Differential effects of AKT1(p.E17K) expression on human mammary luminal epithelial and myoepithelial cells

AKT1 (E17K) Mutation in Pancreatic Cancer

(2014) Azim Mohamedali et al.   TECHNOLOGY IN CANCER RESEARCH & TREATMENT

The GRP1 PH Domain, Like the AKT1 PH Domain, Possesses a Sentry Glutamate Residue Essential for Specific Targeting to Plasma Membrane PI(3,4,5)P3

(2011) Carissa Pilling et al.   BIOCHEMISTRY

A Mosaic Activating Mutation inAKT1Associated with the Proteus Syndrome

(2011) Marjorie J. Lindhurst et al.   NEW ENGLAND JOURNAL OF MEDICINE

Deactivation of Akt by a small molecule inhibitor targeting pleckstrin homology domain and facilitating Akt ubiquitination

(2011) H. Jo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activating E17K mutation in the gene encoding the protein kinase AKT in a subset of squamous cell carcinoma of the lung

(2010) Donatella Malanga et al.   CELL CYCLE

The Akt activation inhibitor TCN-P inhibits Akt phosphorylation by binding to the PH domain of Akt and blocking its recruitment to the plasma membrane

(2010) N Berndt et al.   CELL DEATH AND DIFFERENTIATION

A Small Molecule Inhibits Akt through Direct Binding to Akt and Preventing Akt Membrane Translocation

(2010) Donghwa Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global Phosphoproteomics Identifies a Major Role for AKT and 14-3-3 in Regulating EDC3

(2010) Mark Larance et al.   MOLECULAR & CELLULAR PROTEOMICS

Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations

(2010) J Lauring et al.   ONCOGENE

Phosphatidylinositol-3-kinase and AKT1 mutations occur early in breast carcinoma

(2009) Jennifer Dunlap et al.   BREAST CANCER RESEARCH AND TREATMENT

High prevalence of PIK3CA/AKT pathway mutations in papillary neoplasms of the breast

(2009) Megan L Troxell et al.   MODERN PATHOLOGY

Absence of AKT1 Mutations in Glioblastoma

(2009) Fonnet E. Bleeker et al.   PLoS One

The Guanine Nucleotide Exchange Factors Trio, Ect2, and Vav3 Mediate the Invasive Behavior of Glioblastoma

(2008) Bodour Salhia et al.   AMERICAN JOURNAL OF PATHOLOGY

Absence of E17K mutation in the pleckstrin homology domain ofAKT1in gastrointestinal and liver cancers in the Korean population

(2008) Zhang Cao et al.   APMIS

Molecular Mechanism of an Oncogenic Mutation That Alters Membrane Targeting: Glu17Lys Modifies the PIP Lipid Specificity of the AKT1 PH Domain†

(2008) Kyle E. Landgraf et al.   BIOCHEMISTRY

DAnTE: a statistical tool for quantitative analysis of -omics data

(2008) A. D. Polpitiya et al.   BIOINFORMATICS

The transforming mutation E17K/AKT1 is not a major event in B-cell-derived lymphoid leukaemias

(2008) I S Mahmoud et al.   BRITISH JOURNAL OF CANCER

Mutational analysis of oncogenic AKT E17K mutation in common solid cancers and acute leukaemias

(2008) M S Kim et al.   BRITISH JOURNAL OF CANCER

Chronic lymphocytic leukaemia and acute myeloid leukaemia are not associated with AKT1 pleckstrin homology domain (E17K) mutations

(2008) T. Zenz et al.   BRITISH JOURNAL OF HAEMATOLOGY

An Integrative Genomic and Proteomic Analysis of PIK3CA, PTEN, and AKT Mutations in Breast Cancer

(2008) K. Stemke-Hale et al.   CANCER RESEARCH

Akt1 inhibition by RNA interference sensitizes human non-small cell lung cancer cells to cisplatin

(2008) Myoung Woo Lee et al.   INTERNATIONAL JOURNAL OF CANCER

c-Jun Supports Ribosomal RNA Processing and Nucleolar Localization of RNA Helicase DDX21

(2008) Tim H. Holmström et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AKT1 E17K in human solid tumours

(2008) F E Bleeker et al.   ONCOGENE