Article
Obstetrics & Gynecology
Jiang-Nan Wu, Ming-Qing Li, Feng Xie, Bin Zhang
Summary: The study found that the second-trimester measured UtA indices had a satisfactory performance at the 9th week in predicting subsequent preeclampsia. The right UtA-RI was the first choice in ruling out preeclampsia, while the left UtA-PI showed the best authenticity of the prediction.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Review
Obstetrics & Gynecology
Ruijuan Zhi, Xiangping Tao, Qingtao Li, Ming Yu, Honge Li
Summary: This systematic review and meta-analysis explored the association between UtA measurements and SGA throughout the whole pregnancy. The findings suggest that abnormal UtA measurements are linked to increased odds of SGA, indicating that UtA could serve as an adjunctive screening method for SGA.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Medicine, General & Internal
Stephen Contag, Silvia Visentin, Katherine Goetzinger, Erich Cosmi
Summary: The study compared the effectiveness of cerebral-placental ratio (CPR) and cerebral-renal ratio (CRR) in predicting adverse neonatal outcomes among growth-restricted fetuses. The results showed that the umbilical artery pulsatility index performed the best in detecting composite adverse neonatal outcomes, with no additional benefit from using CRR compared to CPR. The data did not support the use of renal artery Doppler as a useful clinical test for identifying fetuses at risk for adverse neonatal outcomes.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Multidisciplinary Sciences
Yonggang Zhang, Yipeng Zhang, Limin Zhao, Junzhu Shi, Hongling Yang, Maurizio Mandala
Summary: This study aimed to predict preeclampsia by combining plasma protein SerpinA5 with uterine artery Doppler ultrasound and clinical risk factors during the first trimester. Results showed that SerpinA5 levels were elevated in preeclampsia placental tissue and plasma, potentially interfering with trophoblastic cell invasion. When combined with UtA-PI, pre-pregnancy BMI, and family history of PE, plasma SerpinA5 could effectively predict preeclampsia.
Article
Veterinary Sciences
Elshymaa A. Abdelnaby, Ibrahim A. Emam, Hossam R. El-Sherbiny, Aya M. Fadl
Summary: This study aimed to investigate the correlation between the pulsed wave spectral indices of the middle uterine artery and placental development in pregnant jennies during mid-late pregnancies, and establish umbilical Doppler values for different ages and gestational months. The results showed significant changes in the blood flow indices of the uterus and umbilical arteries during pregnancy.
BMC VETERINARY RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Elahe Mesdaghinia, Farah Shahin, Amir Ghaderi, Daryoush Shahin, Mohammad Shariat, Hamidreza Banafshe
Summary: This study evaluated the effects of selenium supplementation on clinical outcomes, metabolic profiles, and uterine artery pulsatility index (PI) in high-risk mothers in terms of preeclampsia (PE) screening with quad marker. The results showed that selenium supplementation had beneficial effects on serum selenium levels, antioxidant capacity, inflammatory markers, uterine artery PI, and mental health.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Article
Multidisciplinary Sciences
Piengbulan Yapan, Suphaphon Tachawatcharapunya, Supitchaya Surasereewong, Piyatida Thongkloung, Julaporn Pooliam, Liona C. Poon, Tuangsit Wataganara
Summary: This study aimed to investigate the impact of a history of previous Cesarean delivery (CD) on uterine artery (UtA) Doppler indices throughout pregnancy. The results showed no difference in the measurements and temporal changes of UtA Doppler indices between women with and without CD. The study found that the Delta values of UtA Doppler indices exhibited a biphasic pattern, decreasing until the second trimester and then increasing.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, General & Internal
Xianjing Xie, Dan Chen, Xingyu Yang, Yunyun Cao, Yuna Guo, Weiwei Cheng
Summary: This study aimed to determine whether the combination of pregnancy-associated endothelial cell-specific molecule 1 (ESM-1), the placental growth factor (PLGF) in the first- and second-trimester maternal serum, and the uterine artery Doppler pulsatility index (PI) in the second trimester can predict preeclampsia (PE). The results showed that levels of ESM-1 and PLGF, as well as PI, were associated with PE. The combination of these biomarkers improved the screening efficiency of PE prediction, especially for severe preeclampsia (SPE).
