Review
Medicine, General & Internal
Martina Balli, Anna Cecchele, Valerio Pisaturo, Sofia Makieva, Giorgia Carullo, Edgardo Somigliana, Alessio Paffoni, Paola Vigano'
Summary: This article reviews the advantages and limitations of conventional IVF and discusses fundamental questions related to the technique. It provides insights into the opportunities and best practices in human c-IVF in the field of reproductive medicine.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Obstetrics & Gynecology
Jose Buratini, Mariabeatrice Dal Canto, Elena De Ponti, Fausta Brambillasca, Claudio Brigante, Silvana Gippone, Mario Mignini Renzini, Antonio La Marca
Summary: The study found that the association of basal FSH and AMH with IVF/ICSI success changes with maternal age, with basal FSH better reflecting clinical outcomes in pre-AMA patients and AMH better suiting AMA patients.
REPRODUCTIVE BIOMEDICINE ONLINE
(2021)
Article
Public, Environmental & Occupational Health
Muge Halici, Mustafa Ege Seker, Irem Yagmur Gebedek, Merve Nida Gokbak, Abdurrahman Furkan Cetisli, Ahmet Berkan Ciftci, Emine Konac, Sule Yildirim Kopuk, Bulent Tiras, Yigit Cakiroglu
Summary: This study demonstrates a correlation between TSH and AMH levels in infertile women. A TSH value of 2.88 mIU/L yields the highest AMH result. It was also found that AMH and AFC were positively correlated, while AMH and FSH were negatively correlated.
Article
Multidisciplinary Sciences
Jessica Ottolina, Michele Vignali, Enrico Papaleo, Paola Vigano, Edgardo Somigliana, Stefano Ferrari, Valeria Liprandi, Gaia Belloni, Marco Reschini, Massimo Candiani, Paolo Vercellini, Laura Benaglia
Summary: The management of endometriosis-related infertility is a challenging issue, with surgery and IVF being the two main treatment options. This study aims to compare the effectiveness and cost-effectiveness of these two approaches, and potentially influence clinical practice and resource allocation.
Article
Obstetrics & Gynecology
Hakan Cakmak
Summary: Declining oocyte quality and quantity with age are the main factors affecting female reproductive success. Factors such as the female partner's age, ovarian reserve, previous fertility treatment outcomes, and pregnancy success data are used to predict live birth rates in IVF treatment. The chance of success after the age of 45 is extremely low, making IVF cycles with autologous oocytes discouraged. The number of mature eggs retrieved and available embryos for transfer are important predictors of pregnancy and live birth. Patients aged <= 45 should consider their age and expected ovarian response when deciding to attempt IVF. Patients with a poor prognosis should be fully informed about the prognosis, risks, costs, and alternatives before starting an IVF cycle.
FERTILITY AND STERILITY
(2022)
Article
Endocrinology & Metabolism
Jie Wu, Ying-jie Zhao, Min Wang, Ming-qiang Tang, Yao-fang Liu
Summary: The analysis of data from 496 infertile patients showed no significant correlation between ovarian reserve and thyroid function in infertile women, whether grouped based on TSH levels or thyroid autoimmune antibodies.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Medicine, General & Internal
Feng Zhou, Fanxuan Zhao, Xiaoying Jin, Chao Li, Songying Zhang
Summary: This study compared ovarian reserve function and outcomes after IVF-ET for young women with pelvic endometriosis, with or without ovarian endometrioma. The study found that ovarian endometrioma significantly impairs ovarian reserve function and affects treatment efficacy. Obtaining more high-quality embryos is important for IVF-ET treatment in these patients.
Article
Obstetrics & Gynecology
N. Friis Wang, J. W. Bogstad, S. E. Pors, M. R. Petersen, A. Pinborg, C. Yding Andersen, K. Lossl
Summary: Continuous low-dose hCG administration for 8 weeks does not increase the proportion of antral follicles reaching the preovulatory state in women with low ovarian reserve.
HUMAN REPRODUCTION
(2023)
Article
Obstetrics & Gynecology
Nefise Nazli Yenigul, Runa Ozelc, Emre Baser, Serdar Dilbaz, Oya Aldemir, Berna Dilbaz, Ozlem Moraloglu Tekin
Summary: The study compared the success rates of two controlled ovarian hyperstimulation protocols in women under 35 with diminished ovarian reserve. The results showed that there were no significant differences in clinical pregnancy rate, implantation rate, miscarriage rate, and live birth rate between the two groups.
