Article
Chemistry, Multidisciplinary
Monica Pandey, Monika Singh, Kirti Wasnik, Shubhra Gupta, Sukanya Patra, Prem Shankar Gupta, Divya Pareek, Nyshadham Sai Naga Chaitanya, Somedutta Maity, Aramati B. M. Reddy, Ragini Tilak, Pradip Paik
Summary: In this study, mesoporous composite nanoparticles were synthesized and found to exhibit excellent antimicrobial activity against bacteria and fungi. Through computational docking methods, the interactions between the nanoparticles and microorganism-specific proteins were identified to explain their effectiveness. The composite nanoparticles show promise as stable inorganic antibiotics for use in healthcare technologies.
Article
Multidisciplinary Sciences
Ghazouan Mahmood Abdelghani, Ali Ben Ahmed, Aseel Basim Al-Zubaidi
Summary: Zinc oxide nanoparticles were synthesized by the sol-gel method and irradiated with lasers to improve their structural and functional properties. Characterization analysis revealed a hexagonal structure and a decrease in crystallite size after laser irradiation. The absorption spectra also showed a shift, indicating changes in the electronic structure. Additionally, the nanoparticles demonstrated increased antibacterial activity and improved effectiveness of antibiotics.
SCIENTIFIC REPORTS
(2022)
Article
Toxicology
Mi Ho Jeong, Yubin Han, In-Sun Oh, Dong Min Kim, Dong-Won Son, Mi-Sook Jung, Hyoseon Yang, Kyuhong Lee, Ju-Young Shin, Ha Ryong Kim, Kyu Hyuck Chung
Summary: This study evaluated the transferability, reproducibility, and predictive capacity of an in vitro acute inhalation toxicity test method, showing good consistency within and between laboratories and reliability and relevance in predicting the acute toxicity of inhalable chemicals.
TOXICOLOGY IN VITRO
(2021)
Article
Chemistry, Multidisciplinary
H. Foudi, A. Soukeur, G. Rekhila, M. Trari, M. Amara
Summary: ZnO nanoparticles were synthesized using a hydrothermal method, and the substitution effect was enhanced by introducing new compounds. The synthesized powders showed good crystallization and surface morphology in XRD and SEM analysis. In addition, the developed nanoparticles-based antibacterial paint exhibited better antibacterial effects compared to traditional paint.
Article
Biochemistry & Molecular Biology
Haixiu Wang, Eric Cox, Bert Devriendt
Summary: Enterotoxigenic Escherichia coli (ETEC) strains recognize and respond to factors secreted by gut epithelial cells, leading to transcriptional modulation of key ETEC virulence genes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Olga V. Zakharova, Valeria V. Belova, Peter A. Baranchikov, Anna A. Kostyakova, Dmitry S. Muratov, Gregory V. Grigoriev, Svetlana P. Chebotaryova, Denis V. Kuznetsov, Alexander A. Gusev
Summary: In this study, the antibacterial activity of TiS3 nanostructures in water and 0.9% NaCl solution suspensions was analyzed. The results showed that freshly prepared water solutions of TiS3 had the strongest toxicity against E. coli, but the antibacterial effect decreased significantly when the solutions were stored for 24 h or when saline solution was used instead of water. The toxicity of TiS3 in water was higher than that of TiO2 nanoparticles, but the opposite results were observed when saline solution was used. Additionally, there was no correlation between the antibacterial activity of water suspensions of nanoribbons and the stability of their colloidal systems, indicating a negligible contribution of aggregation processes to toxicity. In 0.9% NaCl solution suspensions, toxicity increased proportionally with the increase in zeta potential. It was hypothesized that the specificity of toxicity might be associated with the emission of hydrogen sulphide molecules from the surface of nanoribbons, which could either decrease or increase oxidative stress depending on the concentration. However, further investigation is needed to understand the exact underlying mechanisms. These findings highlight the importance of dispersion medium and storage period in the antibacterial activity of TiS3 nanoribbons, and have implications for nanotoxicological studies and the development of antibacterial substances and biomedical applications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Engineering, Electrical & Electronic
Anjana S. Desai, Aparna Ashok, Vaishnavi V. Dabir, Habib M. Pathan, Brajesh Pandey, Neeru Bhagat
Summary: In this study, zinc oxide nanoparticles were synthesized using a plant extract and coated on different substrates. The coating of nanoparticles improved the fire resistance property and tensile strength of the materials.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
(2023)
Article
Pharmacology & Pharmacy
Kalyanaraman Nivetha, Viswanathan Vinotha, Mohammed F. Albeshr, Shahid Mahboob, Irfan Manzoor, Marimuthu Govindarajan, Baskaralingam Vaseeharan
Summary: The present study successfully synthesized zinc oxide nanoparticles using polyphenol-rich exocarp extract of Vitis vinifera and evaluated their potential usage in various biological applications. The nanoparticles exhibited good antioxidant, antibacterial, anticancer, and larvicidal effectiveness against the Zika virus vector. Additionally, they showed decreased ecotoxicity against non-target bioindicators, indicating their wide range of biological applications.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Article
Engineering, Environmental
Thuy Thi Thanh Nguyen, Y. Ngoc Nhu Nguyen, Xuan Thanh Tran, Tam Thi Thanh Nguyen, Thuan Van Tran
Summary: Plant extract-mediated synthesis of CuONPs, ZnONPs, and CuO/ZnONPs using Annona glabra L. leaf extract can provide environmentally friendly and cost-effective nano-particles with good photocatalytic, antibacterial, and antioxidant activities.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Pharmacology & Pharmacy
Nadica Sibinovska, Simon Zakelj, Jurij Trontelj, Katja Kristan
Summary: This study tested the application of RPMI 2650 and Calu-3 cell lines for evaluating the drug permeability of nasal formulations. The results showed that these cell lines were able to discriminate the effects of different formulations on drug permeability, with good correlation to in vivo bioavailability.
