A review of a multifactorial probability-based model for classification of BRCA1 and BRCA2 variants of uncertain significance (VUS)
Published 2011 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A review of a multifactorial probability-based model for classification of BRCA1 and BRCA2 variants of uncertain significance (VUS)
Authors
Keywords
-
Journal
HUMAN MUTATION
Volume 33, Issue 1, Pages 8-21
Publisher
Wiley
Online
2011-10-12
DOI
10.1002/humu.21627
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A Computational Method to Classify Variants of Uncertain Significance Using Functional Assay Data with Application to BRCA1
- (2011) E. S. Iversen et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Splicing and multifactorial analysis of intronic BRCA1 and BRCA2 sequence variants identifies clinically significant splicing aberrations up to 12 nucleotides from the intron/exon boundary
- (2011) Phillip J. Whiley et al. HUMAN MUTATION
- Comprehensive Analysis of Missense Variations in the BRCT Domain of BRCA1 by Structural and Functional Assays
- (2010) Megan S. Lee et al. CANCER RESEARCH
- LOH analysis should not be used as a tool to assess whether UVs of BRCA1/2 are pathogenic or not
- (2010) E. Beristain et al. Familial Cancer
- A simple method for co-segregation analysis to evaluate the pathogenicity of unclassified variants; BRCA1 and BRCA2 as an example
- (2009) Leila Mohammadi et al. BMC CANCER
- Characterization of BRCA1 ring finger variants of uncertain significance
- (2009) Kevin Sweet et al. BREAST CANCER RESEARCH AND TREATMENT
- Expression of human BRCA1 variants in mouse ES cells allows functional analysis of BRCA1 mutations
- (2009) Suhwan Chang et al. JOURNAL OF CLINICAL INVESTIGATION
- Expression profiling of familial breast cancers demonstrates higher expression of FGFR2 in BRCA2-associated tumors
- (2008) Anita L. Bane et al. BREAST CANCER RESEARCH AND TREATMENT
- The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions
- (2008) A C Antoniou et al. BRITISH JOURNAL OF CANCER
- Functional Assays for Classification of BRCA2 Variants of Uncertain Significance
- (2008) D. J. Farrugia et al. CANCER RESEARCH
- Classification of rare missense substitutions, using risk surfaces, with genetic- and molecular-epidemiology applications
- (2008) Sean V. Tavtigian et al. HUMAN MUTATION
- Genetic evidence and integration of various data sources for classifying uncertain variants into a single model
- (2008) David E. Goldgar et al. HUMAN MUTATION
- Tumor characteristics as an analytic tool for classifying genetic variants of uncertain clinical significance
- (2008) Robert M.W. Hofstra et al. HUMAN MUTATION
- Sequence variant classification and reporting: recommendations for improving the interpretation of cancer susceptibility genetic test results
- (2008) Sharon E. Plon et al. HUMAN MUTATION
- Clinically Applicable Models to CharacterizeBRCA1andBRCA2Variants of Uncertain Significance
- (2008) Andrew D. Spearman et al. JOURNAL OF CLINICAL ONCOLOGY
- Clinical Classification ofBRCA1andBRCA2DNA Sequence Variants: The Value of Cytokeratin Profiles and Evolutionary Analysis—A Report From the kConFab Investigators
- (2008) Amanda B. Spurdle et al. JOURNAL OF CLINICAL ONCOLOGY
- Mouse embryonic stem cell–based functional assay to evaluate mutations in BRCA2
- (2008) Sergey G Kuznetsov et al. NATURE MEDICINE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now