Article
Acoustics
Carl Andersson
Summary: This article investigates the acoustic levitation of wavelength-sized spherical objects using a general-purpose ultrasonic transducer array and explores the possibility of extending the capabilities of such arrays to levitate multi-wavelength-sized objects. The driving signals for the array elements are determined through numerical optimization of a physics-based cost function, with simulations and experiments verifying the feasibility of levitating spheres up to 20 mm in diameter.
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA
(2022)
Article
Acoustics
Carl Andersson
Summary: This article explores the possibility of using a general-purpose ultrasonic transducer array to levitate objects of various diameters. The driving signals for the array elements are determined through numerical optimization, and the simulations are verified experimentally.
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA
(2022)
Article
Materials Science, Multidisciplinary
Menyang Gong, Xin Xu, Yupei Qiao, Zhonghan Fei, Yuanyuan Li, Jiehui Liu, Aijun He, Xiaozhou Liu
Summary: This article presents a theoretical solution for the acoustic radiation force of an arbitrary beam on spherical particles in a spherical shell structure. Finite element simulation with specific parameters was conducted using bladder and urinary calculus as a background to verify the accuracy and feasibility of the theoretical solution. The study investigates the variation of the acoustic radiation force on the particles with particle radius, incident wave spectrum, viscosity coefficient of the medium inside the spherical shell structure, and distance from the center of the particle to the center of the spherical shell structure. This scheme provides a design idea and theoretical basis for the non-contact manipulation of particles inside the spherical shell structure, with a wide range of applications in industrial and life sciences.
RESULTS IN PHYSICS
(2023)
Article
Multidisciplinary Sciences
Yuyang Gu, Viksit Kumar, E. G. Sunethra K. Dayavansha, Scott Schoen Jr, Ernest Feleppa, Rimon Tadross, Michael H. Wang, Michael J. Washburn, Kai Thomenius, Anthony E. Samir
Summary: ADAPT is an acoustic diffraction-resistant adaptive profile technology that can generate a propagation-invariant beam with high flexibility. It has applications in various fields such as medicine, biology, and material science.
Article
Acoustics
Guilherme A. Braz, Andre L. Baggio, Paulo M. Agnollitto, Felipe W. Grillo, Theo Z. Pavan, Francisco J. A. Paula, Marcello H. Nogueira-Barbosa, George C. Cardoso, Antonio A. O. Carneiro
Summary: This study proposed a new method using bursts of megahertz-frequency acoustic radiation to observe kilohertz-frequency mechanical responses in biological tissues. The correlation between spectral maps of the acquired signals and mu CT data was found to be strong. The novel technique showed good image contrast in measuring soft tissue stiffness.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2021)
Article
Acoustics
Tianquan Tang, Chao Shen, Lixi Huang
Summary: Acoustic radiation force and torque can be used for biocompatible, contact-free, and precise translation and rotation of micro-objects. By utilizing the shape asymmetry of an object, a simple standing wavefield is used to trap and rotate micro-objects. The conformal transformation approach is employed to facilitate fast analysis and real-time computer-controlled manipulation. A low-cost, simple rotational tweezing system is built to confirm the theoretical predictions.
