The immunosuppressive ligands PD-L1 and CD200 are linked in AML T-cell immunosuppression: identification of a new immunotherapeutic synapse

Blockade of CD200 in the Presence or Absence of Antibody Effector Function: Implications for Anti-CD200 Therapy

(2014) A. Kretz-Rommel et al.   JOURNAL OF IMMUNOLOGY

The stimulation of PD-L1-specific cytotoxic T lymphocytes can both directly and indirectly enhance antileukemic immunity

(2014) S M Ahmad et al.   Blood Cancer Journal

PD-L1 expression and tumor-infiltrating lymphocytes

(2014) Kurt A Schalper   OncoImmunology

Survival and cure of acute myeloid leukaemia in England, 1971-2006: a population-based study

(2013) Anjali Shah et al.   BRITISH JOURNAL OF HAEMATOLOGY

Dual Blockade of PD-1 and CTLA-4 Combined with Tumor Vaccine Effectively Restores T-Cell Rejection Function in Tumors

(2013) J. Duraiswamy et al.   CANCER RESEARCH

IL-21 promotes the expansion of CD27+CD28+ tumor infiltrating lymphocytes with high cytotoxic potential and low collateral expansion of regulatory T cells

(2013) Saskia JAM Santegoets et al.   Journal of Translational Medicine

Coinhibitory molecules in hematologic malignancies: targets for therapeutic intervention

(2012) W. J. Norde et al.   BLOOD

Expression of CD200 on AML blasts directly suppresses memory T-cell function

(2012) S J Coles et al.   LEUKEMIA

Increased CD200 expression in acute myeloid leukemia is linked with an increased frequency of FoxP3+ regulatory T cells

(2012) S J Coles et al.   LEUKEMIA

Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia

(2011) Q. Zhou et al.   BLOOD

CD200 expression suppresses natural killer cell function and directly inhibits patient anti-tumor response in acute myeloid leukemia

(2011) S J Coles et al.   LEUKEMIA

In acute myeloid leukemia, B7-H1 (PD-L1) protection of blasts from cytotoxic T cells is induced by TLR ligands and interferon-gamma and can be reversed using MEK inhibitors

(2010) Céline Berthon et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Functional Unresponsiveness and Replicative Senescence of Myeloid Leukemia Antigen-specific CD8+ T Cells After Allogeneic Stem Cell Transplantation

(2009) G. L. Beatty et al.   CLINICAL CANCER RESEARCH