Potential Threats Posed by New or Emerging Marine Biotoxins in UK Waters and Examination of Detection Methodologies Used for Their Control: Cyclic Imines

Distribution of Marine Lipophilic Toxins in Shellfish Products Collected from the Chinese Market

(2015) Haiyan Wu et al.   Marine Drugs

The Neurotoxic Effect of 13,19-Didesmethyl and 13-Desmethyl Spirolide C Phycotoxins Is Mainly Mediated by Nicotinic Rather Than Muscarinic Acetylcholine Receptors

(2015) Romulo Aráoz et al.   TOXICOLOGICAL SCIENCES

Differences in the toxin profiles of Alexandrium ostenfeldii (Dinophyceae) strains isolated from different geographic origins: Evidence of paralytic toxin, spirolide, and gymnodimine

(2015) Pablo Salgado et al.   TOXICON

Confirmation of Pinnatoxins and Spirolides in Shellfish and Passive Samplers from Catalonia (Spain) by Liquid Chromatography Coupled with Triple Quadrupole and High-Resolution Hybrid Tandem Mass Spectrometry

(2014) María García-Altares et al.   Marine Drugs

Pinnatoxin H: a new pinnatoxin analogue from a South China Sea Vulcanodinium rugosum isolate

(2014) Andrew I. Selwood et al.   TETRAHEDRON LETTERS

12. Development and validation of a colorimetric microtiter plate based receptor-binding assays for the determination of freshwater and marine toxins using the nicotinic cholinergic receptor

(2014) F. Rubio et al.   TOXICON

Vulcanodinium rugosumgen. et sp. nov. (Dinophyceae), un Nouveau Dinoflagellé Marin de la Côte Méditerranéenne Française

(2013) Elisabeth Nézan et al.   CRYPTOGAMIE ALGOLOGIE

Benefit of 13-desmethyl Spirolide C Treatment in Triple Transgenic Mouse Model of Alzheimer Disease: Beta-Amyloid and Neuronal Markers Improvement

(2013) Eva Alonso et al.   Current Alzheimer Research

Paralytic shellfish toxins or spirolides? The role of environmental and genetic factors in toxin production of the Alexandrium ostenfeldii complex

(2013) Sanna Suikkanen et al.   HARMFUL ALGAE

Variability of paralytic shellfish toxin occurrence and profiles in bivalve molluscs from Great Britain from official control monitoring as determined by pre-column oxidation liquid chromatography and implications for applying immunochemical tests

(2013) Andrew D. Turner et al.   HARMFUL ALGAE

Phylogenetic relationships, morphological variation, and toxin patterns in theAlexandrium ostenfeldii(Dinophyceae) complex: implications for species boundaries and identities

(2013) Anke Kremp et al.   JOURNAL OF PHYCOLOGY

Identification and quantification of toxic and nontoxic strains of the harmful dinoflagellateAlexandrium tamarenseusing fluorescence in situ hybridization and flow cytometry

(2013) Lisa K. Eckford-Soper et al.   LIMNOLOGY AND OCEANOGRAPHY-METHODS

Discovery of gymnodimine fatty acid ester metabolites in shellfish using liquid chromatography/mass spectrometry

(2013) P. de la Iglesia et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Portimine: a bioactive metabolite from the benthic dinoflagellate Vulcanodinium rugosum

(2013) Andrew I. Selwood et al.   TETRAHEDRON LETTERS

Pinnatoxin G is responsible for atypical toxicity in mussels (Mytilus galloprovincialis) and clams (Venerupis decussata) from Ingril, a French Mediterranean lagoon

(2013) Philipp Hess et al.   TOXICON

Coupling the Torpedo Microplate-Receptor Binding Assay with Mass Spectrometry to Detect Cyclic Imine Neurotoxins

(2012) Rómulo Aráoz et al.   ANALYTICAL CHEMISTRY

Spirolide uptake and detoxification by Crassostrea gigas exposed to the toxic dinoflagellate Alexandrium ostenfeldii