JOURNAL OF SOUND AND VIBRATION
(2023)
Article
Engineering, Biomedical
Hsiao-Chuan Liu, Bipin Gaihre, Piotr Kijanka, Lichun Lu, Matthew W. W. Urban
Summary: Hydrogel scaffolds have become an important platform for cellular therapy and tissue engineering in regenerative medicine. However, the current standard method to characterize mechanical properties of hydrogels, called dynamic mechanical analysis (DMA), has limitations. In this study, a novel technique called acoustic force elastography microscopy (AFEM) was proposed. AFEM can evaluate the elastic properties of tissue engineering scaffolds in a non-contact and non-destructive manner, providing a promising technique for quantifying elastic properties and exploring elastic changes in cell-laden scaffolds.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2023)
Article
Multidisciplinary Sciences
Di Wu, Diego Baresch, Colin Cook, Zhichao Ma, Mengtong Duan, Dina Malounda, David Maresca, Maria P. Abundo, Justin Lee, Shirin Shivaei, David R. Mittelstein, Tian Qiu, Peer Fischer, Mikhail G. Shapiro
Summary: Ultrasound can manipulate cells with high precision through acoustic radiation force (ARF), but this ability is disconnected from cellular genetic programs due to the similar acoustic properties of most cells. Gas vesicles (GVs), a unique class of gas-filled protein nanostructures, can serve as genetically encodable actuators for selective acoustic manipulation. GVs experience strong ARF with opposite polarity to most other materials due to their lower density and higher compressibility relative to water. When expressed inside cells, GVs invert the cells' acoustic contrast and amplify their ARF, enabling selective manipulation of cells based on their genotype. GVs provide a direct link between gene expression and acoustomechanical actuation, opening up a paradigm for selective cellular control in a broad range of contexts.
Article
Acoustics
Jose Francisco Silva Costa-Junior, Joao Carlos Machado
Summary: This study aimed to identify fibrinogen concentration in plasma samples using an ultrasonic method based on impulsive acoustic radiation force, and to detect changes in plasma samples during the clot formation process. The results showed that the ultrasonic system could be clinically useful for detecting differences in peak-displacement, time of peak-displacement, and shear modulus as a function of fibrinogen concentrations.
Article
Acoustics
Jinping Wang, Feiyan Cai, Qin Lin, Degang Zhao, Hairong Zheng
Summary: In this study, the acoustic radiation force acting on spherical elastic shells in standing waves was theoretically investigated. It was found that the direction of the acoustic radiation force can be controlled by changing the physical properties of the shells, and the force can be significantly enhanced around resonant frequencies in the relatively low-frequency range.
Article
Acoustics
Thomas L. Szabo
Summary: The applications of acoustic radiation force (ARF) are expanding in various fields, but the fundamental principles behind it are still mysterious. Conflicting equations used for calculating ARF in different contexts have sparked debates for over a century. The author re-examines the physical principles behind ARF and develops more accurate equations by considering pulse shape, frequency power law attenuation, diffraction, and nonlinearity. The approach presented here settles several longstanding conflicts and provides a new framework for future ARF work.
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL
(2023)
Article
Materials Science, Multidisciplinary
Sheng Zhang, Yang Wang, Manzhu Ke, Fengming Liu, Hailong He, Liping Ye, Zhengyou Liu
Summary: Metafluids, a version of metamaterials with fluid background, have been found to accommodate a third parameter, the effective shearlike modulus. The experimental implementation of this novel metafluid, capable of supporting surface waves, updates the existing knowledge of surface waves.
Article
Health Care Sciences & Services
Masatoshi Nakamura, Shigeru Sato, Ryosuke Kiyono, Kaoru Yahata, Riku Yoshida, Taizan Fukaya, Satoru Nishishita, Andreas Konrad
Summary: This study investigated the factors associated with ankle dorsiflexion range of motion in the elderly population and found that the range of motion was significantly associated with stretch tolerance, but not with passive muscle stiffness, regardless of gender.
Article
Health Care Sciences & Services
Masatoshi Nakamura, Ryosuke Kiyono, Shigeru Sato, Kaoru Yahata, Taizan Fukaya, Satoru Nishishita, Andreas Konrad
Summary: The study did not find a significant association between shear elastic modulus of the medial gastrocnemius muscle and the rate of force development in elderly individuals. This suggests that rapid force production capacity may be related to neuromuscular function rather than muscle stiffness in older adults.
