AML1/ETO cooperates with HIF1α to promote leukemogenesis through DNMT3a transactivation

A nucleolin-DNMT1 regulatory axis in acute myeloid leukemogenesis

(2015) Na Shen et al.   Oncotarget

IFN-  Induces Transcription of Hypoxia-Inducible Factor-1  to Inhibit Proliferation of Human Endothelial Cells

(2014) S. A. Gerber et al.   JOURNAL OF IMMUNOLOGY

Epigenetic silencing of microRNA-193a contributes to leukemogenesis in t(8;21) acute myeloid leukemia by activating the PTEN/PI3K signal pathway

(2012) Y. Li et al.   BLOOD

PRMT1 interacts with AML1-ETO to promote its transcriptional activation and progenitor cell proliferative potential

(2012) W.-J. Shia et al.   BLOOD

Chromatin modifications induced by the AML1-ETO fusion protein reversibly silence its genomic targets through AML1 and Sp1 binding motifs

(2012) A Maiques-Diaz et al.   LEUKEMIA

Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding

(2012) A Ptasinska et al.   LEUKEMIA

Elevated HIF-1α expression of acute myelogenous leukemia stem cells in the endosteal hypoxic zone may be a cause of minimal residual disease in bone marrow after chemotherapy

(2012) T. Matsunaga et al.   LEUKEMIA RESEARCH

Multilevel regulation of HIF-1 signaling by TTP

(2012) Michael Fähling et al.   MOLECULAR BIOLOGY OF THE CELL

Hypoxia-induced DNA hypermethylation in human pulmonary fibroblasts is associated with Thy-1 promoter methylation and the development of a pro-fibrotic phenotype

(2012) Claire M Robinson et al.   RESPIRATORY RESEARCH

Targeting HIF1α Eliminates Cancer Stem Cells in Hematological Malignancies

(2011) Yin Wang et al.   Cell Stem Cell

Functional regulation of HIF-1α under normoxia-is there more than post-translational regulation?

(2011) A. Kuschel et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Hypoxia Induces Genomic DNA Demethylation through the Activation of HIF-1  and Transcriptional Upregulation of MAT2A in Hepatoma Cells

(2011) Q. Liu et al.   MOLECULAR CANCER THERAPEUTICS

Hypoxia-induced methylation of a pontin chromatin remodeling factor

(2011) J. S. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Leukemogenicity of AML1-ETO Is Dependent on Site-Specific Lysine Acetylation

(2011) L. Wang et al.   SCIENCE

HIF1A Overexpression Is Associated with Poor Prognosis in a Cohort of 731 Colorectal Cancers

(2010) Yoshifumi Baba et al.   AMERICAN JOURNAL OF PATHOLOGY

High VEGFC expression is associated with unique gene expression profiles and predicts adverse prognosis in pediatric and adult acute myeloid leukemia

(2010) H. J. M. de Jonge et al.   BLOOD

Sp1/NFκB/HDAC/miR-29b Regulatory Network in KIT-Driven Myeloid Leukemia

(2010) Shujun Liu et al.   CANCER CELL

DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid Leukemia

(2010) Maria E. Figueroa et al.   CANCER CELL

Genome-wide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction

(2010) Amaya Ortiz-Barahona et al.   NUCLEIC ACIDS RESEARCH

Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts

(2009) David R. Mole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis

(2009) X. Xia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AML1/ETO Oncoprotein Is Directed to AML1 Binding Regions and Co-Localizes with AML1 and HEB on Its Targets

(2008) Alessandro Gardini et al.   PLoS Genetics