Journal
HUMAN REPRODUCTION
Volume 26, Issue 8, Pages 1941-1944Publisher
OXFORD UNIV PRESS
DOI: 10.1093/humrep/der150
Keywords
ovarian reserve; counselling; assisted reproduction; dehydroepiandrosterone
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Dehydroepiandrosterone (DHEA) is being presented as a miracle-drug for the treatment of women responding poorly to gonadotrophin stimulation, while the debate on its actual effectiveness is still ongoing. We would like to present how insufficient the current evidence of acceptable quality is to warrant a conclusion that DHEA supplementation is an effective treatment for women with diminished ovarian reserve. We believe that large-scale, well-designed confirmatory studies are necessary to prove the efficacy of DHEA before it can be recommended for routine use.
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