Enhancement of antibody-dependent cell-mediated cytotoxicity by endowing IgG with FcαRI (CD89) binding

Antibody-Dependent Cell-Mediated Cytotoxicity Effector-Enhanced EphA2 Agonist Monoclonal Antibody Demonstrates Potent Activity against Human Tumors

(2015) Elizabeth M. Bruckheimer et al.   NEOPLASIA

IgGA: A “Cross-Isotype” Engineered Human Fc Antibody Domain that Displays Both IgG-like and IgA-like Effector Functions

(2014) William Kelton et al.   CHEMISTRY & BIOLOGY

Targeting regulatory T cells in tumor immunotherapy

(2014) Mark J Smyth et al.   IMMUNOLOGY AND CELL BIOLOGY

OX40 engagement depletes intratumoral Tregs via activating FcγRs, leading to antitumor efficacy

(2014) Yannick Bulliard et al.   IMMUNOLOGY AND CELL BIOLOGY

Neutrophils mediate antibody-induced antitumor effects in mice

(2013) M. Albanesi et al.   BLOOD

IgAEGFR antibodies mediate tumour killingin vivo

(2013) Peter Boross et al.   EMBO Molecular Medicine

Th1 cytokines are more effective than Th2 cytokines at licensing anti-tumour functions in CD40-activated human macrophages in vitro

(2013) Nadia Luheshi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Effect of a tail piece cysteine deletion on biochemical and functional properties of an epidermal growth factor receptor-directed IgA2 m(1) antibody

(2013) Christina Brunke et al.   mAbs

Effective Phagocytosis of Low Her2 Tumor Cell Lines with Engineered, Aglycosylated IgG Displaying High FcγRIIa Affinity and Selectivity

(2012) Sang Taek Jung et al.   ACS Chemical Biology

Characterization of a Mutated IgA2 Antibody of the m(1) Allotype against the Epidermal Growth Factor Receptor for the Recruitment of Monocytes and Macrophages

(2012) Stefan Lohse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel Human IgA Monoclonal Antibody Protects against Tuberculosis

(2011) S. Balu et al.   JOURNAL OF IMMUNOLOGY

Engineered Fc variant antibodies with enhanced ability to recruit complement and mediate effector functions

(2010) Gregory L. Moore et al.   mAbs

Optimization of Fc-mediated effector functions of monoclonal antibodies

(2009) William R Strohl   CURRENT OPINION IN BIOTECHNOLOGY

Immunoglobulin A: FcαRI Interactions Induce Neutrophil Migration Through Release of Leukotriene B4

(2009) Lydia van der Steen et al.   GASTROENTEROLOGY

Polymorphonuclear neutrophils and cancer: Intense and sustained neutrophilia as a treatment against solid tumors

(2009) Juan Carlos Souto et al.   MEDICINAL RESEARCH REVIEWS

Optimization of antibody binding to Fc RIIa enhances macrophage phagocytosis of tumor cells

(2008) J. O. Richards et al.   MOLECULAR CANCER THERAPEUTICS