4.4 Article

Malaria-like symptoms associated with a natural Plasmodium reichenowi infection in a chimpanzee

Journal

MALARIA JOURNAL
Volume 14, Issue -, Pages -

Publisher

BMC
DOI: 10.1186/s12936-015-0743-y

Keywords

Plasmodium; Pan troglodytes; Chimpanzee; Symptom; Malaria; Anaemia; Hyperthermia; Fever

Funding

  1. CIRMF
  2. CNRS
  3. IRD
  4. Agence Nationale pour la Recherche (ANR JCJC SVSE [7-2012 ORIGIN]

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Although Plasmodium infections have never been clearly associated with symptoms in non-human primates, the question of the pathogenicity of Plasmodium parasites in non-human primates still remains unanswered. A young chimpanzee, followed before and after release to a sanctuary, in a semi-free ranging enclosure located in an equatorial forest, showed fever and strong anaemia associated with a high Plasmodium reichenowi infection, shortly after release. The animal recovered from anaemia after several months despite recurrent infection with other Plasmodium species. This may be the first description of malaria-like symptoms in a chimpanzee infected with Plasmodium.

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