Article
Biotechnology & Applied Microbiology
Dikshita Panwar, Deepali Shrivastava, Arvind Kumar, Lavleen Kumar Gupta, N. S. Sampath Kumar, Anjani Devi Chintagunta
Summary: In this study, a quick and effective strategy for isolating exosomes from serum was investigated using antibodies coupled with gold nanoparticles. This approach could be useful for clinically monitoring the biological state of patients.
Article
Materials Science, Multidisciplinary
Mostafa Aghamirzaei, Mahmood Sowti Khiabani, Hamed Hamishehkar, Reza Rezaei Mokarram, Mohammad Amjadi
Summary: The study presents a methodology for producing high-quality gold nanoparticles from aqueous Chinese lettuce leaf extract and investigates their properties. The synthesized AuNPs exhibit good antioxidant activity and cytotoxic effects against A549 cells.
MATERIALS TODAY COMMUNICATIONS
(2021)
Review
Multidisciplinary Sciences
Ines Hammami, Nadiyah M. Alabdallah, Amjad Al Jomaa, Madiha Kamoun
Summary: In recent years, the development of nanotechnology has driven the preparation and application of gold nanoparticles, with researchers increasingly focusing on environmentally sustainable and green synthesis using non-toxic chemicals from natural sources. Gold nanoparticles have shown remarkable applications in diagnostics and therapeutics, including biosensor applications, tumor-targeting capability for cancer therapy, and precise drug delivery to diseased tissues.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2021)
Article
Pharmacology & Pharmacy
Vera Ivanovic, Danica Popovic, Sanja Petrovic, Rebeka Rudolf, Peter Majeric, Milos Lazarevic, Igor Djordjevic, Vojkan Lazic, Milena Radunovic
Summary: This study prepared a PMMA enriched with gold nanoparticles (AuNPs) and examined its physical, mechanical, and antimicrobial properties. The results showed that the density and microhardness of PMMA/AuNPs were similar to PMMA, but it exhibited better inhibitory effects on biofilm formation.
Article
Oncology
Serenella Medici, Massimiliano Peana, Donatella Coradduzza, Maria Antonietta Zoroddu
Summary: Gold nanoparticles are widely studied in biomedical applications, particularly in cancer research for early detection, diagnosis, and treatment. Despite their proven effectiveness, challenges remain in translating them into clinical practice.
SEMINARS IN CANCER BIOLOGY
(2021)
Review
Biochemical Research Methods
Girma Salale Geleta
Summary: This review summarizes the recent applications of gold nanoparticle-based colorimetric aptasensors for detecting microbial toxins, including bacterial toxins, fungal toxins, and algal toxins. Gold nanoparticles offer advantages such as easy synthesis, biocompatibility, and adjustable physicochemical properties, making them an ideal platform for constructing such biosensors. The combination of aptamers and gold nanoparticles provides a selective detection of microbial toxins. The challenges and future research opportunities in this field are also discussed.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Joanna Korpanty, Lucas R. Parent, Nathan C. Gianneschi
Summary: In the study, the radiolytic environment experienced by a polymer in water during LCTEM was examined, showing the significant mitigation effect of IPA on polymer damage and the enhancement effect of GNPs. The combination of experiments and simulations provided a generalizable strategy for assessing radiolysis mitigation or enhancement. The study highlights the caution needed for LCTEM experiments involving inorganic nanoparticles and suggests an increased use of scavengers for various LCTEM studies.
Article
Biochemical Research Methods
Xueqi Zhao, Yue Zhang, Xinghua Wang, Pinyi Ma, Daqian Song, Ying Sun
Summary: In this study, a LRSPR biosensor was developed using PDA/Ti3C2-MXene/PDA-gold film as the sensing substrate and AuNPs as enhancers. The biosensor demonstrated excellent performance with a broad detection range and low detection limit.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Physical
Moamen S. Refat, T. Altalhi, Hammad Fetooh, Amnah M. Alsuhaibani, Reham F. Hassan
Summary: This study synthesized five ceftriaxone complexes with various metal ions, characterized them, and conducted cytotoxicity experiments, showing gold(III) complex has higher toxicity against HepG-2 cells compared to HCT-116 cells.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Analytical
Nikan Momenbeitollahi, Joshua van der Zalm, Aicheng Chen, Huiyan Li
Summary: Quantifying proteins is important for understanding human health and disease, and sensitive protein quantification techniques are required for disease diagnosis. This study presents a novel signal enhancement method for fluorescence-based protein detection using gold nanoparticles on a nitrocellulose membrane. It achieved metal enhanced fluorescence and improved the sensitivity of protein quantification.