Article
Multidisciplinary Sciences
Hafez Al-Momani, Dua'a Al Balawi, Saja Hamed, Borhan Aldeen Albiss, Muna Almasri, Hadeel AlGhawrie, Lujain Ibrahim, Hadeel Al Balawi, Sameer Al Haj Mahmoud, Jeffrey Pearson, Christopher Ward
Summary: In this study, the antibacterial properties of Zinc Oxide nanoparticles (ZnO NPs) were evaluated against Pseudomonas aeruginosa (PA) strains. The biosynthesized ZnO NPs were found to inhibit the growth and biofilm formation of PA strains, and reduce the expression of quorum sensing genes. The results suggest that ZnO NPs can be a potential treatment for PA and other antibiotic resistant bacteria.
SCIENTIFIC REPORTS
(2023)
Article
Chemistry, Multidisciplinary
Manna Li, Zhaofeng Chen, Lixia Yang, Jiayu Li, Jiang Xu, Chao Chen, Qiong Wu, Mengmeng Yang, Tianlong Liu
Summary: An antibacterial coating containing GO/ZnO/Cu2O was successfully sprayed on glass fibers using hydrothermal synthesis and air spraying techniques. The coating exhibited excellent antibacterial properties and stability, with a 100% antibacterial rate against E. coli and S. aureus. The photochemical activity of the coating was significantly improved, which confirmed the photocatalytic/oxidative stress mechanism.
Article
Environmental Sciences
Ankush Agrawal, Ruhani Sharma, Ankita Sharma, Kailash Chand Gurjar, Sanjay Kumar, Samit Chatterjee, Harsh Pandey, Kamlendra Awasthi, Anjali Awasthi
Summary: In this study, green synthesized zinc oxide nanoparticles (ZnO NPs) were found to exhibit excellent antibacterial and antibiofilm activity against biofilm-producing Bacillus subtilis bacteria. The nanoparticles were shown to inhibit biofilm formation and damage bacterial cell membranes, indicating their potential as an alternative treatment for biofilms and drug-resistant bacteria.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Chemistry, Physical
Han Liang, Huiyan Wang, Xuemei Sun, Wang Xu, Na Meng, Ninglin Zhou
Summary: Nanocomposites of zinc oxide nano-particles and silver nanoparticles loaded on polydopamine-modified montmorillonite demonstrated potent antibacterial ability. The synergistic effect between the two types of nanoparticles resulted in higher antimicrobial activity compared to other materials tested. The biocompatibility of the nanocomposites was also confirmed, making them promising for antibacterial applications.
APPLIED CLAY SCIENCE
(2023)
Article
Environmental Sciences
Jing Chen, Mengde Shan, Haojia Zhu, Shichuan Zhang, Jingmei Li, Leijiao Li
Summary: A BiSnSbO6-ZnO composite photocatalytic material with type II heterojunction structure was synthesized and characterized by XRD, UV-vis, and PT methods. The photocatalytic antibacterial properties of the composite were found to be significantly stronger than those of individual BiSnSbO6 and ZnO, showing broad-spectrum antibacterial activity against bacteria and fungi. The composite material generated active species OH, h(+), and e(-) through light irradiation, with e(-) playing a major role in achieving sterilization.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)