Journal
HYPERTENSION RESEARCH
Volume 35, Issue 8, Pages 796-799Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/hr.2012.82
Keywords
antihypertensive drugs; candidate genes; GWAS; pharmacogenomics; tailored medicine
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Funding
- Program for Promotion of Fundamental Studies of National Institute of Biomedical Innovation of Japan [HR:22-2-5]
- Ministry of Education, Culture, Sports, Science and Technology of Japan [KK: 22510211]
- Grants-in-Aid for Scientific Research [21390222] Funding Source: KAKEN
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Pharmacogenomic studies aim to clarify the role of various genes and their variations in relation to the effects of antihypertensive drugs to establish a personalized pharmacotherapeutic treatment based on a patient's genetic background. Until recently, there have been numerous pharmacogenetic/pharmacogenomic studies on antihypertensive drugs using candidate genes, but only a few genome-wide approaches have been completed. In this review article, we discuss current trends and future directions of pharmacogenomic studies on antihypertensive drugs. Hypertension Research (2012) 35, 796-799; doi:10.1038/hr.2012.82; published online 28 June 2012
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