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Toxicology
Marcus Garcia, Raul Salazar, Thomas Wilson, Selita Lucas, Guy Herbert, Tamara Young, Jessica Begay, Jesse L. Denson, Katherine Zychowski, Ryan Ashley, Stephanie Byrum, Samuel Mackintosh, Barry E. Bleske, Andrew K. Ottens, Matthew J. Campen
Summary: Exposure to ozone during early placental formation in pregnancy can lead to more adverse cardiovascular effects in rats at term, with changes consistent with markers of preeclampsia. Additionally, exposure to 0.3 ppm ozone at GD10 induced late-stage cardiovascular outcomes in dams that were not seen in GD20-exposed dams.
TOXICOLOGICAL SCIENCES
(2021)
Article
Multidisciplinary Sciences
Jezid Miranda, Cristina Paules, Guillaume Noell, Lina Youssef, Angel Paternina-Caicedo, Francesca Crovetto, Nicolau Canellas, Maria L. Garcia-Martin, Nuria Amigo, Elisenda Eixarch, Rosa Faner, Francesc Figueras, Rui Simos, Fatima Crispi, Eduard Gratacos
Summary: This study used machine learning to conduct cluster analysis of FGR, confirming the existence of two distinct subtypes with different molecular and clinical features. The clusters generated by machine learning outperformed single data subtype analysis in predicting adverse maternal and neonatal outcomes, supporting the current clinical classification.
Article
Endocrinology & Metabolism
Leah Paranavitana, Melissa Walker, Anjana Ravi Chandran, Natasha Milligan, Shiri Shinar, Clare L. Whitehead, Sebastian R. Hobson, Lena Serghides, W. Tony Parks, Ahmet A. Baschat, Christopher K. Macgowan, John G. Sled, John C. Kingdom, Lindsay S. Cahill
Summary: The study found that there is no difference in uterine artery pulsatility index (PI) between female and male fetuses in normal pregnancies, but in complicated pregnancies (preeclampsia, preterm birth, or fetal growth restriction), the trajectory of PI varies by fetal sex, with male fetuses showing a more progressive deterioration in uteroplacental perfusion over gestation. This highlights the importance of considering fetal sex when interpreting hemodynamic markers of placental maturation, as observed through changes in uterine artery PI.
BIOLOGY OF SEX DIFFERENCES
(2021)
Article
Medicine, General & Internal
Anne Karge, Silvia M. Lobmaier, Bernhard Haller, Bettina Kuschel, Javier U. Ortiz
Summary: This study evaluated the association between CPR and mUtA-PI with adverse perinatal outcomes in VSGA and SGA fetuses, finding that CPR had predictive value for adverse perinatal outcomes in SGA, while VSGA fetuses were more frequently affected by adverse perinatal outcomes regardless of Doppler values.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Obstetrics & Gynecology
Ersin Cintesun, Feyza Nur Incesu Cintesun, Nigar Mammadova, Cetin Celik
Summary: This study aimed to investigate the influence of progesterone on the uterine artery Doppler pulsatility index and found that there was no significant impact. The results showed no significant differences in PI values between patients using progesterone and those who were not using progesterone at 11-14 gestational weeks. Further prospective studies are needed to consider potential confounding factors, including serum progesterone levels.
GINEKOLOGIA POLSKA
(2021)
Article
Obstetrics & Gynecology
Droima Stevens, Veronique Schiffer, Carmen Severens-Rijvers, Johnny de Nobrega Teixeira, Ashlee van Haren, Marc Spaanderman, Salwan Al-Nasiry
Summary: The study revealed that histologic decidual vasculopathy is associated with abnormal uterine artery Doppler, independent of clinical phenotype during pregnancy.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2022)
Article
Medicine, General & Internal
Christine Ladd-Acosta, Elizabeth Vang, Emily S. Barrett, Catherine M. Bulka, Nicole R. Bush, Andres Cardenas, Dana Dabelea, Anne L. Dunlop, Rebecca C. Fry, Xingyu Gao, Jaclyn M. Goodrich, Julie Herbstman, Marie-France Hivert, Linda G. Kahn, Margaret R. Karagas, Elizabeth M. Kennedy, Anna K. Knight, Sahra Mohazzab-Hosseinian, Andreanne Morin, Zhongzheng Niu, T. Michael O'Shea, Meredith Palmore, Douglas Ruden, Rebecca J. Schmidt, Alicia K. Smith, Ashley Song, Eliot R. Spindel, Leonardo Trasande, Heather Volk, Daniel J. Weisenberger, Carrie V. Breton
Summary: This US cohort study found that preeclampsia and gestational diabetes delay biological maturity in children, especially in female offspring.