(2012) Walid Medhioub et al.   AQUACULTURE

Coastal ship traffic: a significant introduction vector for potentially harmful dinoflagellates in eastern Canada

(2012) Suzanne Roy et al.   CANADIAN JOURNAL OF FISHERIES AND AQUATIC SCIENCES

Alexandrium peruvianum (Balech and Mendiola) Balech and Tangen a new toxic species for coastal North Carolina

(2012) Carmelo R. Tomas et al.   HARMFUL ALGAE

Prevalence and persistence of gymnodimines in clams from the Gulf of Gabes (Tunisia) studied by mouse bioassay and LC–MS/MS

(2012) Idriss Ben Naila et al.   HARMFUL ALGAE

Identification of Pinnatoxins and Discovery of Their Fatty Acid Ester Metabolites in Mussels (Mytilus edulis) from Eastern Canada

(2012) Pearse McCarron et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The first report ofVulcanodinium rugosum(Dinophyceae) from the South China Sea with a focus on the life cycle

(2012) N Zeng et al.   NEW ZEALAND JOURNAL OF MARINE AND FRESHWATER RESEARCH

Acute toxicity of pinnatoxins E, F and G to mice

(2012) Rex Munday et al.   TOXICON

First direct fluorescence polarization assay for the detection and quantification of spirolides in mussel samples

(2011) Paz Otero et al.   ANALYTICA CHIMICA ACTA

Solid-Phase Receptor-Based Assay for the Detection of Cyclic Imines by Chemiluminescence, Fluorescence, or Colorimetry

(2011) Laura P. Rodríguez et al.   ANALYTICAL CHEMISTRY

Pharmacokinetic and toxicological data of spirolides after oral and intraperitoneal administration

(2011) Paz Otero et al.   FOOD AND CHEMICAL TOXICOLOGY

New perspectives on biotoxin detection in Rangaunu Harbour, New Zealand arising from the discovery of pinnatoxins

(2011) P.S. McNabb et al.   HARMFUL ALGAE

The globally distributed genus Alexandrium: Multifaceted roles in marine ecosystems and impacts on human health

(2011) Donald M. Anderson et al.   HARMFUL ALGAE

Total Synthesis of Pinnatoxins A and G and Revision of the Mode of Action of Pinnatoxin A

(2011) Romulo Araoz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dinoflagellate Vulcanodinium rugosum identified as the causative organism of pinnatoxins in Australia, New Zealand and Japan

(2011) Lesley Rhodes et al.   PHYCOLOGIA

Occurrence of 12-methylgymnodimine in a spirolide-producing dinoflagellate Alexandrium peruvianum and the biogenetic implications

(2011) Ryan M. Van Wagoner et al.   TETRAHEDRON LETTERS

13-Desmethyl spirolide-c and 13,19-didesmethyl spirolide-c trans-epithelial permeabilities: Human intestinal permeability modelling

(2011) Begoña Espiña et al.   TOXICOLOGY

Pinnatoxins and spirolides in Norwegian blue mussels and seawater

(2011) Thomas Rundberget et al.   TOXICON

Investigations into the Toxicology of Spirolides, a Group of Marine Phycotoxins

(2011) Rex Munday et al.   Toxins

Detection of 13,19-didesmethyl C spirolide by fluorescence polarization using Torpedo electrocyte membranes

(2010) Eva S. Fonfría et al.   ANALYTICAL BIOCHEMISTRY

Distribution, diversity and toxin composition of the genusAlexandrium(Dinophyceae) in Scottish waters

(2010) Lyndsay Brown et al.   EUROPEAN JOURNAL OF PHYCOLOGY

Production of pinnatoxins by a peridinoid dinoflagellate isolated from Northland, New Zealand

