4.1 Article

Does Uric Acid Provide Information About Maternal Condition and Fetal Outcome in Pregnant Women with Hypertension?

Journal

HYPERTENSION IN PREGNANCY
Volume 27, Issue 4, Pages 413-420

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/10641950801955709

Keywords

Hyperuricemia; Pregnancy induced hypertension; Proteinuria; Preeclampsia; Prematurity

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Objective: To evaluate associations between maternal serum uric acid (UA) levels, maternal status, and fetal outcome. Methods: Maternal UA, urinary protein-creatinine ratio (P/C), blood pressure (BP), gestational age at delivery, and birth weight were evaluated in hypertensive pregnant women (n = 58). These were divided into two groups: high UA (357 mol/L) or normal UA (357 mol/L). Results: Maternal diastolic BP and P/C ratio were higher in pregnant women with elevated UA levels. Systolic BP, gestational age and birth weight were not significantly different. Conclusion. UA equal or above 357 mol/L in pregnant hypertensive women was associated with proteinuria and diastolic BP, but not with fetal outcome.

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