Article
Obstetrics & Gynecology
Lunthaporn Puttanavijarn, Vorapong Phupong
JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2017)
Article
Peripheral Vascular Disease
Adisorn Aksornphusitaphong, Vorapong Phupong
HYPERTENSION RESEARCH
(2018)
Article
Obstetrics & Gynecology
Monchai Santipap, Vorapong Phupong
JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2018)
Article
Multidisciplinary Sciences
Wasinee Tianthong, Vorapong Phupong
SCIENTIFIC REPORTS
(2018)
Article
Obstetrics & Gynecology
Adjima Soongsatitanon, Vorapong Phupong
JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2019)
Article
Obstetrics & Gynecology
Vorapong Phupong, Wilasinee Areeruk, Patau Tantbirojn, Ruangsak Lertkhachonsuk
HYPERTENSION IN PREGNANCY
(2020)
Article
Obstetrics & Gynecology
Thanisa Kitjaras, Vorapong Phupong
Summary: This study compared the levels of SHARP1 in preeclamptic women and normal pregnant women, and found that preeclamptic patients had higher levels of SHARP1. Additionally, preeclamptic women had higher rates of cesarean section, lower neonatal birth weight, and higher rates of neonatal complications compared to normal pregnant women.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Obstetrics & Gynecology
Adjima Soongsatitanon, Vorapong Phupong
Summary: This study demonstrated that the combination of serum PP13 level and uterine artery Doppler in the first trimester increased the sensitivity for predicting preeclampsia.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Siraphat Fungtammasan, Vorapong Phupong
Summary: The study aims to evaluate the efficacy of Moringa oleifera leaves in increasing breastmilk volume in early postpartum mothers through a randomized double-blind trial. The outcomes will provide data on the use of Moringa oleifera as an herbal medication for enhancing breastmilk volume, with the goal of promoting exclusive breastfeeding for the first 6 months as recommended by the World Health Organization.
Article
Multidisciplinary Sciences
Nipp Chantanahom, Vorapong Phupong
Summary: This study identified nulliparity and chronic hypertension as clinical risk factors for developing preeclampsia in twin pregnancies, while low gestational weight gain was found to be a significant protective factor against preeclampsia. These risk factors are important for identifying twin pregnant women at risk and implementing primary prevention measures.
Article
Education, Scientific Disciplines
Ananya Trongpisutsak, Vorapong Phupong
Summary: This study demonstrated that a combination of serum micro RNA-210 and uterine artery Doppler is effective in predicting preeclampsia in the second trimester.
Article
Public, Environmental & Occupational Health
Ratanawadee Sirisangwon, Vorapong Phupong
Summary: Vaginal progesterone supplementation is effective in prolonging the latency period in preterm labor and increasing gestational age at delivery. It also reduces rates of preterm birth, low birth weight, neonatal respiratory distress syndrome, and neonatal intensive care unit admission.
MATERNAL AND CHILD HEALTH JOURNAL
(2021)
Article
Medicine, General & Internal
Vorapong Phupong, Suchada Erjongmanee, Patau Tanbirojn, Ruangsak Lertkhachonsuk
Summary: Partial trisomy 22 is a rare condition that is often associated with structural abnormalities, which can be confirmed through prenatal genetic diagnosis. It is recommended that pregnant women with fetal anomalies undergo prenatal genetic testing to determine the presence of partial trisomy 22 or other rare chromosomal abnormalities.
SAGE OPEN MEDICAL CASE REPORTS
(2021)
Article
Obstetrics & Gynecology
Ruangsak Lertkhachonsuk, Arb-aroon Lertkhachonsuk, Vorapong Phupong
JOURNAL OF REPRODUCTIVE MEDICINE
(2019)
Article
Nutrition & Dietetics
Nalina Bhupornvivat, Vorapong Phupong
ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION
(2017)