ANALYTICA CHIMICA ACTA
(2022)
Article
Biotechnology & Applied Microbiology
Ajmal Khan, Humera Jabeen, Touqeer Ahmad, Najeeb Ur Rehman, Saleha Suleman Khan, Huma Shareef, Rizwana Sarwar, Saira Yahya, Nusrat Hussain, Jalal Uddin, Javid Hussain, Ahmed Al-Harrasi
Summary: The study successfully synthesized cephradine gold nanoparticles and cephradine silver nanoparticles, with gold nanoparticles showing more activity against methicillin-resistant Staphylococcus aureus and Streptococcus mutans. These nanoparticles have the potential to be used in the treatment of diseases associated with MRSA and S. mutans.
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
(2022)
Article
Materials Science, Ceramics
Zixiang Zheng, Wei Wu, Tao Yang, Enhui Wang, Zhentao Du, Xinmei Hou, Tongxiang Liang, Hailong Wang
Summary: In this work, gold nanoparticles (AuNPs) decorated Ti3C2Tx nanosheets (MXene/AuNPs composite) were successfully fabricated through self-reduction reaction. The obtained composite exhibited uniform dispersion of 23 nm AuNPs on Ti3C2Tx nanosheets, leading to a higher specific capacitance and cyclic stability in supercapacitor applications. The composite also showed promising potential as a candidate for integrated and flexible supercapacitors.
JOURNAL OF ADVANCED CERAMICS
(2021)
Article
Biochemistry & Molecular Biology
Xuesheng Han, Alice Hirschel, Menelaos Tsapekos, Diego Perez, David Vollmer
Summary: This study provides preliminary evidence that gold nanoparticles may increase telomerase activity and slow down telomere shortening in human fibroblasts, suggesting potential anti-aging effects. However, the effects may vary in different types of fibroblasts.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Editorial Material
Geochemistry & Geophysics
Daniel D. Gregory
Summary: When the LA-ICP-MS analyses of pyrite show that the gold is held within the pyrite structure, it is often based on the observation that it plots below the gold solubility line on a gold vs. arsenic plot and exhibits relatively flat counts on laser ablation time-resolved output graphs. However, the study by Ehrig et al. (2023, this issue) demonstrates through LA-ICP-MS spot analyses, transmission electron microscopy, and electron backscatter diffraction that this interpretation is not always accurate. Additionally, they use these techniques to reveal the remobilization of trace elements, including gold, in pyrite during deformation and metamorphism.
AMERICAN MINERALOGIST
(2023)
Article
Chemistry, Multidisciplinary
Bin Zhao, Hans-Werner Becker, Sebastian Gutsch
Summary: In this study, a two-step cyclic electrochemical process is used to insert Au into PANI, resulting in the formation of Au nanoparticles whose density and size dispersion depend on the Au loading in PANI.
Article
Ecology
Abdul Arif Khan, Fozia Farooq, Sudhir K. Jain, Patrycja Golinska, Mahendra Rai
Summary: COVID-19 has caused a global catastrophe, with an increased occurrence of invasive pulmonary aspergillosis infection in patients, even in the absence of traditional risk factors. Further research is needed to explore the mechanism between SARS-CoV2 and aspergillosis in order to better address these diseases.
Article
Environmental Sciences
Pramod U. Ingle, Jayanta K. Biswas, Monojit Mondal, Mahendra K. Rai, P. Senthil Kumar, Aniket K. Gade
Summary: This study successfully synthesized silver, copper oxide, iron oxide, and alumina nanoparticles through the Moringa oleifera aqueous extract-mediated method. These nanoparticles exhibited antimicrobial activity and biofilm inhibition against various pathogens in vitro, with stronger inhibitory effects against Gram-negative bacteria. Therefore, these nanoparticles have potential for the development of alternative antimicrobials against diverse bacterial infections.
Review
Biochemistry & Molecular Biology
Paulo Wender P. Gomes, Luiza Martins, Emilli Gomes, Abraao Muribeca, Sonia Pamplona, Andrea Komesu, Carissa Bichara, Mahendra Rai, Consuelo Silva, Milton Silva
Summary: Diseases caused by viruses are a global threat and medicinal plants can be used as complementary treatments. This review explores the potential of antiviral plants from Marajo island, which show promise in combatting future viral diseases.
Editorial Material
Microbiology
Mehdi Razzaghi-Abyaneh, Zhi-Yuan Chen, Masoomeh Shams-Ghahfarokhi, Mahendra Rai
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Microbiology
Swapnil Gaikwad, Sonal Birla, Avinash P. Ingle, Aniket Gade, Pramod Ingle, Patrycja Golinska, Mahendra Rai
Summary: This study evaluated the wound-healing ability of mycofabricated silver nanoparticles and developed a novel nanogel that demonstrated excellent wound-healing activity and effectively suppressed bacterial growth on wound surfaces, providing an improved healing environment.
FRONTIERS IN MICROBIOLOGY
(2022)
Review
Biotechnology & Applied Microbiology
Mahendra Rai, Beata Zimowska, Aniket Gade, Pramod Ingle
Summary: The increasing multidrug-resistance in pathogenic microbes and the emergence of new microbial pathogens have led to the search for new antimicrobials. This review focuses on the antimicrobial potential of secondary metabolites produced by different Phoma species and the biogenic synthesis of antimicrobial silver nanoparticles from Phoma.
