Journal
LETTERS IN ORGANIC CHEMISTRY
Volume 12, Issue 7, Pages 465-470Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1570178612666150331204620
Keywords
Fe3O4 nanoparticles; 3,4-substituted coumarins; solvent-free; one-pot
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Funding
- Young Researchers Club (Islamic Azad University, Iran), Iran
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A clean, efficient and facile one-pot protocol was developed for the synthesis of a series of new 3,4-substituted coumarins (warfarin analogous compounds) by a one-pot reaction using catalytic amount of Fe3O4 nanoparticles under solvent-free conditions. This green method offers significant advantages in terms of its simplicity, low catalyst loadings, high product yields, recyclability of catalyst and non-toxic nature.
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