Aetiology of hypospadias: a systematic review of genes and environment

Parental occupational exposure to endocrine disrupting chemicals and male genital malformations: A study in the danish national birth cohort study

(2011) María M Morales-Suárez-Varela et al.   Environmental Health

Human balanced translocation and mouse gene inactivation implicate Basonuclin 2 in distal urethral development

(2011) Elizabeth J Bhoj et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Immunohistochemical Characterization of Sonic Hedgehog and its Downstream Signaling Molecules During Human Penile Development

(2011) Bahig M. Shehata et al.   Fetal and Pediatric Pathology

Polymorphism in CYP1A1, GSTMI,GSTT1 genes and organochlorine pesticides in the etiology of hypospadias

(2011) Chandra ShekharYadav et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Evidence for Epigenetic Abnormalities of the Androgen Receptor Gene in Foreskin from Children with Hypospadias

(2011) A. Vottero et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Hypospadias associated with hypertelorism, the mildest phenotype of Opitz syndrome

(2011) Xufeng Zhang et al.   JOURNAL OF HUMAN GENETICS

Water Consumption and Use, Trihalomethane Exposure, and the Risk of Hypospadias

(2011) N. Iszatt et al.   PEDIATRICS

Hypospadias in Istanbul: Incidence and risk factors

(2011) Yasemin Akin et al.   PEDIATRICS INTERNATIONAL

13q33.2 deletion: a rare cause of ambiguous genitalia in a male newborn with growth restriction

(2010) JH Andresen et al.   ACTA PAEDIATRICA

Secular trends of hypospadias prevalence and factors associated with it in southeast China during 1993-2005

(2010) Lei Jin et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Hypospadias and halogenated organic pollutant levels in maternal mid-pregnancy serum samples

(2010) Suzan L Carmichael et al.   CHEMOSPHERE

Efficacy of medical care of epileptic pregnant women based on the rate of congenital abnormalities in their offspring

(2010) Ferenc Bánhidy et al.   CONGENITAL ANOMALIES

Male reproductive tract abnormalities: More common after assisted reproduction?

(2010) Simone Funke et al.   EARLY HUMAN DEVELOPMENT

Mutational study of the MAMLD1-gene in hypospadias

(2010) Yougen Chen et al.   European Journal of Medical Genetics

Teratogenic mechanisms of medical drugs

(2010) M. M. H. J. van Gelder et al.   HUMAN REPRODUCTION UPDATE

Testicular dysgenesis syndrome comprises some but not all cases of hypospadias and impaired spermatogenesis

(2010) N. Jørgensen et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Maternal body mass index and congenital anomaly risk: a cohort study

(2010) J Rankin et al.   INTERNATIONAL JOURNAL OF OBESITY

Genetics of Hypospadias: Are Single-Nucleotide Polymorphisms inSRD5A2,ESR1,ESR2, andATF3Really Associated with the Malformation?

(2010) Loes F. M. van der Zanden et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

What is new in cryptorchidism and hypospadias—a critical review on the testicular dysgenesis hypothesis

(2010) Jorgen Thorup et al.   JOURNAL OF PEDIATRIC SURGERY

Genetic Polymorphisms of 17β-Hydroxysteroid Dehydrogenase 3 and the Risk of Hypospadias

(2010) Fumihiro Sata et al.   Journal of Sexual Medicine

Common variants in DGKK are strongly associated with risk of hypospadias

(2010) Loes F M van der Zanden et al.   NATURE GENETICS

Valproic Acid Monotherapy in Pregnancy and Major Congenital Malformations

(2010) Janneke Jentink et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of De Novo Copy Number Variants Associated with Human Disorders of Sexual Development

(2010) Mounia Tannour-Louet et al.   PLoS One

Delivery outcome after maternal use of antidepressant drugs in pregnancy: an update using Swedish data

(2010) M. Reis et al.   PSYCHOLOGICAL MEDICINE

Hypospadias in males with intrauterine growth restriction due to placental insufficiency: The placental role in the embryogenesis of male external genitalia

(2009) Yoav Yinon et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Mowat-Wilson syndrome: Facial phenotype changing with age: Study of 19 Italian patients and review of the literature

(2009) L. Garavelli et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Maternal thyroid disease, thyroid medication use, and selected birth defects in the National Birth Defects Prevention Study

(2009) Marilyn L. Browne et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Hypospadias: risk factor patterns and different phenotypes

(2009) Marijn M. Brouwers et al.   BJU INTERNATIONAL

Risk of Hypospadias in Newborn Infants Exposed to Valproic Acid During the First Trimester of Pregnancy

(2009) Elvira Rodríguez-Pinilla et al.   DRUG SAFETY

Steroidogenesis in the Fetal Testis and Its Susceptibility to Disruption by Exogenous Compounds

(2009) Hayley M. Scott et al.   ENDOCRINE REVIEWS

Maternal Pregnancy Levels of Polychlorinated Biphenyls and Risk of Hypospadias and Cryptorchidism in Male Offspring

(2009) Katherine A. McGlynn et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Loratadine During Pregnancy and Hypospadias

(2009) Lars Pedersen et al.   EPIDEMIOLOGY

Familial Coaggregation of Cryptorchidism and Hypospadias

(2009) Tine H. Schnack et al.   EPIDEMIOLOGY

The spectrum of phenotypes associated with mutations in steroidogenic factor 1 (SF-1, NR5A1, Ad4BP) includes severe penoscrotal hypospadias in 46,XY males without adrenal insufficiency

(2009) Birgit Köhler et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Prevalence of Hypospadias in Danish Boys: A Longitudinal Study, 1977–2005

(2009) Lars Lund et al.   EUROPEAN UROLOGY

Does a testicular dysgenesis syndrome exist?