Article
Chemistry, Multidisciplinary
Akshay M. Pete, Pramod U. Ingle, Rajesh W. Raut, Sudhir S. Shende, Mahendra Rai, Tatiana M. Minkina, Vishnu D. Rajput, Valery P. Kalinitchenko, Aniket K. Gade
Summary: This study developed a simple method for synthesizing fluorescent nanoparticles from fruit peels. Carbon dots (CDs) were fabricated from Annona squamosa (L.) peels using a carbonization technique. The synthesized CDs were confirmed to be fluorescent and capable of being absorbed by germinating mung bean seeds, indicating their potential use as a bioimaging agent. This novel method of synthesizing CDs was found to be eco-friendly, rapid, and cost-effective.
Review
Plant Sciences
Graciela Dolores Avila-Quezada, Mahendra Rai
Summary: This article discusses the emerging role of nano-materials in the detection and treatment of Phytophthora species, including slow delivery of agrochemicals. The authors propose integrating these tools into an integrated management program to reduce pesticide use and provide more effective and sustainable control of Phytophthora pathogens.
TRENDS IN PLANT SCIENCE
(2023)
Review
Biotechnology & Applied Microbiology
Mahendra Rai, Beata Zimowska, Aniket Gade, Pramod Ingle
Summary: The genus Phoma is a major group that secretes a wide range of secondary metabolites with various bioactivities. These metabolites, including phomenon, phomin, phomodione, cytochalasins, cercosporamide, phomazines, and phomapyrone, exhibit antimicrobial, antiviral, antinematode, and anticancer activities. This review highlights the importance of Phoma fungi as a natural source of biologically active secondary metabolites and their potential as anticancer agents.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2023)
Article
Biochemical Research Methods
Jaya Lakkakula, Deepika Divakaran, Rohit Srivastava, Pramod Ingle, Aniket Gade, Rajesh Raut
Summary: Green synthesis is gaining popularity as an eco-friendly method for fabricating nanoparticles. In this study, a bioreducing agent derived from Aloe vera leaf extract was used to successfully generate silver nanoparticles within a polyvinyl alcohol matrix, resulting in a thin film with excellent antimicrobial properties for use as wound dressing materials.
IEEE TRANSACTIONS ON NANOBIOSCIENCE
(2023)
Review
Biochemistry & Molecular Biology
Fernanda Wariss Figueiredo Bezerra, Jonilson de Melo e Silva, Gustavo Guadagnucci Fontanari, Johnatt Allan Rocha de Oliveira, Mahendra Rai, Renan Campos Chiste, Luiza Helena da Silva Martins
Summary: Nanopropolis, a natural nanomaterial with various applications, including food preservation and prevention of foodborne illness, has smaller size and higher antibacterial activity compared to common propolis.
Article
Biotechnology & Applied Microbiology
Asma Saleha, Sudhir S. Shende, Pramod Ingle, Mahendra Rai, Tatiana M. Minkina, Aniket Gade
Summary: Antimicrobial resistance (AMR) is a global public health issue, and there is a need for new bactericides. This study investigates the antimicrobial activity of Mentha piperita L. leaf extract-produced zinc oxide nanoparticles (ZnONPs). The combination of ZnONPs and Kanamycin (KAN) demonstrates improved antibacterial activity against resistant bacteria and reduces the minimum inhibitory concentration (MIC) of KAN.
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
(2023)
Review
Chemistry, Physical
Szymon Graczyk, Robert Paslawski, Arkadiusz Grzeczka, Urszula Paslawska, Beata Swieczko-Zurek, Klaudia Malisz, Ketul Popat, Alina Sionkowska, Patrycja Golinska, Mahendra Rai
Summary: Microbial colonization in veterinary stents is a significant issue in veterinary medicine. Prolonged colonization can lead to infections, inflammation, and compromise the effectiveness of the stents, affecting the overall well-being of animal patients. Managing and mitigating the impact of these pathogens is a crucial challenge that veterinarians and researchers are actively addressing.
Review
Green & Sustainable Science & Technology
Roshan M. Shinde, Pramod U. Ingle, Hemangi R. Trivedi, Dhiraj Wasule, Anjali Gaharwar, Aniket K. Gade, Mahendra Rai, Suvendu Manna, Prashant K. Srivastava, Jayanta K. Biswas
Summary: Water is essential for life on Earth and is used in everyday activities as well as major industrial applications. However, anthropogenic activities, such as agriculture and the textile industry, are leading to the release of harmful chemical effluents and dyes into water bodies, causing pollution and harm to the environment. Various remediation methods, including physical-chemical and biological methods, are being used, with a focus on bioremediation using microbes, algae, yeasts, enzymes, and plants. Remote sensing and GIS are being used for real-time management and maintenance of water quality.
ENVIRONMENT DEVELOPMENT AND SUSTAINABILITY
(2023)