Activation of the Tumor Suppressor PP2A Emerges as a Potential Therapeutic Strategy for Treating Prostate Cancer
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Title
Activation of the Tumor Suppressor PP2A Emerges as a Potential Therapeutic Strategy for Treating Prostate Cancer
Authors
Keywords
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Journal
Marine Drugs
Volume 13, Issue 6, Pages 3276-3286
Publisher
MDPI AG
Online
2015-05-27
DOI
10.3390/md13063276
References
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Note: Only part of the references are listed.- Erratum to: CIP2A mediates prostate cancer progression via the c-MYC signaling pathway
- (2015) Zexiong Guo et al. TUMOR BIOLOGY
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- Restoration of PPP2CA expression reverses epithelial-to-mesenchymal transition and suppresses prostate tumour growth and metastasis in an orthotopic mouse model
- (2014) A Bhardwaj et al. BRITISH JOURNAL OF CANCER
- Targeting Inhibitors of the Tumor Suppressor PP2A for the Treatment of Pancreatic Cancer
- (2014) Amy S. Farrell et al. MOLECULAR CANCER RESEARCH
- PP2A Inhibition Is a Common Event in Colorectal Cancer and Its Restoration Using FTY720 Shows Promising Therapeutic Potential
- (2014) I. Cristobal et al. MOLECULAR CANCER THERAPEUTICS
- Knockdown of cancerous inhibitor of protein phosphatase 2A may sensitize metastatic castration-resistant prostate cancer cells to cabazitaxel chemotherapy
- (2014) Jinming Huang et al. TUMOR BIOLOGY
- Deregulation of the phosphatase, PP2A is a common event in breast cancer, predicting sensitivity to FTY720
- (2014) Shawn Baldacchino et al. EPMA Journal
- Impaired expression of protein phosphatase 2A subunits enhances metastatic potential of human prostate cancer cells through activation of AKT pathway
- (2013) P Pandey et al. BRITISH JOURNAL OF CANCER
- Protein phosphatase 2A: a target for anticancer therapy
- (2013) Danilo Perrotti et al. LANCET ONCOLOGY
- PPP2R2C Loss Promotes Castration-Resistance and Is Associated with Increased Prostate Cancer-Specific Mortality
- (2013) Eric G. Bluemn et al. MOLECULAR CANCER RESEARCH
- Carnosic acid modulates Akt/IKK/NF-κB signaling by PP2A and induces intrinsic and extrinsic pathway mediated apoptosis in human prostate carcinoma PC-3 cells
- (2012) Susanta Kar et al. APOPTOSIS
- Zoledronic acid in combination with serine/threonine phosphatase inhibitors induces enhanced cytotoxicity and apoptosis in hormone-refractory prostate cancer cell lines by decreasing the activities of PP1 and PP2A
- (2012) Yalcin Cirak et al. BJU INTERNATIONAL
- The sphingosine kinase inhibitor 2-(p-hyroxyanilino)-4-(p-chlorophenyl)thiazole reduces androgen receptor expression via an oxidative stress-dependent mechanism
- (2012) Francesca Tonelli et al. BRITISH JOURNAL OF PHARMACOLOGY
- Demethoxycurcumin Modulates Prostate Cancer Cell Proliferation via AMPK-Induced Down-regulation of HSP70 and EGFR
- (2012) Chao-Ming Hung et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- PP2A impaired activity is a common event in acute myeloid leukemia and its activation by forskolin has a potent anti-leukemic effect
- (2011) I Cristóbal et al. LEUKEMIA
- Modulation of Protein Phosphatase 2A Activity Alters Androgen-Independent Growth of Prostate Cancer Cells: Therapeutic Implications
- (2011) A. Bhardwaj et al. MOLECULAR CANCER THERAPEUTICS
- Open-label, phase I dose-escalation study of sodium selenate, a novel activator of PP2A, in patients with castration-resistant prostate cancer
- (2010) N M Corcoran et al. BRITISH JOURNAL OF CANCER
- FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cells
- (2010) Francesca Tonelli et al. CELLULAR SIGNALLING
- CIP2A expression is increased in prostate cancer
- (2010) Markku H Vaarala et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Ceramide Produces Apoptosis Through Induction of p27kip1by Protein Phosphatase 2A-dependent Akt Dephosphorylation in PC-3 Prostate Cancer Cells
- (2010) Sang Woo Kim et al. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES
- Multiple pathways regulated by the tumor suppressor PP2A in transformation
- (2008) Jukka Westermarck et al. TRENDS IN MOLECULAR MEDICINE
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