GINEKOLOGIA POLSKA
(2022)
Article
Medicine, General & Internal
Rihwa Choi, Wonseo Park, Gayoung Chun, Sang Gon Lee, Eun Hee Lee
Summary: Diminished ovarian reserve can be assessed using serum AMH and FSH tests. This study evaluated the prevalence of diminished ovarian reserve in a large population of reproductive-aged women in Korea using different cutoffs of AMH and FSH levels. The prevalence increased with age and was comparable to that in the USA. The study provides important knowledge for infertility support programs and the field of maternal aging.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Endocrinology & Metabolism
Engin Yildirim, Umit Gorkem
Summary: The circulating alarin level was significantly elevated in infertile women with poor ovarian reserve patterns. Additionally, alarin level was significantly correlated with serum LH concentration in the poor ovarian reserve pattern.
GYNECOLOGICAL ENDOCRINOLOGY
(2021)
Review
Endocrinology & Metabolism
Marcelle Cedars
Summary: This article discusses the integration of anti-Mullerian hormone (AMH) into the diagnosis and treatment of infertility. AMH can be used to estimate ovarian reserve, determine the dosage of ovarian stimulation, and predict stimulation response. However, it does not reflect oocyte health or chances for pregnancy. Low AMH levels may suggest a shortened reproductive window. AMH levels need to be interpreted in the context of the endogenous endocrine environment, and there is an inverse correlation between body mass index and AMH.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Biochemistry & Molecular Biology
Elli Anagnostou, Alexia Kafkoutsou, Despina Mavrogianni, Ekaterini Domali, Evangelia Dimitroulia, Dimitris Mathiopoulos, Peter Drakakis, Dimitris Loutradis
Summary: This study evaluated the impact of two polymorphisms in a Greek population of women undergoing IVF/ICSI program and found that the FSH 13-211 G>T polymorphism is rare in the infertile Greek population. Statistically significant differences were observed in LH levels for some polymorphisms. The study concluded that the polygenic combination of the Asn680Ser and FSH 13 subunit-211 G>T gene polymorphisms may provide additional predictive value for ovarian response to exogenous gonadotropins.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY
(2021)
Article
Chemistry, Medicinal
Yue Lin, Qianqian Chen, Jing Zhu, Yili Teng, Xuefeng Huang, Xia Chen
Summary: The present study compared the efficiency of progestin-primed ovarian stimulation (PPOS) with clomiphene citrate (CC) supplementation (PPOS+CC) and the standard PPOS protocol for women with diminished ovarian reserve (DOR) of different ages. Results showed that CC supplementation in PPOS protocols alleviated pituitary suppression and resulted in more high-quality embryos for young women with DOR. However, older women with DOR may face higher risks of premature LH surge and poor oocyte maturation rate with PPOS+CC.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2021)
Article
Medicine, General & Internal
Carlotta Scarafia, Martina Masciovecchio, Stefano Canosa, Andrea Roberto Carosso, Gianluca Gennarelli, Alberto Revelli, Chiara Benedetto
Summary: The study found that in women with ovarian endometriosis, ICSI can be performed without harming oocytes or affecting the outcome. Additionally, there is no advantage in removing endometrioma before ICSI.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Lars Berglund, Ulf Riserus, Kristina Hambraeus
UPSALA JOURNAL OF MEDICAL SCIENCES
(2019)
Article
Cardiac & Cardiovascular Systems
Tomasz Baron, Lars Berglund, Eva-Maria Hedin, Frank A. Flachskampf
CLINICAL RESEARCH IN CARDIOLOGY
(2019)
Article
Obstetrics & Gynecology
Katarina Kebbon Vaegter, Lars Berglund, Johanna Tilly, Nermin Hadziosmanovic, Thomas Brodin, Jan Holte
REPRODUCTIVE BIOMEDICINE ONLINE
(2019)
Article
Environmental Sciences
Ylva Cedervall, Anna M. Stenberg, Hanna B. Ahman, Vilmantas Giedraitis, Fredrik Tinmark, Lars Berglund, Kjartan Halvorsen, Martin Ingelsson, Erik Rosendahl, Anna Cristina Aberg
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2020)
Article
Geriatrics & Gerontology
Hanna B. Ahman, Ylva Cedervall, Lena Kilander, Vilmantas Giedraitis, Lars Berglund, Kevin J. McKee, Erik Rosendahl, Martin Ingelsson, Anna Cristina Aberg
Article
Neurosciences
Anna Cristina Aberg, Fredrik Olsson, Hanna Bozkurt Ahman, Olga Tarassova, Anton Arndt, Vilmantas Giedraitis, Lars Berglund, Kjartan Halvorsen
Summary: The new semiautomatic method aided by deep learning for estimating gait parameters from video-recorded TUG tests demonstrated good validity and reliability in the study, providing a suitable approach for quantifying gait in such assessments. The results support further exploration of cognitive-motor interference in dual-task testing.
