Genome-wide analysis of familial dysautonomia and kinetin target genes with patient olfactory ecto-mesenchymal stem cells

SHH propagates distal limb bud development by enhancing CYP26B1-mediated retinoic acid clearance via AER-FGF signalling

(2011) S. Probst et al.   DEVELOPMENT

Specific correction of a splice defect in brain by nutritional supplementation

(2011) R. S. Shetty et al.   HUMAN MOLECULAR GENETICS

IKAP/Elp1 involvement in cytoskeleton regulation and implication for familial dysautonomia

(2011) D. Cheishvili et al.   HUMAN MOLECULAR GENETICS

Engraftment of human nasal olfactory stem cells restores neuroplasticity in mice with hippocampal lesions

(2011) Emmanuel Nivet et al.   JOURNAL OF CLINICAL INVESTIGATION

Lyn Kinase Regulates Mesolimbic Dopamine Release: Implication for Alcohol Reward

(2011) S. L. Gibb et al.   JOURNAL OF NEUROSCIENCE

Cxcr7 Controls Neuronal Migration by Regulating Chemokine Responsiveness

(2011) Juan Antonio Sánchez-Alcañiz et al.   NEURON

Kinetin Improves IKBKAP mRNA Splicing in Patients With Familial Dysautonomia

(2011) Felicia B Axelrod et al.   PEDIATRIC RESEARCH

Effects of IKAP/hELP1 Deficiency on Gene Expression in Differentiating Neuroblastoma Cells: Implications for Familial Dysautonomia

(2011) Rachel Cohen-Kupiec et al.   PLoS One

NRF2 Activation Restores Disease Related Metabolic Deficiencies in Olfactory Neurosphere-Derived Cells from Patients with Sporadic Parkinson's Disease

(2011) Anthony L. Cook et al.   PLoS One

Functions of Fasciculation and Elongation Protein Zeta-1 (FEZ1) in the Brain

(2011) Andrés D. Maturana et al.   TheScientificWorldJOURNAL

Slug (SNAI2) expression in oral SCC cells results in altered cell-cell adhesion and increased motility

(2011) Dawn Katafiasz et al.   Cell Adhesion & Migration

Disease-specific, neurosphere-derived cells as models for brain disorders

(2010) N. Matigian et al.   Disease Models & Mechanisms

Regulation of peripheral myelination by Src-like kinases

(2010) Shireen Hossain et al.   EXPERIMENTAL NEUROLOGY

Experience with carrier screening and prenatal diagnosis for 16 Ashkenazi Jewish genetic diseases

(2010) Stuart A. Scott et al.   HUMAN MUTATION

A role for the elongator complex in zygotic paternal genome demethylation

(2010) Yuki Okada et al.   NATURE

Cholinergic regulation of striatal Nova mRNAs

(2010) N. Jelen et al.   NEUROSCIENCE

Phosphatidylserine Increases IKBKAP Levels in Familial Dysautonomia Cells

(2010) Hadas Keren et al.   PLoS One

Olfactory Stem Cells, a New Cellular Model for Studying Molecular Mechanisms Underlying Familial Dysautonomia

(2010) Nathalie Boone et al.   PLoS One

 -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro

(2010) J. Burre et al.   SCIENCE

Nrg1/ErbB signaling networks in Schwann cell development and myelination

(2010) Jason Newbern et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Role for Reelin in stabilizing cortical architecture

(2010) Michael Frotscher   TRENDS IN NEUROSCIENCES

Loss-of-function of IKAP/ELP1

(2010) Tiina Naumanen et al.   Cell Adhesion & Migration

The Caenorhabditis elegans Elongator Complex Regulates Neuronal α-tubulin Acetylation

(2010) Jachen A. Solinger et al.   PLoS Genetics

Elongator Controls the Migration and Differentiation of Cortical Neurons through Acetylation of α-Tubulin

(2009) Catherine Creppe et al.   CELL

ALCAM Regulates Mediolateral Retinotopic Mapping in the Superior Colliculus

(2009) M. Buhusi et al.   JOURNAL OF NEUROSCIENCE

Semaphorin 5A promotes angiogenesis by increasing endothelial cell proliferation, migration, and decreasing apoptosis

(2009) Anguraj Sadanandam et al.   MICROVASCULAR RESEARCH

Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs

(2009) Gabsang Lee et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Rescuing Z+ agrin splicing in Nova null mice restores synapse formation and unmasks a physiologic defect in motor neuron firing

(2009) M. Ruggiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Human Nose Harbors a Niche of Olfactory Ectomesenchymal Stem Cells Displaying Neurogenic and Osteogenic Properties

(2009) Bruno Delorme et al.   STEM CELLS AND DEVELOPMENT

Defects in tRNA Modification Associated with Neurological and Developmental Dysfunctions in Caenorhabditis elegans Elongator Mutants

(2009) Changchun Chen et al.   PLoS Genetics

The Elongator Complex Interacts with PCNA and Modulates Transcriptional Silencing and Sensitivity to DNA Damage Agents

(2009) Qing Li et al.   PLoS Genetics

Semaphorin 5A is a bifunctional axon guidance cue for axial motoneurons in vivo

(2008) Jona D. Hilario et al.   DEVELOPMENTAL BIOLOGY

IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration

(2008) L. D. Johansen et al.   JOURNAL OF CELL SCIENCE

Loss of Mouse Ikbkap, a Subunit of Elongator, Leads to Transcriptional Deficits and Embryonic Lethality That Can Be Rescued by Human IKBKAP

(2008) Y.-T. Chen et al.   MOLECULAR AND CELLULAR BIOLOGY