

Characterization of intestinal and hepatic P450 enzymes in cynomolgus monkeys with typical substrates and inhibitors for human P450 enzymes

(2012) Noriaki Yoda et al.   XENOBIOTICA

A cross-species view on viruses

(2012) Sara L Sawyer et al.   Current Opinion in Virology

Species Differences in Intestinal Metabolic Activities of Cytochrome P450 isoforms between Cynomolgus Monkeys and Humans

(2011) Haruka Nishimuta et al.   Drug Metabolism and Pharmacokinetics

Discovery of Genetic Variants in CYP1D1: Implication for Functional Integrity of CYP1D1 in Cynomolgus Macaques and Rhesus Macaques

(2011) Yasuhiro Uno et al.   Drug Metabolism and Pharmacokinetics

CYP2C76 Non-synonymous Variants in Cynomolgus and Rhesus Macaques

(2011) Shotaro Uehara et al.   Drug Metabolism and Pharmacokinetics

Macaque cytochromes P450: nomenclature, transcript, gene, genomic structure, and function

(2011) Yasuhiro Uno et al.   DRUG METABOLISM REVIEWS

Genome-based analysis of the nonhuman primate Macaca fascicularis as a model for drug safety assessment

(2011) M. Ebeling et al.   GENOME RESEARCH

Copy number variation analysis in the great apes reveals species-specific patterns of structural variation

(2011) E. Gazave et al.   GENOME RESEARCH

CYP1B1 is Polymorphic in Cynomolgus and Rhesus Macaques

(2011) Yasuhiro UNO et al.   JOURNAL OF VETERINARY MEDICAL SCIENCE

Genetic structure in a dynamic baboon hybrid zone corroborates behavioural observations in a hybrid population

(2011) M. J. E. CHARPENTIER et al.   MOLECULAR ECOLOGY

Single-Nucleotide Polymorphisms in the TNF Gene Are Associated With Obesity-Related Phenotypes in Vervet Monkeys

(2011) Stanton B. Gray et al.   Obesity

FunctionalNPYVariation as a Factor in Stress Resilience and Alcohol Consumption in Rhesus Macaques

(2010) Stephen G. Lindell et al.   ARCHIVES OF GENERAL PSYCHIATRY

The Nocturnal Bottleneck and the Evolution of Mammalian Vision

(2010) Christopher P. Heesy et al.   BRAIN BEHAVIOR AND EVOLUTION

Update Information on Drug Metabolism Systems— 2009, Part I

(2010) F. Peter Guengerich et al.   CURRENT DRUG METABOLISM

The translatability of animal models for clinical development: biomarkers and disease models

(2010) Alexandra Wendler et al.   CURRENT OPINION IN PHARMACOLOGY

The Genomic Distribution and Local Context of Coincident SNPs in Human and Chimpanzee

(2010) Alan Hodgkinson et al.   Genome Biology and Evolution

Long-term balancing selection maintains trans-specific polymorphisms in the human TRIM5 gene

(2010) R. Cagliani et al.   HUMAN GENETICS

Degeneration of Olfactory Receptor Gene Repertories in Primates: No Direct Link to Full Trichromatic Vision

(2010) A. Matsui et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genome-wide copy number variation analysis in attention-deficit/hyperactivity disorder: association with neuropeptide Y gene dosage in an extended pedigree

(2010) K-P Lesch et al.   MOLECULAR PSYCHIATRY

Animal models of neuropsychiatric disorders

(2010) Eric J Nestler et al.   NATURE NEUROSCIENCE

New perspectives on anthropoid origins

(2010) B. A. Williams et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Polymorphism and Toxicology—With Emphasis on Cytochrome P450

(2010) Inger Johansson et al.   TOXICOLOGICAL SCIENCES

Development of rostral prefrontal cortex and cognitive and behavioural disorders

(2009) Iroise Dumontheil et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Genetic Variants of CYP3A4 and CYP3A5 in Cynomolgus and Rhesus Macaques

(2009) Y. Uno et al.   DRUG METABOLISM AND DISPOSITION

Phylogeny of the macaques (Cercopithecidae: Macaca) based on Alu elements

(2009) Jing Li et al.   GENE

Identifying Heritable Brain Phenotypes in an Extended Pedigree of Vervet Monkeys

(2009) S. C. Fears et al.   JOURNAL OF NEUROSCIENCE

Strategies for performing genotype–phenotype association studies in nonhuman primates

(2009) Christina S. Barr   METHODS

Differences in DNA Methylation Patterns and Expression of the CCRK Gene in Human and Nonhuman Primate Cortices

(2009) R. Farcas et al.   MOLECULAR BIOLOGY AND EVOLUTION

Stress and disorders of the stress system

(2009) George P. Chrousos   Nature Reviews Endocrinology

Neuropeptide Y: Its multiple effects in the CNS and potential clinical significance

(2009) E. E. Benarroch   NEUROLOGY

CRH Haplotype as a Factor Influencing Cerebrospinal Fluid Levels of Corticotropin-Releasing Hormone, Hypothalamic-Pituitary-Adrenal Axis Activity, Temperament, and Alcohol Consumption in Rhesus Macaques

(2008) Christina S. Barr et al.   ARCHIVES OF GENERAL PSYCHIATRY

Analysis of copy number variation in the rhesus macaque genome identifies candidate loci for evolutionary and human disease studies

(2008) Arthur S. Lee et al.   HUMAN MOLECULAR GENETICS

Reconstructing phylogenies and phenotypes: a molecular view of human evolution

(2008) Brenda J. Bradley   JOURNAL OF ANATOMY

A natural history of the human mind: tracing evolutionary changes in brain and cognition

(2008) Chet C. Sherwood et al.   JOURNAL OF ANATOMY

Genetic variation in human NPY expression affects stress response and emotion

(2008) Zhifeng Zhou et al.   NATURE

The link between childhood trauma and depression: Insights from HPA axis studies in humans

(2008) Christine Heim et al.   PSYCHONEUROENDOCRINOLOGY

Why do we respond so differently? Reviewing determinants of human salivary cortisol responses to challenge

(2008) Brigitte M. Kudielka et al.   PSYCHONEUROENDOCRINOLOGY

The HPA axis in major depression: classical theories and new developments

(2008) Carmine M. Pariante et al.   TRENDS IN NEUROSCIENCES