4.7 Article

Hamilton-Jacobi skeleton on cortical surfaces

Journal

IEEE TRANSACTIONS ON MEDICAL IMAGING
Volume 27, Issue 5, Pages 664-673

Publisher

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TMI.2007.913279

Keywords

cortex; folding pattern; graphical representation; skeleton; triangular mesh

Funding

  1. NCRR NIH HHS [U54 RR021813-02, U54 RR021813-01, U54 RR021813] Funding Source: Medline

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In this paper, we propose a new method to construct graphical representations of cortical folding patterns by computing skeletons on triangulated cortical surfaces. In our approach, a cortical surface is first partitioned into sulcal and gyral regions via the solution of a variational problem using graph cuts, which can guarantee global optimality. After that, we extend the method of Hamilton-Jacobi skeleton [1] to subsets of triangulated surfaces, together with a geometrically intuitive pruning process that can trade off between skeleton complexity and the completeness of representing folding patterns. Compared with previous work that uses skeletons of 3-D volumes to represent sulcal patterns, the skeletons on cortical surfaces can be easily decomposed into branches and provide a simpler way to construct graphical representations of cortical morphometry. In our experiments, we demonstrate our method on two different cortical surface models, its ability of capturing major sulcal patterns and its application to compute skeletons of gyral regions.

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