Article
Orthopedics
Hanna B. Ahman, Lars Berglund, Ylva Cedervall, Vilmantas Giedraitis, Kevin J. McKee, Erik Rosendahl, Anna Cristina Aberg
Summary: This study aimed to establish reference values for UDDGait TUGdt test variables in cognitively healthy adults and assess their test-retest reliability. Results showed excellent reliability for time scores, fair to good reliability for number of animals and animals/10 seconds as well as months/10 seconds, and poor reliability for cost measures and number of months.
Article
Environmental Sciences
Richelle D. Bjorvang, Ida Hallberg, Anne Pikki, Lars Berglund, Matteo Pedrelli, Hannu Kiviranta, Panu Rantakokko, Paivi Ruokojarvi, Christian H. Lindh, Matts Olovsson, Sara Persson, Jan Holte, Ylva Sjunnesson, Pauliina Damdimopoulou
Summary: This study examines the impact of persistent organic pollutants (POPs) on reproductive health and finds that age plays a crucial role in the transfer of chemicals from blood to follicular fluid. Moreover, exposure to POPs is significantly associated with assisted reproductive technology (ART) outcomes.
ENVIRONMENTAL RESEARCH
(2022)
Article
Medicine, General & Internal
Azita Emami, Tores Theorell, Hyejin Kim, Lars Berglund, Helena Hallinder, Gabriella Engstrom
Summary: This study investigates the effect of music intervention on caregivers of dementia patients and finds that it can lower morning saliva cortisol concentrations for caregivers.
UPSALA JOURNAL OF MEDICAL SCIENCES
(2023)
Article
Geriatrics & Gerontology
Anna Cristina Aberg, Liss Elin Larsson, Vilmantas Giedraitis, Lars Berglund, Kjartan Halvorsen
Summary: This study investigated the effects of different TUGdt test conditions on gait among older adults. The results showed that different TUGdt conditions resulted in changes in gait parameters, with TUGdt-serial 7s causing the largest interference.
JOURNAL OF AGING AND PHYSICAL ACTIVITY
(2023)
Article
Environmental Sciences
Ida Hallberg, Richelle D. Bjoervang, Nermin Hadziosmanovic, Jacco Koekkoekk, Anne Pikki, Majorie van Duursen, Virissa Lenters, Ylva Sjunnesson, Jan Holte, Lars Berglund, Sara Persson, Matts Olovsson, Pauliina Damdimopoulou
Summary: This study identifies associations between lifestyle factors and concentrations of endocrine-disrupting chemicals (EDCs) in ovarian follicular fluid. The results suggest that multiple lifestyle variables affect chemical contamination of the follicular fluid.
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
(2023)
Article
Geriatrics & Gerontology
Anna Cristina Aberg, Johanna R. Petersson, Vilmantas Giedraitis, Kevin J. Mckee, Erik Rosendahl, Kjartan Halvorsen, Lars Berglund
Summary: This study aimed to investigate whether the results of the TUGdt test can predict the incidence of cognitive impairment in older adults. The study found that the words/time parameter of TUGdt can be used as an effective tool for predicting the incidence of cognitive impairment in older adults.
Article
Cardiac & Cardiovascular Systems
Linda Vixner, Kristina Hambraeus, Bjorn Ang, Lars Berglund
Summary: This study investigated the impact of pain after myocardial infarction (MI) on mortality. The results showed that pain 1 year after MI increases the risk of all-cause mortality, and this effect is more pronounced than smoking. Clinicians should consider patients' experienced pain when managing patients after MI.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Environmental Sciences
Hanna B. Ahman, Lars Berglund, Ylva Cedervall, Lena Kilander, Vilmantas Giedraitis, Kevin J. McKee, Martin Ingelsson, Erik Rosendahl, Anna Cristina Aberg
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2020)
Article
Cardiac & Cardiovascular Systems
Birgitta Jonelid, Bjorn Kragsterman, Lars Berglund, Bertil Andren, Nina Johnston, Bertil Lindahl, Jonas Oldgren, Christina Christersson
JRSM CARDIOVASCULAR DISEASE
(2019)