Inhibition by stabilization: targeting the Plasmodium falciparum aldolase–TRAP complex

The apicomplexan glideosome and adhesins – Structures and function

(2015) Lauren E. Boucher et al.   JOURNAL OF STRUCTURAL BIOLOGY

Crystal Structures of Stapled and Hydrogen Bond Surrogate Peptides Targeting a Fully Buried Protein–Helix Interaction

(2014) Christopher H. Douse et al.   ACS Chemical Biology

Targeting a Dynamic Protein-Protein Interaction: Fragment Screening against the Malaria Myosin A Motor Complex

(2014) Christopher H. Douse et al.   ChemMedChem

Plasmodium falciparum aldolase and the C-terminal cytoplasmic domain of certain apical organellar proteins promote actin polymerization

(2014) Suraya A. Diaz et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Pharmacological chaperones stabilize retromer to limit APP processing

(2014) Vincent J Mecozzi et al.   Nature Chemical Biology

Toxoplasmaaldolase is required for metabolism but dispensable for host-cell invasion

(2014) Bang Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identifying novelPlasmodium falciparumerythrocyte invasion receptors using systematic extracellular protein interaction screens

(2013) S. Josefin Bartholdson et al.   CELLULAR MICROBIOLOGY

A thrombospondin structural repeat containing rhoptry protein fromPlasmodium falciparummediates erythrocyte invasion

(2013) Faiza Amber Siddiqui et al.   CELLULAR MICROBIOLOGY

Development of a multifunctional tool for drug screening against plasmodial protein-protein interactions via surface plasmon resonance

(2013) Lauren E. Boucher et al.   JOURNAL OF MOLECULAR RECOGNITION

The compact conformation of the Plasmodium knowlesi myosin tail interacting protein MTIP in complex with the C-terminal helix of myosin A

(2013) Stewart Turley et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

(2013) Frédéric Ariey et al.   NATURE

Small-Molecule Stabilization of Protein-Protein Interactions: An Underestimated Concept in Drug Discovery?

(2012) Philipp Thiel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study

(2012) Aung Pyae Phyo et al.   LANCET

Host cell invasion by apicomplexans: what do we know?

(2012) Daniel Bargieri et al.   TRENDS IN PARASITOLOGY

Shedding of TRAP by a Rhomboid Protease from the Malaria Sporozoite Surface Is Essential for Gliding Motility and Sporozoite Infectivity

(2012) Ijeoma Ejigiri et al.   PLoS Pathogens

Plasmodium sporozoite motility: an update

(2011) Georgina et al.   Frontiers in Bioscience-Landmark

The Phenix software for automated determination of macromolecular structures

(2011) Paul D. Adams et al.   METHODS

Binding ofPlasmodiummerozoite proteins RON2 and AMA1 triggers commitment to invasion

(2011) Prakash Srinivasan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How apicomplexan parasites move in and out of cells

(2010) L David Sibley   CURRENT OPINION IN BIOTECHNOLOGY

Structure-based Design of Novel Small-Molecule Inhibitors of Plasmodium falciparum

(2010) Sandhya Kortagere et al.   Journal of Chemical Information and Modeling

B cell receptor triggering sensitizes human B cells to TRAIL-induced apoptosis

(2010) Andre Ortlieb Guerreiro-Cacais et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Thousands of chemical starting points for antimalarial lead identification

(2010) Francisco-Javier Gamo et al.   NATURE

Chemical genetics of Plasmodium falciparum

(2010) W. Armand Guiguemde et al.   NATURE

Moonlighting enzymes in parasitic protozoa

(2010) PETER W. COLLINGRIDGE et al.   PARASITOLOGY

Intrahost modeling of artemisinin resistance in Plasmodium falciparum

(2010) S. Saralamba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aldolase Is Essential for Energy Production and Bridging Adhesin-Actin Cytoskeletal Interactions during Parasite Invasion of Host Cells

(2009) G. Lucas Starnes et al.   Cell Host & Microbe

The Plasmodium TRAP/MIC2 family member, TRAP-Like Protein (TLP), is involved in tissue traversal by sporozoites

(2008) Cristina K. Moreira et al.   CELLULAR MICROBIOLOGY

Functional Characterization of a RedundantPlasmodiumTRAP Family Invasin, TRAP-Like Protein, by Aldolase Binding and a Genetic Complementation Test

(2008) Kirsten Heiss et al.   EUKARYOTIC CELL

A new method for ligand docking to flexible receptors by dual alanine scanning and refinement (SCARE)

(2008) Giovanni Bottegoni et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Host Cell Egress and Invasion Induce Marked Relocations of Glycolytic Enzymes in Toxoplasma gondii Tachyzoites

(2008) Sebastien Pomel et al.   PLoS Pathogens