Gene dosage reductions of Trf1 and/or Tin2 induce telomere DNA damage and lymphoma formation in aging mice

LMP1 mediates multinuclearity through downregulation of shelterin proteins and formation of telomeric aggregates

(2015) V. Lajoie et al.   BLOOD

POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia

(2013) Andrew J Ramsay et al.   NATURE GENETICS

Telomere dysfunction and activation of alternative lengthening of telomeres in B-lymphocytes infected by Epstein–Barr virus

(2013) S A Kamranvar et al.   ONCOGENE

Conditional TRF1 knockout in the hematopoietic compartment leads to bone marrow failure and recapitulates clinical features of dyskeratosis congenita

(2012) F. Beier et al.   BLOOD

Mutations in the telomere capping complex in bone marrow failure and related syndromes

(2012) A. J. Walne et al.   HAEMATOLOGICA

Dyskeratosis Congenita

(2011) I. Dokal   Hematology-American Society of Hematology Education Program

Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice

(2009) P. Martinez et al.   GENES & DEVELOPMENT

Chromosomal rearrangements after ex vivo Epstein–Barr virus (EBV) infection of human B cells

(2009) S Lacoste et al.   ONCOGENE

How Shelterin Protects Mammalian Telomeres

(2008) Wilhelm Palm et al.   Annual Review of Genetics

The 3D nuclear organization of telomeres marks the transition from Hodgkin to Reed–Sternberg cells

(2008) H Knecht et al.   LEUKEMIA