Article
Acoustics
Tianquan Tang, Lixi Huang
Summary: This study examines the acoustic forces exerted on large particles by time-harmonic waves, taking into account the scattering effects of multiple sources and particles. The results show that the contribution of scattering waves becomes significant when the size parameter is greater than 2, and increases quadratically with the amplitude parameter of the transducers. The theoretical predictions are validated through finite element simulations and applied to more complex scenarios involving multiple particles manipulated by multiple transducers.
JOURNAL OF SOUND AND VIBRATION
(2021)
Article
Engineering, Biomedical
Heechul Yoon, Stanislav Y. Emelianov
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2019)
Article
Chemistry, Multidisciplinary
Eleanor M. Donnelly, Kelsey P. Kubelick, Diego S. Dumani, Stanislav Y. Emelianov
Article
Chemistry, Multidisciplinary
Ji Hun Park, Diego S. Dumani, Ammar Arsiwala, Stanislav Emelianov, Ravi S. Kane
Article
Optics
Robin K. Hartman, Kristina A. Hallam, Eleanor M. Donnelly, Stanislav Y. Emelianov
LASER PHYSICS LETTERS
(2019)
Article
Dermatology
Timothy Sowers, Don VanderLaan, Andrei Karpiouk, Eleanor M. Donnelly, Ethan Smith, Stanislav Emelianov
LASERS IN SURGERY AND MEDICINE
(2019)
Article
Nanoscience & Nanotechnology
Yun-Sheng Chen, Yang Zhao, Soon Joon Yoon, Sanjiv Sam Gambhir, Stanislav Emelianov
NATURE NANOTECHNOLOGY
(2019)
Article
Acoustics
Yiying I. Zhu, Heechul Yoon, Andrew X. Zhao, Stanislav Y. Emelianov
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL
(2019)
Article
Computer Science, Interdisciplinary Applications
Heechul Yoon, Yiying Zhu, Steven K. Yarmoska, Stanislav Y. Emelianov
IEEE TRANSACTIONS ON MEDICAL IMAGING
(2019)
Article
Biophysics
Dragoslava P. Vekilov, Manmohan Singh, Salavat R. Aglyamov, Kirill V. Larin, K. Jane Grande-Allen
JOURNAL OF BIOMECHANICS
(2019)
Article
Optics
Manmohan Singh, Achuth Nair, Salavat R. Aglyamov, Kirin Larin
Summary: The study demonstrated the application of compression-based optical coherence elastography in measuring the biomechanical properties of the cornea under various conditions, showing a significant increase in corneal stiffness with increased IOP and corneal collagen crosslinking. The results emphasized the reliability of this technique in assessing corneal biomechanical properties and its potential for clinical applications.
Article
Optics
Hongqiu Zhang, Manmohan Singh, Achuth Nair, Kirill Larin, Salavat R. Aglyamov
Summary: The study investigated oxidative damage in cataract-induced crystalline lenses and the ability of the reductant alpha-lipoic acid (ALA) to reduce this damage. Results showed a significant increase in lens stiffness during oxidative cataract formation, with ALA demonstrating potential to reverse lens stiffening caused by oxidative damage.
Article
Engineering, Biomedical
Justin R. Rippy, Manmohan Singh, Salavat R. Aglyamov, Kirill V. Larin
Summary: This study compared ultrasound shear wave elastography (USE) and transient optical coherence elastography (OCE) and found that both methods can detect small speed changes and provide comparable measurements, showing good agreement with traditional uniaxial testing.
IEEE OPEN JOURNAL OF ENGINEERING IN MEDICINE AND BIOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Zachary D. Hood, Kelsey P. Kubelick, Kyle D. Gilroy, Don Vanderlaan, Xuan Yang, Miaoxin Yang, Miaofang Chi, Stanislav Y. Emelianov, Younan Xia
Article
Acoustics
Heechul Yoon, Geoffrey P. Luke, Stanislav Y. Emelianov
Review
Engineering, Biomedical
Timothy Sowers, Stanislav Emelianov
PHYSICS IN MEDICINE AND BIOLOGY
(2018)