(2010) L. Rhodes et al.   HARMFUL ALGAE

Isolation, Structural Determination and Acute Toxicity of Pinnatoxins E, F and G

(2010) Andrew I. Selwood et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism

(2010) Y. Bourne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Co-Occurrence of the West European (Gr.III) and North American (Gr.I) Ribotypes of Alexandrium tamarense (Dinophyceae) in Shetland, Scotland

(2010) Nicolas Touzet et al.   PROTIST

Characterization of 27-hydroxy-13-desmethyl spirolide C and 27-oxo-13,19-didesmethyl spirolide C. Further insights into the complex Adriatic Alexandrium ostenfeldii toxin profile

(2010) Patrizia Ciminiello et al.   TOXICON

Confirmed identification of gymnodimine in oysters from the west coast of South Africa by liquid chromatography–tandem mass spectrometry

(2009) B Krock et al.   AFRICAN JOURNAL OF MARINE SCIENCE

Feasibility of gymnodimine and 13-desmethyl C spirolide detection by fluorescence polarization using a receptor-based assay in shellfish matrixes

(2009) Eva S. Fonfría et al.   ANALYTICA CHIMICA ACTA

Solid phase extraction for removal of matrix effects in lipophilic marine toxin analysis by liquid chromatography-tandem mass spectrometry

(2009) Arjen Gerssen et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Detection of Gymnodimine-A and 13-Desmethyl C Spirolide Phycotoxins by Fluorescence Polarization

(2009) Natalia Vilariño et al.   ANALYTICAL CHEMISTRY

Dynamics of co-occurring Alexandrium minutum (Global Clade) and A. tamarense (West European) (Dinophyceae) during a summer bloom in Cork Harbour, Ireland (2006)

(2009) N. Touzet et al.   DEEP-SEA RESEARCH PART II-TOPICAL STUDIES IN OCEANOGRAPHY

Detoxification enhancement in the gymnodimine-contaminated grooved carpet shell, Ruditapes decussatus (Linné)

(2009) Medhioub Walid et al.   HARMFUL ALGAE

Liquid chromatography–tandem mass spectrometry method for the detection of marine lipophilic toxins under alkaline conditions

(2009) Arjen Gerssen et al.   JOURNAL OF CHROMATOGRAPHY A

Characterization of a Dispiroketal Spirolide Subclass fromAlexandrium ostenfeldii

(2009) Joy S. Roach et al.   JOURNAL OF NATURAL PRODUCTS

Quantitative Determination of Gymnodimine-A by High Performance Liquid Chromatography in Contaminated Clams from Tunisia Coastline

(2009) Riadh Marrouchi et al.   MARINE BIOTECHNOLOGY

First identification of azaspiracid and spirolides in Mesodesma donacium and Mulinia edulis from Northern Chile

(2009) Gonzalo Álvarez et al.   TOXICON

Toxic dinoflagellates (Dinophyceae) from Rarotonga, Cook Islands

(2009) Lesley L. Rhodes et al.   TOXICON

PSP toxin analysis and discrimination of the naturally co-occurring Alexandrium tamarense and A. minutum (Dinophyceae) in Cork Harbour, Ireland

(2008) N Touzet et al.   AQUATIC MICROBIAL ECOLOGY

Morphogenetic diversity and biotoxin composition of Alexandrium (Dinophyceae) in Irish coastal waters

(2008) Nicolas Touzet et al.   HARMFUL ALGAE

Uptake of paralytic shellfish poisoning and spirolide toxins by paddle crabs (Ovalipes catharus) via a bivalve vector

(2008) Rozalind Jester et al.   HARMFUL ALGAE

The marine phycotoxin gymnodimine targets muscular and neuronal nicotinic acetylcholine receptor subtypes with high affinity

(2008) Riadh Kharrat et al.   JOURNAL OF NEUROCHEMISTRY

Are spirolides converted in biological systems?—A study

(2007) Bernd Christian et al.   TOXICON