(2009) O. Akre et al.   HUMAN REPRODUCTION

Maternal Corticosteroid Use and Hypospadias

(2009) Suzan L. Carmichael et al.   JOURNAL OF PEDIATRICS

Familial Coaggregation of Cryptorchidism, Hypospadias, and Testicular Germ Cell Cancer: A Nationwide Cohort Study

(2009) Tine H. Schnack et al.   JNCI-Journal of the National Cancer Institute

Hypospadias Rates in New York State are Not Increasing

(2009) Harry Fisch et al.   JOURNAL OF UROLOGY

Genetic Interactions of the Androgen and Wnt/β-Catenin Pathways for the Masculinization of External Genitalia

(2009) Shinichi Miyagawa et al.   MOLECULAR ENDOCRINOLOGY

Implications of epigenetics and genomic imprinting in assisted reproductive technologies

(2009) Shari L. Laprise   MOLECULAR REPRODUCTION AND DEVELOPMENT

Parental occupational exposure to potential endocrine disrupting chemicals and risk of hypospadias in infants

(2009) N. Nassar et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Use of biocides and insect repellents and risk of hypospadias

(2009) J Dugas et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Increasing Prevalence of Hypospadias Associated With Various Perinatal Risk Factors in Chinese Newborns

(2009) Ge Sun et al.   UROLOGY

Maternal Use of Oral Contraceptives During Early Pregnancy and Risk of Hypospadias in Male Offspring

(2009) Mette Nørgaard et al.   UROLOGY

Maternal and fetal risk factors associated with severity of hypospadias: A comparison of mild and severe cases

(2009) William H. Carlson et al.   Journal of Pediatric Urology

Maternal use of loperamide in early pregnancy and delivery outcome

(2008) Bengt Källén et al.   ACTA PAEDIATRICA

Chromosome deletions in 13q33–34: Report of four patients and review of the literature

(2008) Joanna Walczak-Sztulpa et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Antifungal drugs and the risk of selected birth defects

(2008) Tonia C. Carter et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Tissue-specific requirements of  -catenin in external genitalia development

(2008) C. Lin et al.   DEVELOPMENT

Maternal and Gestational Risk Factors for Hypospadias

(2008) Olof Akre et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Endocrine Disruptors in the Workplace, Hair Spray, Folate Supplementation, and Risk of Hypospadias: Case–Control Study

(2008) Gillian Ormond et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Activating transcription factor 3: a hormone responsive gene in the etiology of hypospadias

(2008) Ana Beleza-Meireles et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Mutations of CXorf6 are associated with a range of severities of hypospadias

(2008) Nicolas Kalfa et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects

(2008) Richard M. Sharpe et al.   FERTILITY AND STERILITY

A new susceptibility locus for hypospadias on chromosome 7q32.2-q36.1

(2008) Hanh T. T. Thai et al.   HUMAN GENETICS

Genetic polymorphisms of ESR1 and ESR2 that may influence estrogen activity and the risk of hypospadias

(2008) S. Ban et al.   HUMAN REPRODUCTION

17- -Estradiol in relation to age at menarche and adult obesity in premenopausal women

(2008) A. Emaus et al.   HUMAN REPRODUCTION

A Novel Homozygous Mutation inCYP11A1Gene Is Associated with Late-Onset Adrenal Insufficiency and Hypospadias in a 46,XY Patient

(2008) Petr Rubtsov et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Placental insufficiency in early gestation is associated with hypospadias

(2008) Takao Fujimoto et al.   JOURNAL OF PEDIATRIC SURGERY

Genomic Variants of ATF3 in Patients With Hypospadias

(2008) Nicolas Kalfa et al.   JOURNAL OF UROLOGY

Hypospadias and Intake of Nutrients Related to One-Carbon Metabolism

(2008) Suzan L. Carmichael et al.   JOURNAL OF UROLOGY

Topiramate in pregnancy: Preliminary experience from the UK Epilepsy and Pregnancy Register

(2008) S. Hunt et al.   NEUROLOGY

Maternal diet and the risk of hypospadias and cryptorchidism in the offspring

(2008) Felice Giordano et al.   PAEDIATRIC AND PERINATAL EPIDEMIOLOGY

Parental age as a risk factor for isolated congenital malformations in a Polish population

(2008) Anna Materna-Kiryluk et al.   PAEDIATRIC AND PERINATAL EPIDEMIOLOGY

Maternal hypertension, antihypertensive medication use, and the risk of severe hypospadias

(2007) Alissa R. Caton et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Testicular Dysgenesis Syndrome and the Estrogen Hypothesis: A Quantitative Meta-Analysis

(2007) Olwenn V. Martin et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Maternal exposure to water disinfection by-products during gestation and risk of hypospadias

(2007) T J Luben et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE