Recommendations for Analyzing and ReportingTP53Gene Variants in the High-Throughput Sequencing Era

Insights into Wild-Type and Mutant p53 Functions Provided by Genetically Engineered Mice

(2014) Lawrence A. Donehower   HUMAN MUTATION

TP53 Mutation Analysis in Clinical Practice: Lessons From Chronic Lymphocytic Leukemia

(2014) Jitka Malcikova et al.   HUMAN MUTATION

Analysis of TP53 Mutation Status in Human Cancer Cell Lines: A Reassessment

(2014) Bernard Leroy et al.   HUMAN MUTATION

GermlineTP53Mutations and the Changing Landscape of Li-Fraumeni Syndrome

(2014) Junne Kamihara et al.   HUMAN MUTATION

TP53 Mutations in Human Cancer: Database Reassessment and Prospects for the Next Decade

(2014) Bernard Leroy et al.   HUMAN MUTATION

Discovery and saturation analysis of cancer genes across 21 tumour types

(2014) Michael S. Lawrence et al.   NATURE

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

(2014) C. Bettegowda et al.   Science Translational Medicine

Single nucleotide variation in the TP53 3' untranslated region in diffuse large B-cell lymphoma treated with rituximab-CHOP: a report from the International DLBCL Rituximab-CHOP Consortium Program

(2013) Y. Li et al.   BLOOD

Mapping the p53 transcriptome universe using p53 natural polymorphs

(2013) B Wang et al.   CELL DEATH AND DIFFERENTIATION

Association betweenTP53R249S mutation and polymorphisms inTP53intron 1 in hepatocellular carcinoma

(2013) Sandra Ortiz-Cuaran et al.   GENES CHROMOSOMES & CANCER

Impact of Neonatal Screening and Surveillance for the TP53 R337H Mutation on Early Detection of Childhood Adrenocortical Tumors

(2013) Gislaine Custódio et al.   JOURNAL OF CLINICAL ONCOLOGY

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA

(2013) Muhammed Murtaza et al.   NATURE

Locus Reference Genomic: reference sequences for the reporting of clinically relevant sequence variants

(2013) Jacqueline A. L. MacArthur et al.   NUCLEIC ACIDS RESEARCH

The mutant p53 mouse as a pre-clinical model

(2013) J G Jackson et al.   ONCOGENE

Functional DNA quantification guides accurate next-generation sequencing mutation detection in formalin-fixed, paraffin-embedded tumor biopsies

(2013) Sachin Sah et al.   Genome Medicine

ERIC recommendations on TP53 mutation analysis in chronic lymphocytic leukemia

(2012) S Pospisilova et al.   LEUKEMIA

Architecture of the human regulatory network derived from ENCODE data

(2012) Mark B. Gerstein et al.   NATURE

The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis

(2012) Bernard Leroy et al.   NUCLEIC ACIDS RESEARCH

Data-driven unbiased curation of the TP53 tumor suppressor gene mutation database and validation by ultradeep sequencing of human tumors

(2012) K. Edlund et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aurora B kinase phosphorylates and instigates degradation of p53

(2012) C. P. Gully et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TP53 genomics predict higher clinical and pathologic tumor response in operable early-stage breast cancer treated with docetaxel-capecitabine ± trastuzumab

(2011) Stefan Glück et al.   BREAST CANCER RESEARCH AND TREATMENT

A germline variant in the TP53 polyadenylation signal confers cancer susceptibility

(2011) Simon N Stacey et al.   NATURE GENETICS

Understanding the contribution of synonymous mutations to human disease

(2011) Zuben E. Sauna et al.   NATURE REVIEWS GENETICS

The p53 family: guardians of maternal reproduction

(2011) Arnold J. Levine et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Characterization of Novel and Uncharacterized p53 SNPs in the Chinese Population – Intron 2 SNP Co-Segregates with the Common Codon 72 Polymorphism

(2011) Beng Hooi Phang et al.   PLoS One

In vivo analysis of p53 tumor suppressor function using genetically engineered mouse models

(2010) D. K. Broz et al.   CARCINOGENESIS

p53 directly transactivates Δ133p53α, regulating cell fate outcome in response to DNA damage

(2010) M Aoubala et al.   CELL DEATH AND DIFFERENTIATION

Somatic mutations in cancer prognosis and prediction: lessons from TP53 and EGFR genes

(2010) Magali Olivier et al.   CURRENT OPINION IN ONCOLOGY

Genome remodelling in a basal-like breast cancer metastasis and xenograft

(2010) Li Ding et al.   NATURE

Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy

(2010) Jordi Barretina et al.   NATURE GENETICS

Locus Reference Genomic sequences: an improved basis for describing human DNA variants

(2010) Raymond Dalgleish et al.   Genome Medicine

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Wrap53, a Natural p53 Antisense Transcript Required for p53 Induction upon DNA Damage

(2009) Salah Mahmoudi et al.   MOLECULAR CELL

A comparison between p53 accumulation determined by immunohistochemistry andTP53mutations as prognostic variables in tumours from breast cancer patients

(2008) Jan Alsner et al.   ACTA ONCOLOGICA

Sequence variant classification and reporting: recommendations for improving the interpretation of cancer susceptibility genetic test results

(2008) Sharon E. Plon et al.   HUMAN MUTATION

GENETICS: The Human Variome Project

(2008) R. G. H. Cotton et al.   SCIENCE