Journal
MACROMOLECULAR RAPID COMMUNICATIONS
Volume 36, Issue 22, Pages 2000-2005Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/marc.201500359
Keywords
block copolymers; drug delivery; microfluidics; nanoparticles; self-assembly
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Funding
- NSERC Canada
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Hierarchical semicrystalline block copolymer nanoparticles are produced in a segmented gas-liquid microfluidic reactor with top-down control of multiscale structural features, including nanoparticle morphologies, sizes, and internal crystallinities. Control of multiscale structure on disparate length scales by a single control variable (flow rate) enables tailoring of drug delivery nanoparticle function including release rates.
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