Article
Multidisciplinary Sciences
Michael F. La Fountaine, Asante N. Hohn, Caroline L. Leahy, Anthony J. Testa, Joseph P. Weir
Summary: This study found that after 48 hours of concussion, patients had significantly lower Mayer wave activity compared to controls, which returned to normal levels by 1 week post-injury. Additionally, early after concussion, attenuated sympathetic vasomotor tone was present as the main manifestation of autonomic dysfunction.
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
(2022)
Article
Peripheral Vascular Disease
Hiroyuki Kinoshita, Keita Saku, Jumpei Mano, Hiroshi Mannoji, Shigehiko Kanaya, Kenji Sunagawa
Summary: Resting very short-term blood pressure variability is correlated with nocturnal blood pressure variability, and may serve as a predictor for nocturnal blood pressure variability.
HYPERTENSION RESEARCH
(2022)
Article
Peripheral Vascular Disease
Hiroyuki Kinoshita, Keita Saku, Jumpei Mano, Hiroshi Mannoji, Shigehiko Kanaya, Kenji Sunagawa
Summary: This study suggests that very short-term blood pressure variability at rest may predict nocturnal blood pressure variability. This finding has the potential to develop a novel index of blood pressure variability.
HYPERTENSION RESEARCH
(2022)
Article
Peripheral Vascular Disease
Ailsa F. Ralph, Celine Grenier, Hannah M. Costello, Kevin Stewart, Jessica R. Ivy, Neeraj Dhaun, Matthew A. Bailey
Summary: High salt intake leads to hypertension, affecting renal and vascular function in C57BL6/J mice, with a rapid increase in blood pressure observed in male mice within 4 days of dietary switch. The high-salt diet also increases renal artery sensitivity and urinary excretion of adrenaline in these mice.
Review
Neurosciences
Jeann L. Sabino-Carvalho, Barbara Falquetto, Ana C. Takakura, Lauro C. Vianna
Summary: The incidence of Parkinson's disease is increasing worldwide, with nonmotor dysfunctions gaining recognition. Research suggests that baroreflex dysfunction may be an underlying mechanism of cardiovascular dysregulation in PD patients. This review summarizes potential altered central and peripheral mechanisms affecting the feedback-controlled loops in PD patients.
JOURNAL OF NEUROPHYSIOLOGY
(2021)
Article
Peripheral Vascular Disease
Yusuke Sata, Sandra L. Burke, Nina Eikelis, Anna M. D. Watson, Cindy Gueguen, Kristy L. Jackson, Gavin W. Lambert, Kyungjoon Lim, Kate M. Denton, Markus P. Schlaich, Geoffrey A. Head
Summary: Renal denervation, whether total or afferent, can effectively reduce hypertension and sympathetic activity in chronic kidney disease (CKD) rabbits, suggesting that renal afferents play a significant role in driving elevated blood pressure in this model.
Article
Geriatrics & Gerontology
Melanie Dani, Patricia Taraborrelli, Dimitrios Panagopoulos, Andreas Dirksen, Miriam Torocastro, Richard Sutton, Phang Boon Lim
Summary: This article discusses the baroreflex mechanism in blood pressure regulation in older people, as well as the physiological and pathological reasons for its impairment. Additionally, it explores the causes of orthostatic hypotension and supine hypertension in older individuals, along with strategies for managing these conditions.
Review
Peripheral Vascular Disease
Baojian Xue, Alan Kim Johnson
Summary: Hypertension affects over 1 billion individuals worldwide, and the cause is largely unknown. Increased sympathetic nervous system activity is common in hypertensive patients, but the root cause is still unclear. Recent research has found that the neural network controlling sympathetic drive becomes more reactive after exposure to mild challenges, leading to a sensitized hypertensive response. Plasticity in the neural network and the involvement of various factors are necessary for the induction and maintenance of this state. This review discusses the induction and expression of this sensitized hypertensive response in adult animals and the offspring of mothers with prenatal obesity/overnutrition or maternal gestational hypertension, as well as interventions to reverse the effects of stressor-induced sensitization.
Article
Multidisciplinary Sciences
Tianfei Hou, Wen Su, Marilyn J. Duncan, Vsevolozhskaya A. Olga, Zhenheng Guo, Ming C. Gong
Summary: The study reveals that restricting the timing of food intake can prevent nondipping blood pressure in diabetic mice and effectively restore disrupted blood pressure circadian rhythm.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Peripheral Vascular Disease
Mark B. Badrov, Jeung-Ki Yoo, Sarah L. Hissen, David B. Nelson, J. Kevin Shoemaker, Qi Fu
Summary: This study tested whether women who develop gestational hypertension (GH) display abnormal sympathetic action potential (AP) discharge patterns in late pregnancy (32-36 weeks), both at rest and during postural stress. The results showed that the burst frequency of muscle sympathetic nerve activity was elevated in GH compared to the control groups. Moreover, the content per integrated burst and the total AP firing frequency were also higher in the GH group. In conclusion, women who develop GH exhibit aberrant sympathetic AP firing patterns in both supine and upright postures.
Article
Peripheral Vascular Disease
Sean D. Stocker, Megan M. Wenner, William B. Farquhar, Kirsteen N. Browning
Summary: This study found that activation of OVLT neurons leads to hypertension through sympathetic nerve activation.
Article
Peripheral Vascular Disease
Guido Grassi, Fosca Quarti-Trevano, Gino Seravalle, Raffaella Dell'Oro, Jennifer Vanoli, Gianluca Perseghin, Giuseppe Mancia
Summary: The study investigated the differences in blood pressure values when measured with or without a doctor present. The results showed that there were significant increases in blood pressure and sympathetic nerve traffic when BP was measured in the presence of a doctor, while there were modest decreases in these values during unattended BP measurement. This suggests that the presence of a doctor during BP measurement may affect cardiovascular and neural responses.
Article
Sport Sciences
R. A. C. H. E. L. J. SKOW, G. R. A. H. A. M. M. FRASER, C. R. A. I. G. D. STEINBACK, M. A. R. G. I. E. H. DAVENPORT
Summary: This study investigated the impact of aerobic exercise during pregnancy on the sympathetic regulation of blood pressure. The results showed that exercise attenuated the rise in MSNA and the blunting of neurovascular transduction, which may partially explain the lower risk of developing gestational hypertension in active pregnant women.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2021)
Article
Nutrition & Dietetics
Tianfei Hou, Aaron N. Chacon, Wen Su, Yuriko Katsumata, Zhenheng Guo, Ming C. Gong
Summary: Disruption of blood pressure circadian rhythm is associated with an increased risk of cardiovascular events. Changing food availability time alters blood pressure rhythm in mice. Light-phase time-restricted feeding can result in reverse dipping of blood pressure, and this effect may be mediated by the sympathetic nervous system.
FRONTIERS IN NUTRITION
(2022)
Article
Endocrinology & Metabolism
Neil J. McMillan, Rogerio N. Soares, Jennifer L. Harper, Brian Shariffi, Alfonso Moreno-Cabanas, Timothy B. Curry, Camila Manrique-Acevedo, Jaume Padilla, Jacqueline K. Limberg
Summary: This study examines whether peripheral vasodilation induced by insulin contributes to increased muscle sympathetic nerve activity (MSNA) via arterial baroreflex-mediated mechanisms. The results show that insulin-induced peripheral vasodilation plays a role in the increase of MSNA during hyperinsulinemia.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
(2022)
